Florida Regional Coordinating Center for the NINDS Stroke Trials Network

NINDS 中风试验网络佛罗里达地区协调中心

• 批准号: 9753385
• 负责人: JOSE G ROMANO
• 金额: $ 30.7万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9753385
• 关键词: Acute; Address; Agreement; Animal Model; Area; Blood; Blood Vessels; Brain; Caribbean region; Cerebrovascular Disorders; Clinic; Clinical; Clinical Research; Clinical Trials; Collaborations; Critical Care; DNA; Degree program; Education; Emergency Medicine; Emergency medical service; Endowment; Enrollment; Ensure; Fellowship; Florida; Funding; Future; Genomics; Geography; Goals; Health Sciences; Hispanics; Hospitals; Infrastructure; Institutes; Institution; Institutional Review Boards; Intervention; Intervention Studies; Investigation; Master of Science; Memory Loss; Mentors; Mentorship; Minority; Multicenter Studies; National Institute of Neurological Disorders and Stroke; Neurology; Neurorehabilitation; Neurosciences; Paralysed; Participant; Patients; Pediatric Hospitals; Pediatric Neurology; Phase; Population Heterogeneity; Positioning Attribute; Prevention; Private Hospitals; Privatization; Public Hospitals; Puerto Rico; Rare Diseases; Recovery; Registries; Rehabilitation therapy; Research; Research Personnel; Research Project Grants; Residencies; Resources; Science; Scientist; Secondary Prevention; Site; Stem cells; Stroke; Stroke prevention; Structure; Testing; Tissues; Training; Training Programs; Translational Research; United States National Institutes of Health; Universities; Work; Workforce Development; acute stroke; age related; biobank; care outcomes; career; career development; certificate program; community setting; data management; demographics; education resources; ethnic diversity; experience; human genomics; improved; medical schools; member; multidisciplinary; neurosurgery; next generation; novel; patient population; post stroke; pre-clinical; programs; recruit; skills; stroke intervention; stroke model; stroke rehabilitation; stroke therapy; stroke trials; success; telerehabilitation; translational scientist; working group

Florida Regional Coordinating Center for the NINDS Stroke Trials Network This proposal outlines the University of Miami's application to remain as the Florida Regional Coordinating Center (RCC) in the Stroke Trials Network (StrokeNet). The goals of the Florida RCC are to: a) provide a robust and efficient infrastructure to implement high-quality research clinical trials that address acute stroke treatment, prevention and recovery; b) leverage the internal and regional resources to enhance the Stroke Trials Network; c) train the next generation of stroke clinical and translational researchers. The Florida RCC encompasses a large network of participating acute stroke, rehabilitation and pediatric hospitals that span across Florida, to ensure robust enrollment of an ethnically diverse population that reflects the changing demographics of the US. Our stroke program has a successful track record of participating in numerous NINDS acute and secondary prevention stroke trials, and is involved in other NIH networks and coordinates multicenter studies. Through our participating sites, extended referral network and multidisciplinary expertise, we will build upon the close partnership with pre-hospital Emergency Services, Emergency Medicine, Vascular Neurosurgery, Interventional Neurology, Neuro-Critical Care, Pediatric Neurology and Neurorehabilitation, as well as on academic-public- private institutional collaborations, to enroll and manage potential study participants. We also have unique resources that we can bring to the network. Integrated collaboration among cutting edge researchers in the areas of preclinical stroke, stem cells, human genomics, biorepository, brain bank, and the Miami CTSI make us uniquely positioned to develop, propose and implement novel translational early phase projects. The large residency and fellowship training programs in Neurosciences, the multidisciplinary educational resources in the institution, and our track record of mentoring clinical researchers, position our center to effectively train stroke researchers in clinical and translational research through a structured mentored program. Over the past funding cycle we have been an outstanding StrokeNet member: we expanded the RCC representation across Florida by adding new outstanding sites, recruited well into StrokeNet trials, were a top performer in regulatory metrics, trained 3 StrokeNet scholars, participated in 3 working groups and committees, submitted new proposals to the Network, and were engaged in all aspects of the program. Therefore, we have the depth and breadth of expertise and resources to successfully function as a RCC in the StrokeNet.

NINDS卒中试验网络佛罗里达地区协调中心 该提案概述了迈阿密大学申请继续作为佛罗里达地区协调 中风试验网络（StrokeNet）中的RCC中心。佛罗里达RCC的目标是：a）提供一个强大的 和高效的基础设施，以实施高质量的研究临床试验，解决急性中风治疗， 预防和康复; B）利用内部和区域资源加强中风试验网络; c）培养下一代中风临床和转化研究人员。佛罗里达RCC包括一个 横跨佛罗里达的大型急性中风、康复和儿科医院网络， 确保种族多样化的人口的稳健登记，反映美国不断变化的人口统计。 我们的中风项目有参与许多NINDS急性和继发性的成功记录 预防中风试验，并参与其他NIH网络和协调多中心研究。通过我们 参与的网站，扩展的转诊网络和多学科的专业知识，我们将建立在密切的 与院前急救服务、急诊医学、血管神经外科、介入治疗 神经病学，神经重症监护，儿科神经病学和神经康复，以及学术-公共- 私人机构合作，招募和管理潜在的研究参与者。我们还有独特的 我们可以为网络带来的资源。前沿研究人员之间的综合合作， 临床前中风、干细胞、人类基因组学、生物储存库、脑库和迈阿密CTSI等领域的研究， 我们独特的定位，以开发，提出和实施新的翻译早期阶段的项目。大 住院医师和奖学金培训计划在神经科学，多学科教育资源， 机构，以及我们指导临床研究人员的跟踪记录，使我们的中心能够有效地训练中风 研究人员通过结构化的指导计划进行临床和转化研究。在过去的融资 在一个循环中，我们一直是StrokeNet的杰出成员：我们在佛罗里达州扩大了RCC的代表性 通过增加新的优秀网站，招募到中风试验，是一个最好的表现在监管指标， 培训了3名中风网络学者，参加了3个工作组和委员会，向联合国秘书长提交了新的建议， 网络，并参与了该计划的各个方面。因此，我们有深度和广度， 专业知识和资源，以成功地作为一个RCC在中风网络。