Florida Regional Coordinating Center for the NINDS Stroke Trials Network

NINDS卒中试验网络佛罗里达区域协调中心 这项提案概述了迈阿密大学继续担任佛罗里达地区协调中心的申请 中风试验网络(StrokeNet)中的中心(RCC)。佛罗里达RCC的目标是：a)提供强大的 和高效的基础设施，以实施针对急性中风治疗的高质量研究临床试验， 预防和康复；b)利用内部和区域资源加强中风试验网络； C)培养下一代中风临床和翻译研究人员。佛罗里达RCC包括一个 横跨佛罗里达州的参与急性中风、康复和儿科医院的大型网络，到 确保反映美国不断变化的人口结构的种族多元化人口的强劲入学。 我们的中风计划有成功的记录，参与了许多NINDS急性和继发性NINDS 他还参与了美国国立卫生研究院的其他网络，并协调多中心研究。通过我们的 参与网站，扩展的转介网络和多学科的专业知识，我们将在关闭的基础上 与院前急救服务、急救医学、血管神经外科、介入 神经学，神经危重护理，儿科神经学和神经康复，以及学术-公共- 私人机构合作，以登记和管理潜在的研究参与者。我们还有独一无二的 我们可以为网络带来的资源。尖端研究人员之间的集成协作 临床前中风、干细胞、人类基因组学、生物库、脑库和迈阿密CTSI等领域 美国在开发、提出和实施新的翻译早期项目方面具有独特的优势。大的 神经科学的住院医师和研究员培训计划，多学科教育资源 机构，以及我们指导临床研究人员的记录，使我们的中心能够有效地训练中风 研究人员通过结构化的指导计划参与临床和转化性研究。在过去的资金 Cycle我们一直是StrokeNet的杰出成员：我们在佛罗里达州扩大了RCC的代表处 通过增加新的优秀网站，这些网站被招募到StrokeNet试验中，在监管指标方面表现最好， 培训了3名StrokeNet学者，参加了3个工作组和委员会，向 网络，并参与了该计划的方方面面。因此，我们有深度和广度的 在StrokeNet中作为RCC成功发挥作用的专业知识和资源。

Florida Regional Coordinating Center for the NINDS Stroke Trials Network This proposal outlines the University of Miami's application to remain as the Florida Regional Coordinating Center (RCC) in the Stroke Trials Network (StrokeNet). The goals of the Florida RCC are to: a) provide a robust and efficient infrastructure to implement high-quality research clinical trials that address acute stroke treatment, prevention and recovery; b) leverage the internal and regional resources to enhance the Stroke Trials Network; c) train the next generation of stroke clinical and translational researchers. The Florida RCC encompasses a large network of participating acute stroke, rehabilitation and pediatric hospitals that span across Florida, to ensure robust enrollment of an ethnically diverse population that reflects the changing demographics of the US. Our stroke program has a successful track record of participating in numerous NINDS acute and secondary prevention stroke trials, and is involved in other NIH networks and coordinates multicenter studies. Through our participating sites, extended referral network and multidisciplinary expertise, we will build upon the close partnership with pre-hospital Emergency Services, Emergency Medicine, Vascular Neurosurgery, Interventional Neurology, Neuro-Critical Care, Pediatric Neurology and Neurorehabilitation, as well as on academic-public- private institutional collaborations, to enroll and manage potential study participants. We also have unique resources that we can bring to the network. Integrated collaboration among cutting edge researchers in the areas of preclinical stroke, stem cells, human genomics, biorepository, brain bank, and the Miami CTSI make us uniquely positioned to develop, propose and implement novel translational early phase projects. The large residency and fellowship training programs in Neurosciences, the multidisciplinary educational resources in the institution, and our track record of mentoring clinical researchers, position our center to effectively train stroke researchers in clinical and translational research through a structured mentored program. Over the past funding cycle we have been an outstanding StrokeNet member: we expanded the RCC representation across Florida by adding new outstanding sites, recruited well into StrokeNet trials, were a top performer in regulatory metrics, trained 3 StrokeNet scholars, participated in 3 working groups and committees, submitted new proposals to the Network, and were engaged in all aspects of the program. Therefore, we have the depth and breadth of expertise and resources to successfully function as a RCC in the StrokeNet.