Family-based eHealth Obesity Prevention Intervention for Hispanic Adolescents

项目摘要/摘要 这份为期五年的K01申请的目的是为Sara M.St.George博士的独立研究做准备 致力于开发、评估和传播创新的循证肥胖预防 针对西班牙裔青少年的干预措施。该项目包含三个培训目标：1)提拔圣彼得堡大学圣彼得堡分校博士。 乔治对导致西班牙裔肥胖和相关健康行为的文化因素的理解 青少年；2)发展她在设计行为干预技术方面的专业知识(即 使用移动电话等技术促进行为改变)，包括使用人类 因素/以用户为中心的设计方法，将用户观点纳入干预开发；以及 3)提高圣乔治博士应用先进的定量方法评估随机 对照试验。为了实现这些目标，圣乔治博士组建了一个跨学科的指导团队 拥有公共卫生、心理学、人为因素工程学、行为干预技术和 数量化方法。鉴于#年以家庭为基础的肥胖预防干预研究的匮乏 西班牙裔青少年以及数据表明拉美裔美国人最有可能从 对于智能手机，圣乔治博士的研究将专注于开发和试点一种基于家庭的干预 使用网络和移动电话(EHealth)来改善身体活动、久坐行为和饮食 西班牙裔青少年。提出了两个研究目标：1)进行形成性研究，这将为 以家庭为基础的电子健康肥胖预防干预措施的开发 西班牙裔青少年的体力活动、久坐行为和饮食摄入量；以及2)进行试点 随机试验，以确定干预的可行性、可接受性和初步效果。至 实现目标1，圣乔治博士将让西班牙裔父母和青少年参与设计的所有阶段 进程：1a)对20名西班牙裔父母和青少年进行四个重点小组；1b)发展和 对3组5名西班牙裔美国人反复测试干预的视觉模型(“纸质原型” 亲子二元；1c)开发全功能干预原型；1d)指导领域 使用全功能原型对10个西班牙裔父母-青少年二人进行试验。为了实现目标2，圣彼得堡博士。 乔治将从儿科初级保健诊所招募50名父母-青少年双亲，并将其随机分配到一个家庭- 基于电子健康的肥胖预防干预或初级保健作为通常的比较条件。它是 假设干预将是可行的、可接受的，并与以下情况相比显示有希望的效果 像往常一样进行初级保健，增加中等到剧烈的体力活动，减少久坐行为，以及 在干预后和6个月的随访中改善青少年的高质量膳食摄入量。父级中的更改 健康的生活方式行为和家庭功能将被评估为次要结果。数据将用于 争取R01资金进行大规模随机对照试验。

PROJECT SUMMARY/ABSTRACT The purpose of this five year K01 application is to prepare Dr. Sara M. St. George for an independent research career devoted to developing, evaluating, and disseminating innovative, evidence-based obesity prevention interventions for Hispanic adolescents. This project contains three training goals: 1) To advance Dr. St. George's understanding of cultural factors that contribute to obesity and related health behaviors in Hispanic adolescents; 2) To develop her expertise in the design of behavioral intervention technologies (i.e., those that use technologies such as mobile phones to promote behavior change), including the use of human factors/user-centered design approaches to incorporate user perspectives into intervention development; and 3) To enhance Dr. St. George's ability to apply advanced quantitative methods for evaluating randomized controlled trials. To achieve these goals, Dr. St. George has assembled an interdisciplinary mentoring team with expertise in public health, psychology, human factors engineering, behavioral intervention technology, and quantitative methods. Given the paucity of research on family-based obesity prevention interventions in Hispanic adolescents as well as data indicating Hispanics are most likely to access the internet from smartphones, Dr. St. George's research will focus on developing and pilot testing a family-based intervention that uses the web and mobile phones (eHealth) to improve the physical activity, sedentary behavior, and diet of Hispanic adolescents. Two research aims are proposed: 1) To conduct formative research which will inform the development of a family-based eHealth obesity prevention intervention for improving moderate-to-vigorous physical activity, sedentary behavior, and dietary intake in Hispanic adolescents; and 2) To conduct a pilot randomized trial to determine the feasibility, acceptability, and preliminary effects of the intervention. To accomplish Aim 1, Dr. St. George will involve Hispanic parents and adolescents in all stages of the design process by: 1a) conducting four focus groups with 20 Hispanic parents and adolescents; 1b) developing and iteratively testing visual mockups (“paper prototypes”) of the intervention with three groups of 5 Hispanic parent-adolescent dyads; 1c) developing a fully functional intervention prototype; and 1d) conducting a field trial with 10 Hispanic parent-adolescent dyads using the fully functional prototype. To accomplish Aim 2, Dr. St. George will recruit and randomize 50 parent-adolescent dyads from pediatric primary care clinics to a family- based eHealth obesity prevention intervention or a primary care as usual comparison condition. It is hypothesized that the intervention will be feasible, acceptable, and show promising effects compared to primary care as usual in increasing moderate-to-vigorous physical activity, reducing sedentary behavior, and improving quality dietary intake in adolescents at post intervention and a 6 month follow-up. Changes in parent healthy lifestyle behaviors and family functioning will be assessed as secondary outcomes. Data will be used to pursue R01 funding to conduct a large-scale randomized controlled trial.