Administrative Core

摘要 行政核心（核心A）将提供所有科学、管理、后勤、 和财务监督，以促进和协调本报告所述的研究 程序.集中化管理对于有效协调、管理 执行每一个项目。行政核心将确保成人学习 艾滋病毒（项目1），儿科艾滋病毒研究（项目2），临床前非人灵长类动物 (NHP)数学建模和生物信息学核心（核心B） 遵守这些章节中描述的时间表和交付成果。 行政核心将组织每月两次的电话会议，并定期在- 研究者之间的人员会议，与临床研究中心的接口，维护 所有临床前的监管批准，提供财务和后勤监督，管理 分包合同，并协调与科学顾问委员会和DAIDS的会议 方案官员。这种详细的行政和管理结构将确保 所有的研究都集中在促进发展的总体目标上， 对艾滋病毒反弹的认识

ABSTRACT The Administrative Core (Core A) will provide all scientific, managerial, logistic, and financial oversight to facilitate and to coordinate the studies described in this program. Centralized administration is critical for efficient coordination, management and execution each project. The Administrative Core will ensure that the Adults studies of HIV (Project 1), Pediatric HIV studies (Project 2), the preclinical non-human primate (NHP) studies (Project 3), the Mathematical Modeling and Bioinformatics Core (Core B) adhere to the timelines and deliverables described in those sections. The Administrative Core will organize twice-monthly conference calls and regular in- person meetings among the investigators, interface with clinical sites, maintain regulatory approvals for all preclinical, provide fiscal and logistic oversight, manage subcontracts, and coordinate meetings with the Scientific Advisory Board and DAIDS Program Officials. This detailed administration and management structure will ensure that all the studies remain focused on the overall objective of advancing the understanding of HIV rebound