The Penn Postdoctoral Training Program in the Ethical, Legal and Social Implications of Genetics and Genomics

基因组技术的快速发展，如下一代测序，正在转变 我们对人类健康和人类历史的理解。这些技术还有望 前所未有的力量，可以干预有疾病或有疾病风险的个人的身体，以及 甚至改变尚未出生的个体的身份或未来。这样的知识和力量 隐含着巨大的责任，以促进核心道德价值观的方式使用它们，包括 个人和集体福利、社会正义、保护弱势群体和尊重两者 人的自治和社区的利益。履行这些责任 需要一支由多样化、训练有素的跨学科学者组成的干部队伍 以批判和尊重的态度应对遗传基因带来的深刻的伦理、法律和社会挑战 和基因组技术。响应这一需求，宾夕法尼亚大学的根本目标是 遗传学的伦理、法律和社会影响(ELSI)博士后培训计划 基因组学是为受训人员做好准备，使他们成为具有创造力的独立研究人员 ELSI研究领域。该计划设在医学伦理学和医学部 佩雷尔曼医学院的卫生政策将通过两个核心实现这一目标 组成部分：1)完成医学伦理学硕士学位(MSME)，将 概念生命伦理学、经验方法和遗传科学方面的培训，以及2)指导 原创性研究导致高影响力的经验性和概念性学术出版物。一个 杰出的项目教员，由12名经验丰富的ELSI学者和导师组成 佩雷尔曼医学院、艺术与科学学院和宾夕法尼亚大学的系 法学院将担任培训学员的导师。受训人员将在和 参与医德与卫生政策部每月进行的工作 和系列研讨会，参加大学范围内的各种研讨会和会议 重点关注遗传医学和科学以及伦理、法律、经济和卫生 政策，并在国家会议上发言。学员还将接触到基因药物 通过跟踪来自所有成年人的专家遗传学家和顾问， 儿科和生殖遗传学实践。最后，受训人员将成为以下组织的成员之一 宾夕法尼亚大学机构审查委员会(IRBs)审查与ELSI相关的研究。该计划 将培训七名博士后学者，每人参加三年，并将 通过广泛的有针对性的培训确保注册学员的学科和背景的多样性 与不同的学术团体进行接触。

Rapid advances in genomic technologies such as next-generation sequencing are transforming our understandings of both human health and human history. These technologies also promise unprecedented power to intervene on the bodies of individuals with or at risk of disease, and even to alter the identities or futures of individuals not yet born. Such knowledge and power imply immense responsibility to use them in ways that promote core ethical values, including individual and collective welfare, social justice, protection of the vulnerable, and respect for both the autonomy of persons and the interests of communities. Fulfilling these responsibilities requires a cadre of diverse, highly trained, interdisciplinary scholars prepared to engage critically and respectfully with the profound ethical, legal and social challenges raised by genetic and genomic technologies. Responding to this need, the fundamental goal of the Penn Postdoctoral Training Program in the Ethical, Legal and Social Implications (ELSI) of Genetics and Genomics is to prepare trainees for success as creative, independent investigators in the field of ELSI research. The program, housed within the Department of Medical Ethics and Health Policy at the Perelman School of Medicine, will achieve this goal through two core components: 1) completion of a Master of Science in Medical Ethics (MSME) degree that blends training in conceptual bioethics, empirical methods and genetic science, and 2) mentored original research leading to high-impact empirical and conceptual scholarly publications. An outstanding program faculty, consisting of 12 experienced ELSI scholars and mentors from departments at the Perelman School of Medicine, the School of Arts and Sciences and the Penn Law School, will serve as preceptors to program trainees. Trainees will present at and participate in the Department of Medical Ethics and Health Policy's monthly works-in-progress and seminar series, attend a wide range of seminars and conferences across the University focused on genetic medicine and science as well as on ethics, law, economics and health policy, and present at national meetings. Trainees will also gain exposure to genetic medicine through shadowing expert geneticists and counselors drawn from the full spectrum of adult, pediatric and reproductive genetics practice. Finally, trainees will serve as members of one of the UPenn institutional review boards (IRBs) that review ELSI-related research. The program will train seven postdoctoral scholars, each of whom will participate for three years, and will ensure diversity of discipline and background among enrolled trainees by extensive targeted outreach to diverse academic communities.