University of Michigan Regional Coordinating Center (RCC) StrokeNet

密歇根大学区域协调中心 (RCC) StrokeNet

• 批准号: 9756485
• 负责人: DEVIN L BROWN
• 金额: $ 31.04万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-15 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9756485
• 关键词: Accident and Emergency department; Adult; Agreement; Applied Research; Area; Basic Science; Blood Vessels; Cause of Death; Childhood stroke; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Design; Clinical Trials Network; Clinical Trials Support Unit; Collaborations; Conduct Clinical Trials; Data Quality; Development; Emergency Care; Emergency Medicine; Enrollment; Faculty; Fellowship Program; Foundations; Funding; Geography; Goals; Health; Home environment; Informed Consent; Infrastructure; Institutes; Lead; Leadership; Mentorship; Michigan; Mission; NCI Scholars Program; National Institute of Neurological Disorders and Stroke; Neurological emergencies; Neurology; Patients; Phase; Phase III Clinical Trials; Physician Executives; Population; Population Heterogeneity; Prevention; Public Health Schools; Recording of previous events; Records; Recovery; Rehabilitation therapy; Research; Research Personnel; Research Training; Resources; Site; Speed; Stroke; Stroke prevention; StrokeNet clinical trials; System; Training; Training Programs; United States National Institutes of Health; Universities; Wood material; care systems; career; career development; cohesion; design; disability; experience; innovation; investigator training; multidisciplinary; patient population; pediatric emergency; programs; protocol development; recruit; stroke clinical trials; stroke intervention; stroke patient; stroke trials; success; synergism; treatment trial

The purpose of a University of Michigan Regional Coordinating Stroke Center (UM RCC) is to continue to participate fully in the NIH StrokeNet clinical trials network through clinical trial development, enrollment, and implementation, and the training of early stage investigators in stroke research. The University of Michigan has a long track record of clinical science excellence, expertise in clinical stroke management, excellence in creating stroke systems of care, expertise in stroke clinical trial design and implementation, and a proven ability to recruit subjects. The UM RCC includes affiliate spokes in a geographically focused region with which UM has a history of collaboration, and provides access to a large and diverse stroke patient population. UM has tremendous infrastructure for the conduct of clinical trials including a CTSA-funded Michigan Institute for Clinical & Health Research, and Clinical Trial Support Units, both of which directly benefit the UM RCC. Moreover, the Departments of Emergency Medicine and Neurology at UM are fully supportive of the continuation of a UM RCC. The applicants are part of a dedicated multidisciplinary team of investigators who are experienced in stroke clinical trials and enthusiastic to continue working collaboratively on Network trials and offer enrollment to all eligible patients. Also included are world-class experts in stroke basic science who can continue to contribute to the leadership and training within a UM RCC and the overall network. The UM RCC has proposed and will continue to propose trials for conduct in the Network. One UM RCC proposed clinical trial has been approved for funding. The University of Michigan is already home to the NINDS-funded Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) National Clinical Coordinating Center (PI: Barsan) and its prior incarnation, the Neurological Emergencies Treatment Trials (NETT), and thus has tremendous experience with the design and conduct of clinical trials within networks. Equally as important to the successful conduct of clinical trials within a UM RCC, the UM Stroke Program has a proven track record for developing academic clinical researchers in stroke, as this is the primary mission of its fellowship program. Unique resources are available at UM for formal didactic training in clinical research through its nationally recognized School of Public Health and its Clinician Scholars Program. Trainees within a UM RCC also benefit tremendously from the mentorship of a highly integrated multidisciplinary faculty with significant expertise in stroke clinical trials and clinical stroke research. The initial years of the UM RCC have proven its success in clinical trial enrollment, early investigator training, multi-level network engagement, and clinical trial proposal development.

密歇根大学区域协调中风中心（UM RCC）的目的是继续 通过临床试验开发、入组，充分参与NIH StrokeNet临床试验网络， 实施和培训中风研究的早期研究者。密歇根大学 在临床科学方面的长期卓越记录，在临床卒中管理方面的专业知识， 创建中风护理系统，中风临床试验设计和实施方面的专业知识， 招募受试者的能力。UM RCC包括地理上集中的区域中的分支机构， UM有合作的历史，并提供了访问一个大的和多样化的中风患者群体。嗯 拥有进行临床试验的巨大基础设施，包括CTSA资助的密歇根研究所， 临床与健康研究和临床试验支持单位，这两个单位都直接使UM RCC受益。 此外，澳大的急诊科及神经科亦全力支持 继续一个UM RCC。申请人是一个专门的多学科调查小组的一部分， 在中风临床试验方面经验丰富，并热衷于继续在网络试验中合作 并为所有符合条件的患者提供登记。还包括世界级的中风基础科学专家， 可以继续为UM RCC和整个网络内的领导和培训做出贡献。的UM 区域合作理事会已经提议并将继续提议在该网络中进行试验。拟议一个UM RCC 临床试验已获资助。密歇根大学已经是NINDS资助的大学所在地 EmeRgENcy Care临床试验网络（SIREN）国家临床协调中心的创新策略 (PI：Barsan）及其前身，神经紧急情况治疗试验（NETT），因此， 在网络内设计和开展临床试验方面拥有丰富的经验。同样重要的是， 在UM RCC内成功进行临床试验，UM卒中计划在以下方面有着良好的记录： 发展中风的学术临床研究人员，因为这是其奖学金计划的主要使命。 独特的资源可在UM通过其全国性的临床研究的正式教学培训 公认的公共卫生学院及其临床医生学者计划。UM RCC内的受训人员也将受益 在中风临床试验和临床中风研究方面具有重要专业知识的高度综合的多学科教师的指导下，UM RCC的最初几年已经证明了它的成功， 临床试验招募、早期研究者培训、多层次网络参与和临床试验提案制定。