University of Wisconsin Transplant Reseach Training Program

项目总结 威斯康星州大学移植研究培训计划代表着一种基本的资助机制，用于 我们所在机构和全国范围内的博士生和住院医生。“UW移植”的总体目标 研究培训计划“是为有强烈职业抱负的博士后实习生提供 与移植相关的研究，具有两年的、全面的、基于假设的研究经验。实习生 将接受包括临床试验原理、研究设计、管理、伦理学和 数据分析。培训计划将促进知识、技能、职业态度和 成功的学术生涯所需的经验。该计划每年保留两名实习生，为期一年 两年培训经验(每年接受两名新学员)。我们的教练员池共有12名 教职员工，代表六个系，包括细胞和再生医学，医学微生物学和 免疫学、医学、病理学和检验医学、儿科学和外科。教练员们已经 选择依据是校外研究支持、先前的指导经验、研究目标与 培训计划，以及在从事翻译研究方面已经存在的合作。总体而言，他们 在过去的10年里，我指导了超过115名博士后实习生，包括医学博士和博士。 这一方案的具体目标是：(A)提供进行基本的、翻译的 临床移植研究的重点是通过参与个人和 量身定制的教学和指导计划，以及(B)将医学博士和博士后实习生培养为有技能的 以团队为导向的科学家，强调移植研究。选择的三个重点领域 该计划涵盖了威斯康星大学在移植研究方面的主要研究举措：i) 免疫生物学/免疫调节，ii)细胞疗法/再生医学，以及iii)翻译 通过大型动物模型进行研究。该计划的优势包括资助研究的广度 涵盖基础细胞体外项目、小鼠模型、灵长类动物和人类研究；经验丰富的训练师 与威斯康星大学临床和翻译研究所(卢旺达问题国际法庭)合作，由CTSA资助；以及 鼓励临床医生和科学家之间的互动和交叉培训的培训模式。另外 该计划拥有个性化的培训计划，广泛的机构资源来加强培训，以及 有经验的行政基础设施，协助管理方案，促进计划 通过招聘和留住妇女和少数群体实现多样性，并制定一项全面的培训计划 负责任的研究行为。行政结构包括一个执行委员会、一个外部机构 咨询委员会、多样性咨询委员会以及方案支助和协调，利用 外科部门现有的培训补助计划管理员。

PROJECT SUMMARY The UW Transplant Research Training Program represents an essential funding mechanism for post- doctoral trainees and residents at our own institution and nationwide. The overall goal of the “UW Transplant Research Training Program” is to provide postdoctoral trainees who are strongly motivated toward a career in transplant related research, with a two-year, comprehensive, hypothesis-based research experience. Trainees will be exposed to a curriculum including principles of clinical trials, research design, management, ethics and data analysis. The training program will foster the development of knowledge, skills, professional attitudes, and experience required for successful academic careers. The program will maintain two trainees per year for a two-year training experience (accepting two new trainees each year). Our trainer pool includes a total of 12 faculty, representing six departments, including Cell and Regenerative Medicine, Medical Microbiology and Immunology, Medicine, Pathology and Laboratory Medicine, Pediatrics, and Surgery. Trainers have been selected based on extramural research support, prior mentoring experience, relevance of research goals to the training program, and already existing collaborations in the pursuit of translational research. Collectively, they have mentored over 115 post-doctoral trainees over the past 10 years including both MDs and PhDs. The specific objectives of this program are: (A) to provide training in the conduct of basic, translational and clinical transplant research focused on improving human health through participation in an individual and tailored didactic and mentoring program, and (B) to develop MD and PhD post-doctoral trainees as skilled team-oriented scientists with an emphasis on transplant research. The three areas of focus chosen for the program encompass the major research initiatives in transplant research at University of Wisconsin: i.) Immunobiology/ Immune Regulation, ii) Cellular Therapies/Regenerative Medicine, and iii) Translational research via large animal models. The strengths of the program include the breadth of funded research covering basic cellular in vitro projects, murine models, primates and human studies; an experienced trainer pool; collaboration with the UW Institute for Clinical and Translational Research (ICTR) funded by a CTSA; and a training model that encourages interactions and cross-training between clinicians and scientists. Additionally this program boasts individualized training plans, extensive institutional resources to enhance training, an experienced administrative infrastructure to assist with management of the program, a plan to promote diversity by recruiting and retaining both women and minorities, and a comprehensive plan for training in the responsible conduct of research. The administrative structure includes an Executive Committee, an External Advisory Board, a Diversity Advisory Committee, as well as program support and coordination utilizing an existing training grant program administrator within the Department of Surgery.