Research Training in Nephrology

 描述(由申请者提供)：这是波士顿大学肾病学培训补助金的竞争性续签。这一充满活力和成功的计划已经持续活跃了41年。它的主要目标是确定、激励和培训有前途的博士后候选人，从事专注于肾脏疾病的翻译研究职业，并帮助合格的受训人员获得合适的研究职位。该计划旨在为准备从事学术肾病学工作的医生提供成功研究所必需的全面的科学基础，并吸引新近毕业的博士，为他们提供肾脏相关研究的博士后培训。培训与NCATS咨询委员会工作组的建议密切一致，为下一代生物医学科学家的翻译研究职业生涯做好准备。研究培训将继续在 至少两年。平均每年将有三名新学员进入该项目。培训的主要机制是在由9名肾病学家和5名基础科学家组成的一名或多名培训人员的亲自监督下直接进行研究。优秀的跨学科培训人员提供有关自身免疫、缺血性和中毒性肾损伤、免疫病理学、与肾癌和发育生物学相关的基因调控、慢性肾脏疾病的血管疾病和血栓形成以及与肾脏疾病相关的心血管临床流行病学方面的翻译培训。良好的合作安排使每个受训人员能够获得广泛的研究经验，并将各种技能集中在特定的研究方案上。受训者对实验的设计、实施和解释承担分级责任，逐渐变得更加独立。所有实习生和工作人员经常会面，参加丰富的研讨会、日记俱乐部和其他正式的集体教学练习。获得转化医学和分子医学博士学位的课程是可用的，临床研究的正式培训是通过不列颠哥伦比亚大学公共卫生学院提供的。受训人员在埃文斯生物医学研究中心现代化、设备齐全的实验室和基础科学学院的实验室工作。这些设施靠近核心设施、由全职兽医监督的现代动物保育区和BUSPH。在整个培训期间，强调协作和团队建设。在这次更新中，我们利用了波士顿大学医学院在生物信息学、职业发展、评估、网络和跟踪计划方面取得的实质性进展，以增强实验室或研究数据库以外的培训体验。由教务长办公室支持的博士后事务办公室以及发展与多样性和跨学科研究项目增加了培训环境的丰富性，并有助于促进健康的工作/生活平衡。

 DESCRIPTION (provided by applicant): This is a competitive renewal of the nephrology training grant at Boston University. This vibrant and successful program has been active continuously for 41 years. Its primary goals are to identify, inspire and train promising postdoctoral candidates for translational research careers focused on kidney diseases and to assist qualified trainees in obtaining suitable research positions. The program is designed to provide physicians heading for careers in academic nephrology the thorough scientific grounding necessary for a successful research career and to attract recent PhD graduates and provide them postdoctoral training in kidney-related research. Training is closely aligned with the NCATS Advisory Council Working Group recommendations to prepare the next generation of biomedical scientists for translational research careers. Research training will continue for at least two years. On average, three new trainees will enter the program each year. The principal mechanism for training is direct performance of research under the personal supervision of one or more of the training staff comprised of nine nephrologists and five basic scientists. Outstanding, interdisciplinary training staff provides translational training in autoimmunity, ischemic and toxic renal injury, immunopathology, gene regulation related to renal cancer and developmental biology, and vascular disease and thrombosis in chronic kidney disease and clinical epidemiology of cardiovascular relevant to kidney diseases. Well-established collaborative arrangements allow each trainee to acquire a broad research experience and focus a variety of skills on a specific research protocol. Trainees assume graded responsibility for the design, conduct and interpretation of experiments, progressively becoming more independent. All trainees and staff meet frequently for a rich menu of seminars, journal clubs and other formal group teaching exercises. Coursework leading to a PhD in Translational and Molecular Medicine is available, and formal training in clinical research is provided through the BU School of Public Health. Trainees work in a modern, well-equipped laboratory in the Evans Biomedical Research Center and laboratories of basic science faculty. These are in close proximity to core facilities, modern animal care quarters supervised by a full-time veterinarian, and the BUSPH. Collaboration and team building are emphasized throughout the training period. In this renewal we have taken advantage of substantial progress on the BU medical campus in bioinformatics, career development, evaluation, networking and tracking programs to enhance the training experience beyond the laboratory bench or research database. An Office of Postdoctoral Affairs supported by the Provost's office, and programs in Development and Diversity and Interdisciplinary Research add to the richness of the training environment and help promote a healthy work/life balance.