2019 Modulation of Neural Circuits and Behavior Gordon Research Conference and Gordon Research Seminar

2019神经回路与行为调节戈登研究会议暨戈登研究研讨会

• 批准号: 9760082
• 负责人: LISA STOWERS
• 金额: $ 0.6万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-01 至 2020-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9760082
• 关键词: Address; Amaze; Anatomy; Animal Model; Animals; Attention; Basic Science; Behavior; Behavioral; Biological; Biotechnology; Brain; Brain Diseases; Brain region; Cellular biology; Clinic; Cognitive; Communication; Communities; Complex; Computational Biology; Computer Analysis; Creativeness; Data Set; Devices; Discipline; Disease; Electrophysiology (science); Elements; Ensure; Environment; Fostering; Future; Generations; Genetic; Genomics; Goals; Health; Image; Impaired cognition; Individual; Instinct; Institutes; Intelligence; International; Journals; Knowledge; Learning; Mental Depression; Mentors; Methods; Mission; Molecular Biology; Molecular Target; Motivation; National Institute of Child Health and Human Development; National Institute of Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute on Deafness and Other Communication Disorders; Nervous system structure; Neurohormones; Neuromodulator; Neurons; Neurosciences; Participant; Pharmaceutical Preparations; Post-Traumatic Stress Disorders; Postdoctoral Fellow; Process; Proteomics; Publishing; Request for Proposals; Research; Research Personnel; Schizophrenia; Science; Scientist; Senior Scientist; Sister; Sleep; Switzerland; Symptoms; Synapses; System; Therapeutic; Time; Translating; Translational Research; addiction; brain dysfunction; cell type; cognitive function; environmental change; feeding; flexibility; graduate student; information processing; insight; interest; learned behavior; meetings; member; mental state; neural circuit; neuropsychiatry; neuroregulation; next generation; programs; receptor; relating to nervous system; response; sex; symposium; tool; translational scientist; unpublished works

PROJECT SUMMARY: This proposal requests R13 support for the third meeting of the Gordon Research Conference (GRC) with an associated Gordon Research Seminar (GRS) for young scientists on “Modulation of Neural Circuits and Behavior” from May 26-31, 2019, in Les Diablerets, Switzerland. Brains adjust information processing and optimize behaviors in response to ever-changing environmental demands. This astonishing flexibility relies on the modulation of brain functions at multiple levels, from synapses to neural circuits. The modulation of brain functions regulates basic biological states such as feeding, sleep or sex, and it is of key importance for cognitive brain functions such as attention and learning. Deep insights into neuromodulation are not only critical to understand the neural basis of intelligence and behavior but also to understand how different mental states, motivation, attention and other important phenomena are controlled. Moreover, mechanistic insights into neuromodulatory mechanisms are key to understand brain dysfunctions and diseases including depression, post-traumatic stress disorder, and many others. This conference will bring together scientists with diverse backgrounds to discuss current concepts and exciting new results in this broad field. The meeting will cut across disciplines and focus on topics that have a high potential to synergize. Rather than following traditional subdivisions of the broad field of neuromodulation, the session topics bridge between scientific communities and disciplines. We expect that the organized and informal discussions will generate new insights and highlight promising directions of future progress. This meeting is unique, since it brings together scientists from disparate fields to foster collaborative ideas and activities in the synthesis of the common principles of neuromodulation. This will be facilitated by specific sections of the program devoted to general discussions that will cover the presentations that address the common themes of each day. As a result of amazing advances in genomics and proteomics, computational analysis of complex datasets, new imaging and electrophysiology methods, and the ability to manipulate neural activity during innate and learned behavior, neuroscientists are now able to probe neuromodulation in identified neurons, circuits, and intact animals. The GRC/GRS on Neuromodulation will promote discussion of new research and strengthen communication between bench scientists, theorists, and tool developers. Finally, this meeting will feature participants of different generations, with representation of early pioneering investigators, current leaders, and junior investigators providing an exceptional opportunity for intimate exchanges of knowledge and ideas. Together these should drive promising future directions in the study of neuromodulation, which are in line with the mission of NINDS and its sister institutes, NIDA, NICHD, NIA and NIDCD.

项目概要： 该提案要求R13支持戈登研究会议（GRC）第三次会议， 相关的戈登研究研讨会（GRS）的年轻科学家对“调制的神经回路和 行为”，2019年5月26日至31日，在瑞士的Les Diablerets。大脑调整信息处理， 优化行为以应对不断变化的环境需求。这种惊人的灵活性依赖于 从突触到神经回路的多层次脑功能调节。脑的调制 功能调节基本的生物状态，如进食，睡眠或性，它是至关重要的， 认知大脑功能，如注意力和学习。对神经调节的深入了解不仅 这对于理解智力和行为的神经基础至关重要， 状态、动机、注意力和其他重要现象都受到控制。此外，机械的见解 了解神经调节机制是了解大脑功能障碍和疾病的关键，包括 抑郁症，创伤后应激障碍，以及许多其他疾病。这次会议将汇集科学家 与不同的背景，讨论当前的概念和令人兴奋的新成果，在这个广泛的领域。会议 将跨越学科，重点关注具有高度协同潜力的主题。而不是遵循 神经调节的广泛领域的传统细分，会议主题科学之间的桥梁 社区和纪律。我们期望，有组织的非正式讨论将产生新的成果， 深入的见解和突出未来进展的有希望的方向。 这次会议是独一无二的，因为它汇集了来自不同领域的科学家，以促进合作的想法， 在神经调节的共同原则的合成活动。这将有助于具体的 该计划的部分专门用于一般性讨论，将涵盖解决 每天的共同主题。由于基因组学和蛋白质组学的惊人进步， 复杂数据集的分析，新的成像和电生理学方法，以及操纵神经元的能力。 活动在先天和后天行为，神经科学家现在能够探测神经调制在确定的 神经元、电路和完整的动物。关于神经调节的GRC/GRS将促进对新的 研究并加强实验室科学家、理论家和工具开发人员之间的沟通。最后 会议将以不同世代的参与者为特色，代表早期开拓性的研究人员， 现任领导人和初级调查人员提供了一个特殊的机会， 知识和思想。总之，这些应该推动有希望的未来方向的研究 神经调节，这是符合使命的NINDS及其姐妹机构，NIDA，NICHD，NIA和 NIDCD。