Translational Research Activities in Neuropsychiatry (TRAIN) - Renewal - 1

项目总结 神经科学方法、技术和分析的快速发展，以了解 病理生理学和精神疾病的治疗取得了重大进展，成为一种强有力的 将尖端研究转化为针对精神疾病的个性化治疗。在……里面 为了更好地利用这些进步，精神病学的下一代研究人员 接受将转化性研究与临床培训相结合的重点培训。精神科训练 提供这一重点的课程，以及专门的研究时间、领导力和相关技能 发展，是非常需要的。虽然人们对医生严重短缺的问题感到担忧- 在科学家正在接受培训的同时，也有理由乐观，因为医学/博士医学院校的数量 申请精神科住院医生职位的毕业生有所增加。我们的临床和转化性研究培训 计划，神经精神病学的翻译研究活动(TRAIN)旨在提供特殊的 对精神病学住院医师的培训和指导，明确的目标是产生临床和翻译 精神病学的研究人员，他们将成为独立的内科科学家。本节目的重点是 潜在遗传学和神经生物学的破坏之间的关系以及它们与适应性的关系 行为，如在NIMH研究领域标准(RDoC)框架中，以及 可以为临床护理提供信息的生物标志物。培训计划利用专业知识并处理我们的 教职员工的工作是弥补该领域现有的差距。这包括关键内容方面的重点工作和专业知识 地区、人口和环境，以及跨所有翻译科学范围的方法的使用 从法官到社区。我们的结构化计划提供了卓越的指导计划， 为参与的居民提供体验机会，并适时授课。列车计划是 专门为培训下一代研究人员而设计，以便他们能够将神经科学和 遗传学研究对我们对广泛的精神健康问题和 治疗。Train促进了翻译研究所需的团队科学指导和培训， 强调通过实施有指导的研究项目以及交付成果来提高生产率 如建立网络和制定供资建议，使受训人员具备下一步的培训和 学术研究。培训还注重健康和防止疲惫，以鼓励及早 采取自我护理，增强复原力。

PROJECT SUMMARY Rapid developments in neuroscientific approaches, technologies, and analytics to understand the pathophysiology and treatment of mental illnesses have resulted in major advances that serve as a strong base toward the translation of cutting-edge research into personalized treatments for psychiatric conditions. In order to best leverage these advances, it is imperative that the next generation of researchers in psychiatry receive focused training that integrates translational research with clinical training. Psychiatric training programs that provide this focus, in conjunction with dedicated research time, and leadership and related skill development, are greatly needed. While there is concern in the field of a profound shortage of physician- scientists being trained, there is also reason for optimism, in that the number of MD/PhD medical school graduates applying for psychiatric residencies has increased. Our clinical and translational research training program, Translational Research Activities In Neuropsychiatry (TRAIN) is designed to provide exceptional training and mentoring to psychiatry residents with the express goal of generating clinical and translational researchers in psychiatry who will go on to become independent physician-scientists. This program focuses on the relationship between disruptions in underlying genetics and neurobiology and how they relate to adaptive behavior, as in the NIMH Research Domain Criteria (RDoC) framework, as well as the emergence of biomarkers that can inform clinical care. The TRAIN program harnesses the expertise and processes our faculty employ to bridge existing gaps in the field. This includes focused work and expertise in critical content areas, populations, and settings, as well as the use of approaches that span all ranges of translational science from the bench to the community. Our structured program provides an exceptional mentoring plan with experiential opportunities to participating residents coupled with timely didactics. The TRAIN program is specifically designed to train the next generation of researchers so that they can translate neuroscience and genetics research into advancements of our understanding of a wide range of mental health problems and treatments. TRAIN facilitates team science mentoring and training that is needed for translational research, with an emphasis on productivity through the conduct of a mentored research project, as well as deliverables such as networking and development of funding proposals to equip trainees for their next steps in training and academic research. TRAIN also focuses on wellness and guarding against burnout to encourage early adoption of self-care and enhance resilience.