Portable EEG Recorder for Household Surveys

用于家庭调查的便携式脑电图记录仪

• 批准号: 7172053
• 负责人: DANIEL S HEDIN
• 金额: $ 10万
• 依托单位: ADVANCED MEDICAL ELECTRONICS CORPORATION
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7172053
• 关键词: Age; Aging; Alzheimer' s Disease; Amplifiers; Anatomy; Apple; Brain; Brain Diseases; Businesses; Characteristics; Clinical; Computer Simulation; Computer software; Computers; Country; Daily; Data; Data Quality; Dementia; Deterioration; Development Plans; Devices; Diagnostic; Elderly; Electrodes; Electroencephalogram; Electronics; Ensure; Epilepsy; Equipment; Explosion; Future; Goals; Grant; Home environment; Hour; Household; Left; Letters; Literature; Lithium; Longitudinal Studies; Longitudinal Surveys; Magnetic Resonance Imaging; Manufacturer Name; Marketing; Mechanics; Medical; Medical Electronics; Memory; Modeling; Monitor; Music; Patients; Persons; Phase; Poaceae; Positron-Emission Tomography; Postage Stamps; Price; Principal Investigator; Production; Provider; Reporting; Research; Research Personnel; Resources; Rhode Island; Sales; Scalp structure; Scheme; Small Business Funding Mechanisms; Small Business Innovation Research Grant; Surveys; Symptoms; System; Technology; Testing; Time; Training; Twin Multiple Birth; United States Food and Drug Administration; United States National Institutes of Health; Weight; Work; age related; base; commercial application; commercialization; cost; density; design; digital; experience; innovation; instrument; interest; patient monitoring device; programs; prototype; size; tool

DESCRIPTION (provided by applicant): Advanced Medical Electronics Corporation (AME) proposes to develop a miniature portable electroencephalograph (EEG) recorder that can be easily used in the home to collect data for longitudinal surveys of the elderly. The device will be capable of using new dry electrode technology that promises to greatly simplify the attachment of EEG scalp electrodes. Dry electrode technology will allow a minimally trained person to make the attachment to a patient and collect a 30 minute segment of data. In phase I, AME will identify the most promising dry electrode technology to integrate with the recorder in phase II. The proposed pocket size EEG recorder will be small enough to be worn relatively unobtrusive during daily activities. This will allow the device to be used in ambulatory epilepsy monitoring applications and will create a larger market for the portable EEG recorder. Researchers conducting longitudinal EEG surveys will benefit by sharing a market with ambulatory epilepsy monitoring because of reduced production costs. Alzheimer's disease (AD) is an age-related and irreversible brain disorder that develops over a period of years. AD symptoms typically first appear after age 65 and are the subject of longitudinal studies. There has been recent interest in the use of the electroencephalogram (EEG) to screen patients and identify the first signs of AD. There is extensive literature that reports changes in quantitative electroencephalogram (QEEG) with aging and a relationship between magnitude of changes and degree of clinical deterioration in progressive dementia. The use of EEG provides a low cost alternative to more sophisticated tools like MRI and PET to distinguish characteristics of brain function and anatomy that indicate future problems. The proposed miniature portable EEG recorder with easily applied dry electrode technology can be applied in the home to collect data for longitudinal surveys of the elderly.

描述（由申请人提供）：Advanced Medical Electronics Corporation（AME）拟开发一种微型便携式脑电图（EEG）记录仪，可在家中轻松使用，以收集老年人纵向调查的数据。该设备将能够使用新的干电极技术，有望大大简化EEG头皮电极的连接。干电极技术将允许经过最低限度培训的人员与患者连接并收集30分钟的数据。在第一阶段，AME将确定最有前途的干电极技术，以便在第二阶段与记录仪集成。所提出的口袋大小的EEG记录器将足够小，以便在日常活动中相对不显眼地佩戴。这将允许该设备用于动态癫痫监测应用，并将为便携式EEG记录仪创造更大的市场。研究人员进行纵向脑电图调查将受益于共享市场与门诊癫痫监测，因为降低了生产成本。阿尔茨海默病（AD）是一种与年龄相关且不可逆转的脑部疾病，会在数年内发展。AD症状通常在65岁之后首次出现，并且是纵向研究的主题。最近，人们对使用脑电图（EEG）来筛查患者并识别AD的最初体征产生了兴趣。有大量文献报道了定量脑电图（QEEG）随年龄的变化以及变化幅度与进行性痴呆临床恶化程度之间的关系。EEG的使用为MRI和PET等更复杂的工具提供了低成本的替代方案，以区分指示未来问题的脑功能和解剖学特征。建议的微型便携式脑电图记录仪，易于应用的干电极技术，可以应用在家里收集数据的纵向调查的老年人。