ZeroG TRIP: Training Responses in Postural Rehabilitation

ZeroG TRIP：姿势康复训练反应

• 批准号: 9345110
• 负责人: Joseph M. Hidler
• 金额: $ 22.47万
• 依托单位: ARETECH, LLC
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-15 至 2019-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9345110
• 关键词: Adverse event; Age; Aging; Algorithms; Balance training; Body Weight; Characteristics; Clinical; Computers; Development; Devices; Elderly; Equilibrium; Feedback; Gait; Gait abnormality; Gait speed; Goals; Impairment; Individual; Injury; Intuition; Laboratories; Laboratory Study; Manuals; Movement; Neurologic; Parkinson Disease; Patients; Phase; Posture; Quality of life; Questionnaires; Recruitment Activity; Rehabilitation therapy; Research Personnel; Robotics; Safety; Small Business Innovation Research Grant; System; Tablets; Technology; Testing; Training; Translating; Virginia; Walking; Wireless Technology; Work; base; clinical practice; disability; equilibration disorder; experience; fall risk; falls; flexibility; gait rehabilitation; high risk; improved; innovation; instrumentation; nervous system disorder; physical therapist; prevent; prototype; rehabilitation technology; research clinical testing; response; safety practice; sensor; touchscreen; usability

Project Summary The goal of this project is to significantly enhance our understanding and treatment of inadequate balance responses in the elderly and in patients with neurological impairments following external perturbations such as a slip or trip. Our laboratory studies have shown that balance responses can be improved with practice in the elderly and in patients with Parkinson's disease (PD). However, these laboratory studies have not been translated into clinical practice because there is currently no safe and reliable technology for training and quantifying balance responses, particularly during overground walking. The ZeroG gait and balance training system developed and now commercialized by Aretech, LLC (Ashburn, VA) allows individuals with gait and balance disorders to safety practice walking overground with concurrent body-weight support and fall protection. The current system does not allow patients to practice recovering from unexpected external perturbation for balance training nor does the system contain the necessary instrumentation for quantifying balance responses. In this Phase I SBIR, we will significantly enhance the capabilities of the ZeroG system by developing controlled balance perturbations of adjustable magnitude and direction that can be delivered during standing and overground walking. The framework for the ZeroG balance perturbation sequences, called TRIP (Train Responses in Postural Rehabilitation), will be based upon the scientific findings of our laboratory over the last decade. We will develop the specific perturbation characteristics needed to train postural stepping responses in people with balance deficits due to PD and work closely with physical therapists on usability and safety. Finally, we will determine the feasibility and clinical usability of the ZeroG TRIP system through questionnaire feedback from patients and therapists. Phase II of this SBIR will focus on additional technical development of the ZeroG TRIP system and subsequent clinical testing of the device. Specifically, we plan to develop and test innovative metrics of postural stepping responses for ZeroG TRIP using the body-worn sensors with the partnership between Aretech, LLC and APDM, Inc. We will also utilize the APDM sensors to track the patient's movements throughout the gait cycle so that we can automatically trigger the TRIP perturbation rather than having to manually trigger the perturbation. Finally, we will refine the user interfaces on both the touch screen computer and wireless tablet, making the controls intuitive for the user yet providing sufficient flexibility to control the perturbation sequences. The clinical testing during Phase II will focus on comparing improvements in balance responses and balance confidence after training with TRIP compared to ZeroG body-weight support walking in people with PD. The ZeroG TRIP system will enable physical therapists to safely and systematically assess and treat inadequate balance responses, which are a major contributor to falls, disability, and declining quality of life.

项目摘要 这个项目的目标是显著提高我们对不充分平衡的理解和治疗 老年人和神经损伤患者在外部扰动后的反应， 滑倒或绊倒我们的实验室研究表明，平衡反应可以改善与实践中， 老年人和帕金森病（PD）患者。然而，这些实验室研究并没有被 转化为临床实践，因为目前没有安全可靠的技术进行培训， 量化平衡反应，特别是在地上行走期间。ZeroG步态和平衡训练 由Aretech，LLC（Ashburn，VA）开发并现已商业化的系统允许具有步态和 平衡障碍，安全练习地上行走，同时伴有体重支撑和跌倒 保护目前的系统不允许患者练习从意外的外部 该系统也不包含用于量化的必要仪器 平衡反应。 在第一阶段SBIR中，我们将通过开发 可在站立期间提供可调节幅度和方向的受控平衡扰动 和地上行走。ZeroG平衡扰动序列的框架，称为TRIP（Train 在姿势康复的反应），将基于我们的实验室在过去的科学发现 十年我们将开发训练姿势步进反应所需的特定扰动特性 在PD导致平衡缺陷的人群中，与物理治疗师密切合作，提高可用性和安全性。 最后，我们将通过问卷调查确定ZeroG TRIP系统的可行性和临床可用性 来自患者和治疗师的反馈。 该SBIR的第二阶段将侧重于零重力TRIP系统的额外技术开发， 器械的临床试验。具体来说，我们计划开发和测试创新的姿势步进指标 响应零TRIP使用身体佩戴传感器与合作伙伴之间的Aretech，LLC和 APDM公司我们还将利用APDM传感器来跟踪患者在整个步态周期中的运动 这样我们就可以自动触发TRIP扰动，而不必手动触发 扰动最后，我们将完善触摸屏电脑和无线平板电脑的用户界面， 使得控制对于用户来说是直观的，还提供足够的灵活性来控制扰动序列。 第二阶段的临床测试将集中在比较平衡反应和平衡的改善。 PD患者TRIP训练后的信心与ZeroG体重支持步行相比。 ZeroG TRIP系统将使物理治疗师能够安全和系统地评估和治疗 平衡反应不足，这是导致福尔斯、残疾和生活质量下降的主要因素。