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Clinical Trials Network: The Texas Node

临床试验网络：德克萨斯节点

基本信息

批准号：
9385611
负责人：
MADHUKAR H. TRIVEDI
金额：
$ 58.18万
依托单位：
UT SOUTHWESTERN MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-06-01 至 2017-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9385611
关键词：
Academy Address Adolescent Alcohol or Other Drugs use American Analgesics Ancillary Study Area Caring Chinese People Clinic Clinical Clinical Research Clinical Trials Clinical Trials Network Collaborations Communities Community Physician Comorbidity Early Intervention Early identification Educational workshop Electronic Health Record Ensure Evidence based practice Exercise Expenditure Family Physicians Federally Qualified Health Center Foundations Funding Funding Mechanisms Future Genetic Genetic study Grant Health Personnel Health Sciences Health Services Health system Healthcare Hispanics Home environment Hospitals Individual Information Systems Institutes Intervention K-Series Research Career Programs Knowledge Leadership Literature Measurement Medical Medical Records Medical center Mental Depression Mental disorders Mentors Methods Minority National Institute of Drug Abuse Organizational Change Outpatients Patient-Focused Outcomes Pediatric Hospitals Performance Persons Pharmacotherapy Physicians Population Primary Health Care Provider Psychiatry Publications Research Research Institute Research Personnel Residencies Risk Scientist Secure Services Site Solid Substance Use Disorder System Technology Texas Training Training Activity Translational Research Universities Veterans Work addiction base candidate selection care systems career development chronic pain experience improved innovation interest medical specialties member metropolitan multi-site trial novel novel strategies patient oriented patient population practice-based research network primary care setting programs public health relevance safety net screening secondary analysis substance misuse symposium training opportunity treatment center treatment program

项目摘要

DESCRIPTION: This is a competing renewal application to continue funding the Texas Node (TxN) of the NIDA Clinical Trials Network (CTN). During the previous funding period the TxN, based at the University of Texas Southwestern Medical Center in Dallas, made substantial contributions to CTN research, the scientific literature, and dissemination and training activities TxN study sites were top performers across the 8 CTN trials implemented. TxN scientists developed and led three studies: the first large study to evaluate exercise as a novel intervention for stimulant use, a genetics study, and a study using electronic health records (EHRs). Outstanding contributions to the field were made, with 38 publications and 57 presentations. Over 300 addiction treatment providers were trained in several evidence-based practices via annual workshops hosted by the TxN. Scientists mentored junior investigators, resulting in funded grants and publications. Changes made to increase efficiency, decrease expenditures, and continually improve performance during the previous funding period have uniquely prepared the TxN to perform superbly during the next period. This renewal application capitalizes on over 20 years of experience of the PI, Madhukar H. Trivedi, MD, and the experiences of other key investigators through its emphasis on primary care networks, large systems of care, and use of EHRs to positively impact substance use. Building on the TxN's solid foundation of collaborating with specialty addiction community treatment programs, additional partnerships have been secured with healthcare networks that provide access to varied patient populations throughout Texas and the US. These networks are excited to work with the TxN and the CTN. Partners include one of the largest adolescent outpatient primary care networks in the US, one of the largest safety net hospital systems in the US, and the American Academy of Family Physicians National Research Network. Other important collaborating groups include the national VA Substance Use Disorder - Quality Enhancement Research Initiative, Patient Centered Outcomes Research Institute's Greater Plains Collaborative, and the National Center for Advancing Translational Sciences Accrual for Clinical Trials. The TxN research agenda, which focuses on early identification and intervention, is consistent with the CTN's priorities, addresses clinical needs identified by node partners, and capitalizes on expertise in the TxN. The TxN aims to answer questions of critical importance to the field by utilizing innovative interventions as well as EHR- and other technology-based methods, at the point of primary care, to significantly improve the care of persons who misuse substances.