2019 Inhibition in the CNS Gordon Research Conference and Gordon Research Seminar

项目摘要 2019年关于中枢神经系统抑制的戈登研究会议（GRC）将在 2019年7月7日至12日，美国缅因州纽里星期日河的Grand Summit酒店。这项国际研究 自2005年以来，作为GRC系列会议的一部分，每两年举行一次会议。它将在 2019年7月6日至7日，与以前的版本一样，由戈登研究研讨会（GRS），这是保留给 研究生和博士后，以便给他们介绍了GRC的主要议题。 抑制主要由神经递质GABA介导，调节中枢神经系统的各个方面 (CNS)功能，并代表了治疗的主要目标。科学界致力于抑制 神经传递是广泛和动态的。这个GRC提供了一个重要的论坛，将领导者聚集在一起， 这个领域沿着的是早期职业调查员中冉冉升起的新星。这次会议的目标是增加 我们对分子、突触和网络机制的理解有助于 在正常和异常CNS功能中抑制神经传递。为实现这一目标，会议将 追求特定的目标，包括传播有关大脑功能抑制的最新发现 和功能障碍，促进多样性和领域内的合作，并推进培训， 研究生和博士后研究员。这些目标将通过召集34位世界级的演讲者来实现 和9名讨论负责人，他们来自3个国家的11个不同国家， 来自世界各大洲（25名来自美国; 20名女性），确保国际性和多样性。集选区将容纳 在一个与世隔绝的环境中举行的为期五天的会议上，此应用程序的健康相关性是 在CNS GRC/GRS会议中的抑制讨论将定义需要 在认知、发育和各种神经学和 涉及抑制失调的精神障碍，包括自闭症、癫痫、精神分裂症、焦虑， 抑郁症和其他疾病。总的来说，预计科学讨论，研究会谈， 海报会议，以及本次会议不同参与者之间的各种非正式互动将 促进我们对中枢神经系统功能和人类疾病的基本机制的理解。

Project Summary The 2019 Gordon Research Conference (GRC) on Inhibition in the Central Nervous System will be held at the Grand Summit Hotel at Sunday River, Newry, Maine, USA, on July 7-12, 2019. This international research conference has been held every 2 years since 2005 as part of the GRC conference series. It will be preceded on July 6 -7, 2019, as in previous editions, by the Gordon Research Seminar (GRS), which is reserved for graduate students and postdocs in order to give them an introduction to the main topics of the GRC. Inhibition, mediated primarily by the neurotransmitter GABA, regulates all aspects of central nervous system (CNS) function and represents a major target for therapeutics. The scientific community working on inhibitory neurotransmission is broad and very dynamic. This GRC provides a major forum bringing together leaders in the field along with rising new stars among early-career investigators. The goal of this meeting is to increase our understanding of the molecular, synaptic and network mechanisms contributing to the critical role of inhibitory neurotransmission in normal and abnormal CNS function. To achieve this goal, the meeting will pursue specific aims that include dissemination of the latest discoveries about inhibition in brain function and dysfunction, promotion of diversity and collaboration within the field, and advancement of the training of graduate students and postdoctoral fellows. These aims will be met by convening 34 world-class speakers and 9 discussion leaders actively working in diverse areas of inhibition from 11 different countries across 3 continents (25 from the US; 20 women), ensuring internationality and diversity. The GRC will accommodate up to 200 participants at a five-day conference in an isolated setting. The health relatedness of this application is that discussions at the Inhibition in the CNS GRC/GRS meetings will define the questions that require experimental resolution in areas related to cognition, development, and a variety of neurological and psychiatric disorders that involve dysregulated inhibition including autism, epilepsy, schizophrenia, anxiety, depression and other diseases. Taken together, it is expected that the scientific discussions, research talks, poster sessions, and various informal interactions between the diverse participants of this conference will advance our understanding of fundamental mechanisms underlying in CNS function and human disease.