Research Training in Pediatric Nephrology

小儿肾脏病学研究培训

• 批准号: 9070063
• 负责人: CARLTON MATTHEW BATES
• 金额: $ 25.73万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9070063
• 关键词: Childhood; Nephrology; Research Training

 DESCRIPTION (provided by applicant): This renewal application seeks to sustain NIH funding to train pediatric nephrology fellows at the University of Pittsburgh/Children's Hospital of Pittsburgh of UPMC to become successful clinician scientists. Few pediatric nephrologists have active R01 grants and few Pediatric Nephrology Divisions have multiple NIH funded faculty. Furthermore, there are few dedicated pediatric nephrology T32 training grant positions available to train fellows. Given current financial difficulties, it has also been difficult for Medical Schols and Departments of Pediatrics to commit resources to training fellows to do research. Taken together, there are often inadequate resources and few mentors available to train pediatric nephrologists to do basic, translational, or clinical research. The resulting paucity of pediatric nephrology fellows that develop successful careers in research significantly impedes progress in deciphering pathophysiology and treatments for kidney diseases that affect children (and subsequently adults). The objective of this program has been to train pediatric nephrology fellows to become clinician researchers. Through the first four years of the program, we have trained six fellows, including an underrepresented minority, all of whom are moving in academic positions and many of whom have (or are planning to have) significant research programs. We are seeking to renew the currently funded three positions for PGY5 or PGY6 pediatric nephrology fellows and to add a fourth position that could be used for training medical fellows or PhD postdoctoral fellows. This training program is uniquely positioned in that there are five (soon to be six) externally-funded Pediatric Nephrology faculty members (two of which are currently qualified to be mentors, which will increase as junior faculty research programs mature). This is one of the largest Pediatric Nephrology divisions in the country with ten (soon to be 11) MD and PhD faculty and a robust clinical program that has enhanced fellow recruitment. There are also several potential mentors outside of the Pediatric Nephrology Division at the University of Pittsburgh that have significant track records of NIH funding. Moreover, the University of Pittsburgh ranks in the top five for NIH awards obtained from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The proposed faculty mentors in this program also have had a significant track record of mentoring post-doctoral trainees. The research areas are very diverse and include mentors focused on basic, translational, and/or clinical research. The environment is also very supportive and includes coursework and optional degrees for fellows (e.g. Fundamentals of Biomedical Science courses for basic research and Certificates in Clinical Research and Masters in Clinical Research, Public Health, and Bioethics for clinical/translational research). The training program is also very focused on increasing the diversity of trainees and on education regarding the responsible conduct of research. In summary, the breadth of the research opportunities, emerging training track record, and outstanding environment make this institution an excellent place to train pediatric nephrology fellows to become clinician scientists.

 描述（由申请人提供）：此更新申请旨在维持NIH的资金，以培训匹兹堡大学/UPMC匹兹堡儿童医院的儿科肾脏病学研究员，使其成为成功的临床科学家。很少有儿科肾病学家有活跃的R 01赠款，很少有儿科肾病部门有多个NIH资助的教师。此外，有几个专门的儿科肾脏病T32培训补助金的位置，可用于培训研究员。鉴于目前的财政困难，医学院和儿科系也很难投入资源培训研究员进行研究。总的来说，通常没有足够的资源和导师来培训儿科肾病学家进行基础，转化或临床研究。由此导致的儿科肾病研究员的缺乏，发展成功的职业生涯在研究中显着阻碍了破译的病理生理学和肾脏疾病的治疗，影响儿童（以及随后的成人）的进展。该项目的目标是培养儿科肾病学研究员成为临床研究人员。通过该计划的前四年，我们已经培训了六名研究员，其中包括代表性不足的少数民族，他们都在学术职位上移动，其中许多人有（或计划有）重要的研究项目。我们正在寻求更新目前资助的三个职位，为pgy 5或pgy 6儿科肾病研究员，并增加第四个职位，可用于培训医学研究员或博士博士后研究员。该培训计划的独特之处在于，有五名（即将成为六名）外部资助的儿科肾病教师（其中两名目前有资格成为导师，随着初级教师研究计划的成熟，这将增加）。这是全国最大的儿科肾脏病部门之一，有10个（即将 拥有医学博士和博士学位的教师，以及一个强大的临床项目，这增加了研究员的招募。匹兹堡大学儿科肾病科之外还有几位潜在的导师，他们有着大量的NIH资助记录。此外，匹兹堡大学在国家糖尿病、消化和肾脏疾病研究所（NIDDK）颁发的NIH奖项中排名前五。该计划中拟议的教师导师也有指导博士后学员的重要记录。研究领域非常多样化，包括专注于基础，转化和/或临床研究的导师。环境也非常支持，包括课程和研究员的可选学位（例如，基础研究的生物医学科学基础课程和临床研究证书和临床研究硕士，公共卫生和临床/转化研究的生物伦理学）。培训计划还非常注重增加受训人员的多样性和关于负责任地开展研究的教育。总之，研究机会的广度，新兴的培训记录和优秀的环境使该机构成为培训儿科肾脏病学研究员成为临床科学家的绝佳场所。