Translational Research Activities in Neuropsychiatry (TRAIN)

神经精神病学转化研究活动（TRAIN）

• 批准号: 9321772
• 负责人: MADHUKAR H. TRIVEDI
• 金额: $ 19.98万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-10 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9321772
• 关键词: Achievement; Adaptive Behaviors; Address; Area; Behavior; Behavior Therapy; Behavioral; Biological; Biology; Clinical; Clinical Research; Cognition; Coupled; Department chair; Development; Doctor of Philosophy; Education; Electroencephalography; Emerging Technologies; Epigenetic Process; Funding; Future; Genetic; Genetic Research; Goals; Grant; Heart; Identity Crisis; Institute of Medicine (U.S.); Institution; Instruction; Lead; Leadership; Medical center; Medicine; Mental Health; Mental disorders; Mentors; Mentorship; Mind; National Institute of Mental Health; Neurobiology; Neurosciences; Neurosciences Research; Physicians; Principal Investigator; Proteomics; Psychiatrist; Psychiatry; Recruitment Activity; Research; Research Activity; Research Domain Criteria; Research Infrastructure; Research Personnel; Research Training; Residencies; Resources; Role; Science; Scientist; Structure; Students; Technology; Time; Training; Training Programs; Translating; Translational Research; base; career; design; faculty mentor; leadership development; medical schools; medical specialties; meetings; neuroimaging; neuropsychiatry; next generation; novel strategies; optimism; programs; psychogenetics; public health relevance; skill acquisition; success; translational scientist; trend

DESCRIPTION (provided by applicant): Advances in neuroscience, genetics, and the understanding of the biology of behavior have provided an opportunity to make profound advancements in understanding and treating mental illnesses. In order to take advantage of these advances, the next generation of researchers in psychiatry will need focused training that integrates translational research with clinical/behavioral training. While there is concern in the field of profound shortage of physician-scientists being trained (Yager et al., 2004; Fenton et al. 2004; "Psychiatry's Identity Crisis" 2012), there is also reason for optimism, in that the number of MD/PhD medical school graduates applying for psychiatric residencies has increased. Federal research monies have increased substantially to psychiatry departments over the last few decades, and yet, the percentage of psychiatrists with adequate research training, dedicated research time, and leadership roles (e.g., Principal Investigator) on funded grants lags well behind other areas of medicine (Kupfer et al., 2002). In order to address these needs, we are requesting support for the development of a translational clinical research training program. The Translational Research Activities In Clinical Neuroscience (TRAIN) program is designed to provide exceptional training and mentoring to psychiatry residents with the express goal of generating clinical and translational researchers in psychiatry who will go on to become independent physician-scientists. This program will focus on the relationship between disruptions in underlying genetics and neurobiology and how they relate to adaptive behavior, as in the NIMH Research Domain Criteria (RDoC) framework. This program will provide psychiatry residents training and mentorship from nationally recognized translational researchers in psychiatry. The program includes faculty mentors at UT Southwestern with active research programs, as well as meetings and instruction by nationally recognized researchers at other institutions. The program is also designed to reach out to students in training to recruit th best minds to become clinical researchers.

描述（由申请人提供）：神经科学，遗传学和行为生物学的理解的进步提供了一个机会，使理解和治疗精神疾病的深刻进步。为了利用这些进步，下一代精神病学研究人员将需要集中培训，将转化研究与临床/行为培训相结合。虽然在该领域存在着严重缺乏正在接受培训的医生-科学家的问题（Yager等人，二○ ○四年;芬顿等人，2004年;“精神病学的身份危机”，2012年），也有理由乐观，因为申请精神病学住院医师的医学博士/博士毕业生人数有所增加。在过去的几十年里，联邦精神病学部门的研究资金大幅增加，然而，接受过足够研究培训、投入专门研究时间和领导角色（例如，主要研究者）的赠款远远落后于其他医学领域（Kupfer等人，2002年）。为了满足这些需求，我们正在请求支持开发转化临床研究培训计划。临床神经科学转化研究活动（TRAIN）计划旨在为精神病学居民提供特殊的培训和指导，其明确目标是培养精神病学的临床和转化研究人员，他们将继续成为独立的医生科学家。该计划将专注于基础遗传学和神经生物学的破坏之间的关系，以及它们如何与适应行为相关，如NIMH研究领域标准（RDoC）框架。该计划将提供精神病学居民培训和指导，从国家认可的精神病学翻译研究人员。该计划包括UT西南部的教师导师，他们有积极的研究计划，以及其他机构的国家认可的研究人员的会议和指导。该计划还旨在接触培训学生，以招募最优秀的人才成为临床研究人员。