Localised airway reactivity as a determinant of asthma control and AHR

局部气道反应性是哮喘控制和 AHR 的决定因素

• 批准号: nhmrc : 1031701
• 负责人: Dr Cheryl Salome
• 金额: $ 20.44万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/localised-airway-reactivity-control-ahr/110819
• 关键词: Localised; airway; reactivity; determinant; asthma

Asthma morbidity and mortality remain high, with drug cost, days lost from school and work. This may be due to severe asthma in which control cannot be attained. This may be due to localised regions of lung that remain persistently responsive to inhaled irritants. We will examine the location and size of these regions using 3-dimensional ventilation scanning. The potential importance of our findings is in providing a basis for improving treatment in resistant, severe asthma.

哮喘的发病率和死亡率仍然很高，药物费用高，上学和工作的天数少。这可能是由于无法控制的严重哮喘所致。这可能是由于肺的局部区域持续对吸入刺激物有反应。我们将使用三维通风扫描检查这些区域的位置和大小。我们的发现的潜在重要性在于为改善治疗难治性严重哮喘提供了基础。