Long-term physical exercise improves cognitive performance through neuroimmune modulation

长期体育锻炼通过神经免疫调节提高认知能力

• 批准号: nhmrc : 1043771
• 负责人: Prof Bernhard Baune
• 金额: $ 32.91万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/long-term-physical-neuroimmune-modulation/111602
• 关键词: Long; term; physical; exercise; improves

This research investigates for how long exercise needs to carried out in order to be beneficial for cognitive function. We choose an animal model which simulates chronic brain inflammation as seen during aging processes of humans and during many inflammatory diseases affecting brain function. This research will unravel the long-term immunomodulatory and protective effects of exercise on brain function as well as the short-term anti-inflammatory effects on brain function.

这项研究调查了锻炼需要多长时间才能对认知功能有益。我们选择了一种动物模型来模拟人类衰老过程中的慢性脑炎症以及许多影响脑功能的炎症性疾病。本研究将揭示运动对脑功能的长期免疫调节和保护作用以及对脑功能的短期抗炎作用。