Training in Translational Research of Lung, Head and Neck Cancer

肺癌、头颈癌转化研究培训

• 批准号: 9404554
• 负责人: Xiao-Jing Wang
• 金额: $ 0.89万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9404554
• 关键词: Head and Neck Cancer; Lung; Training; Translational Research

DESCRIPTION (provided by applicant): The poor prognosis of lung cancer and head and neck cancer has not improved in the past three decades; both are largely tobacco associated. The University of Colorado Cancer Center (UCCC) has a Lung, Head and Neck cancer (LHN) Program with the overall goal of translating scientific research discoveries into preventive and therapeutic interventions to decrease the incidence and mortality of LHN cancers. This application proposes program-wide training, which will best utilize resources and expertise to train the next-generation of basic- and physician-scientists dedicated to LHN research. Based on the NCI's postdoctoral/predoctoral ratio requirement of, we propose to appoint 3 new postdocs and 1 new predoctoral student per award year. The total of 29 training faculty members are selected from active members of UCCC based on their scientific/clinical expertise and track records of mentorship to achieve training of translational LHN research. These faculty members are from both basic science and clinical departments. In addition to laboratory training, we have designed mandatory didactic coursework for all trainees and clinical coursework for non-MD trainees to enhance the trainee's scientific background and the translational aspect of our program. Our specific goal is that the program's trainees will acquire the professional skills for productive academic careers in basic and translational LHN research. We will vigorously select trainees from external and internal trainee pools based on their academic records and commitments to LHN research.

描述（申请人提供）：近三十年来肺癌、头颈癌预后不佳的状况没有改善；两者都主要与烟草有关。科罗拉多大学癌症中心（UCCC）有一个肺、头颈癌（LHN）项目，其总体目标是将科学研究发现转化为预防和治疗干预措施，以降低LHN癌症的发病率和死亡率。该申请提出了项目范围内的培训，这将最好地利用资源和专业知识来培训下一代致力于LHN研究的基础科学家和内科科学家。根据NCI的博士后/博士学位比例要求，我们建议每奖励年度新任命3名博士后和1名博士生。根据UCCC的科学/临床专业知识和指导记录，共有29名培训教师从UCCC的活跃成员中选出，以实现转化性LHN研究的培训。这些教员来自基础科学和临床科室。除了实验室培训，我们还为所有学员设计了强制性的教学课程，并为非医学博士学员设计了临床课程，以增强学员的科学背景和我们项目的转化方面。我们的具体目标是，该计划的学员将获得在基础和转化LHN研究中富有成效的学术生涯的专业技能。我们将根据学员的学习成绩和对LHN研究的承诺，从外部和内部学员中大力选拔学员。