Effect of Banning Menthol Flavorant on Cigarette and e-Cigarette Use

禁止薄荷醇香料对卷烟和电子烟使用的影响

• 批准号: 9439149
• 负责人: MICHAEL KOTLYAR
• 金额: $ 11.49万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9439149
• 关键词: Address; Affect; Behavior; Candy; Characteristics; Cigarette; Cigarette Smoker; Data; Electronic cigarette; Event; Family Smoking Prevention and Tobacco Control Act; Flavoring; Fruit; Future; Lead; Measures; Menthol; Motivation; Nicotine; Participant; Pattern; Pilot Projects; Policies; Public Health; Randomized; Regulation; Reporting; Research; Research Priority; Smoke; Smoker; Smoking; Surveys; Tobacco; Tobacco use; Toxicant exposure; United States Food and Drug Administration; Visit; Work; authority; base; cigarette smoking; innovation; response; smoking cessation; uptake; vaping

Project Summary Following the passage of the Family Smoking Prevention and Tobacco Control Act, the United States Food and Drug Administration (FDA) banned cigarettes flavored with fruit or candy, but specifically excluded menthol from this ban. With the FDA recently extending its authority to electronic cigarettes (i.e., e-cigarettes), the ability to enact regulations regarding the availability of flavorants (including menthol) will extend to these products as well. As there is limited information currently available on how menthol flavoring in e-cigarettes affects overall tobacco use, there is little scientific basis available upon which to formulate regulations regarding menthol flavorant in non-cigarette forms of tobacco. The proposed study will obtain preliminary information regarding how a menthol ban that either exempts or includes e-cigarettes is likely to affect overall tobacco use. In this study, menthol cigarette smokers will over a 6 week period be assigned to one of three conditions: 1) a condition simulating a ban on menthol cigarettes but not menthol e-cigarettes; 2) a condition simulating a ban on both menthol cigarettes and menthol e-cigarettes; and 3) a condition in which menthol is not banned for either product (i.e., the control condition). Participants will be able to use any products that are available in their randomization group and all participants will have medicinal nicotine available should they decide to quit tobacco products entirely. Over the six week period, tobacco product use, motivation to quit, number of quit attempts, and support for a menthol ban will be assessed. Data from this pilot study will be used to plan larger studies examining how menthol flavor in e-cigarettes affects tobacco product use patterns and toxicant exposure among smokers. This work is innovative as previous studies have not evaluated the impact of regulating menthol in cigarettes while exempting e-cigarettes. It is significant in that it begins to provide a scientific base for evaluating if menthol flavoring in e-cigarettes should be regulated differently than in cigarettes.

项目概要 随着《家庭吸烟预防和烟草控制法案》的通过，美国食品 和药物管理局 (FDA) 禁止销售带有水果或糖果口味的香烟，但明确排除薄荷醇 从这个禁令。随着 FDA 最近将其权限扩大到电子烟（即电子烟）， 制定有关香料（包括薄荷醇）可用性的法规的能力将扩展到这些 产品也是如此。由于目前有关电子烟中薄荷醇调味剂的信息有限 影响整体烟草使用，制定法规缺乏科学依据 关于非卷烟形式的烟草中的薄荷醇香料。拟议的研究将获得初步 有关豁免或包括电子烟​​的薄荷醇禁令可能如何影响整体的信息 烟草的使用。在这项研究中，薄荷醇卷烟吸烟者将在 6 周内被分配到以下三个组之一： 条件：1）模拟薄荷醇卷烟禁令但不模拟薄荷醇电子烟的条件； 2）条件 模拟薄荷醇香烟和薄荷醇电子烟的禁令； 3) 薄荷醇存在的情况 这两种产品均未禁止（即控制条件）。参与者将能够使用任何产品 在他们的随机分组中可用，并且所有参与者都将有药用尼古丁，如果他们 决定完全戒掉烟草制品。在六周期间，烟草产品的使用、戒烟动机、 将评估戒烟尝试的次数以及对薄荷醇禁令的支持。该试点研究的数据将用于 计划更大规模的研究，探讨电子烟中的薄荷味如何影响烟草产品的使用模式，以及 吸烟者中的毒物暴露。这项工作具有创新性，因为之前的研究尚未评估其影响 监管香烟中的薄荷醇，同时豁免电子烟。其意义重大在于它开始提供 评估电子烟中薄荷醇调味剂是否应采用与电子烟中薄荷醇调味剂不同的监管方式的科学依据 香烟。