Mouthpiece for mTBI Detection during Adolescent Contact and Collision Sports

用于青少年接触和碰撞运动期间 mTBI 检测的喉舌

• 批准号: 9407260
• 负责人: DANIEL S HEDIN
• 金额: $ 75.65万
• 依托单位: ADVANCED MEDICAL ELECTRONICS CORPORATION
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-05 至 2019-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9407260
• 关键词: Acceleration; Adolescent; Advisory Committees; Affect; Algorithms; Athletic; Awareness; Behavior Therapy; Behavioral; Biological Models; Biomechanics; Biometry; Brain; Brain Concussion; Brain Injuries; Cellular Phone; Centers for Disease Control and Prevention (U.S.); Cessation of life; Chairperson; Charge; Child; Clinic; Clinical; Cloud Service; Computer software; Consult; Custom; Data; Detection; Doctor of Philosophy; Dose; Education; Electrical Engineering; Emotional; Engineering; Event; Exercise; Feedback; Field Hockey; Goals; Grant; Guidelines; Health; Helmet; Home environment; Individual; Industry; Injury; Laws; Lead; Learning Disabilities; Link; Long-Term Effects; Manufactured basketball; Manufactured football; Manufacturer Name; Measurement; Measures; Medical Device; Memory; Monitor; Neurocognitive Deficit; Neurologic; Neurological outcome; Oral cavity; Outcome; Phase; Physician Executives; Play; Positioning Attribute; Post-Concussion Syndrome; Principal Investigator; Process; Production; Public Health; Quality of life; Rehabilitation therapy; Reporting; Research; Research Personnel; Resources; Rest; Risk; Risk Management; Rotation; Safety; Sales; Secure; Sensitivity and Specificity; Severities; Signs and Symptoms; Soccer; Sports; Symptoms; Syndrome; System; Technology; Teenagers; Testing; Time; Traumatic Brain Injury; Uncertainty; Unconscious State; United States National Institutes of Health; Wireless Technology; Work; Youth; adverse outcome; aged; base; boys; career; college; commercialization; concussive symptom; cost; data exchange; design; dosimetry; experience; girls; head impact; healing; high risk; improved; in vivo; member; mild traumatic brain injury; neurosurgery; new technology; prevent; programs; prototype; research and development; research clinical testing; safety testing; sensor; skills; tool; web interface

Project Summary/Abstract There is a need for new inexpensive tools to discover potential concussive events or mild traumatic brain injuries (mTBIs) on the playing field. As we discover more about the long term effects of concussions, sub- concussive blows, and the importance of rest following a concussive event, the need for tools to identify concussions is becoming an increasing public concern. Many of these nominally “mild” injuries lead to poor neurological outcomes that adversely affect an individual's quality of life – i.e. second impact syndrome, post concussion syndrome, and long lasting neurocognitive deficits such as learning disabilities, memory problems, and emotional or behavioral changes. Despite increasing public awareness of this issue, TBIs are difficult to identify as athletes commonly hide the signs and symptoms, only 10% of cases result in loss of consciousness, and other mTBI signs and symptoms may only last for fifteen minutes or fewer. Recognition of TBI's during sports activities is very important because individuals with TBI's are much more vulnerable, given further impacts, to more severe brain injury until they are healed. Additionally, while recent research indicates that younger athletes are more likely to sustain an mTBI and are more vulnerable to long term effects, there is little actual data linking clinical outcomes with biomechanical assessment for pre-teens and adolescents. Since there is currently no helmet or safety gear that is protective against concussion during athletics, many resources are being put into concussion education and risk management. Risk management is currently centered on the macro scale with strict return to play guidelines and league rules or state laws that prohibit full contact practices more than three times a week for example. The proposed solution uses a unique design to provide a mouthpiece with better accuracy and/or lower cost than currently available commercial products that can be used in all sports. The solution will provide a sideline alert of a potential concussion for further clinical evaluation and head impact dosimetry. The research team assembled for this project includes a commercialization partner with current custom mouthpiece products and deep industry ties, a successful engineering team, and a research group that has performed previous mouthpiece impact sensor studies.

项目概要/摘要 需要新的廉价工具来发现潜在的脑震荡事件或轻度脑外伤 运动场上的伤害（mTBIs）。随着我们更多地了解脑震荡的长期影响， 震荡打击，以及震荡事件后休息的重要性，需要工具来识别 脑震荡正成为公众日益关注的问题。许多名义上的“轻微”伤害会导致身体状况不佳 对个人生活质量产生不利影响的神经系统结果 - 即第二次影响综合症，后 脑震荡综合症和长期持续的神经认知缺陷，例如学习障碍、记忆问题、 以及情绪或行为的变化。尽管公众对这一问题的认识不断提高，但 TBI 仍难以解决 由于运动员通常会隐藏体征和症状，只有 10% 的病例会导致意识丧失， 其他 mTBI 体征和症状可能仅持续十五分钟或更短时间。 TBI 期间的识别 体育活动非常重要，因为患有 TBI 的人更容易受到伤害，进一步考虑 影响，导致更严重的脑损伤，直到痊愈。此外，虽然最近的研究表明 年轻运动员更有可能遭受 mTBI，并且更容易受到长期影响，但几乎没有 将临床结果与青春期前和青少年的生物力学评估联系起来的实际数据。自从 目前还没有头盔或安全装备可以在运动过程中防止脑震荡，许多 资源正在投入脑震荡教育和风险管理。目前风险管理 以宏观尺度为中心，有严格的重返比赛指导方针和联盟规则或禁止全面禁止的州法律 例如，每周接触练习超过三次。所提出的解决方案采用独特的设计 提供比目前可用的商业产品具有更好的准确性和/或更低的成本的吹嘴 可用于所有运动。该解决方案将为进一步的临床提供潜在脑震荡的边线警报 评估和头部撞击剂量测定。为本项目组建的研究团队包括 与当前定制烟嘴产品和深厚的行业联系的商业化合作伙伴，成功 工程团队和一个之前进行过咬嘴冲击传感器研究的研究小组。