Cortisol Synchrony in Adolescents and Their Parents

青少年及其父母的皮质醇同步性

• 批准号: 9889157
• 负责人: Daphne C. Hernandez
• 金额: $ 7.88万
• 依托单位: UNIVERSITY OF HOUSTON
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-07 至 2023-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9889157
• 关键词: Acute; Adolescent; Adult; Age; Alcohol or Other Drugs use; Anxiety; Applications Grants; Area; Biological Assay; Child; Chronic; Chronic stress; Climate; Communities; Country; Development; Disclosure; Documentation; Economics; Enrollment; Environment; Exposure to; Face; Family; Fright; Future; Goals; Health; Household; Human; Hydrocortisone; Immigrant; Individual; Interdisciplinary Study; Latino; Legal; Light; Measures; Mental Depression; Mental Health; Methodology; Mexican; Modeling; Outcome; Parents; Participant; Pathway interactions; Patient Self-Report; Pattern; Physiological; Policies; Population; Populations at Risk; Poverty; Prevention program; Production; Proxy; Recording of previous events; Reporting; Research; Research Personnel; Research Project Grants; Risk; Saliva; Sampling; Standardization; Stress; Structure; Surveys; United States Substance Abuse and Mental Health Services Administration; Vulnerable Populations; Youth; base; behavioral health; biobehavior; community based participatory research; cost; experience; health disparity; innovation; insight; intervention program; member; psychosocial; stressor

PROJECT SUMMARY/ABSTRACT Despite their citizenship, over 3.2 million US-born Latino children of undocumented parents (i.e., those in “mixed-status families”) experience chronic stress associated with potential or actual forced deportation of their parents. Relative to US-born Latino children in documented-status families, US-born Latino children in mixed- status families are exposed to additional acute and chronic stressors placing them at elevated risk for substance use, anxiety and depression. The absence of research using direct assessment of family documentation status impedes the ability to determine structural burden of stress exposure and its health consequences. Further, chronic stress, such as the burden of deportation stress within immigrant families, can be culturally bound and standardized survey measures may not be indicative of the negative health impact that physiological stress has within the family environment. The objective of this study is to determine the potential mental and behavioral health vulnerabilities of US-born Latino adolescents (ages 12- 16) with undocumented parents. This will be done through a dyadic bio-behavioral project based on central principles of community– based research. The primary aim is to describe cortisol synchrony in Latino adolescent-parent dyads, and compare the synchrony profiles of dyads in mixed-status families with those in documented families. Aim 2 is to delineate variability in self-appraised stressors among mixed-status and documented-status US-born Latino adolescent-immigrant parent dyads. Aim 3 will describe the magnitude of correlations of cortisol synchrony with parent and adolescent self-appraised stressors and youth self-reports of substance use, anxiety, and depression. This study will enroll n=25 US-born Mexican adolescent-immigrant parent dyads from mixed-status families and n=25 US-born Mexican adolescent-immigrant parent dyads from documented-status families who reside in the Houston-area. Direct assessments and self-reported surveys will be utilized. Saliva samples will be assayed for cortisol. Adolescents and parents will report on deportation stress, acculturative stress (SAFE- R), and economic stress (HSI-A and HSI-2 subscales). Adolescents will also report on substance use, anxiety (PAI), and depression (CES-D). This study is highly innovative for three reasons: (1) Explicit focus on a dominant contemporary issue – the management of US-born children and their undocumented immigrant parents – advanced under the previous administration but currently being called into question; (2) While there is a long history of studies focused on individuals' diurnal pattern of cortisol, there is a dearth of research using a dyadic bio-behavioral approach to capture cortisol synchrony among adolescent-immigrant parent households; and (3) A refinement in methodologies by using complementary objective and subjective assessments of stress to avoid potential ambiguity in health effects, recognizing that deportation stress is culturally bound. This study has implications to inform future community-based research projects focused on US-born children of undocumented immigrant parents, one of the fastest growing segments of the US.

项目总结/摘要 尽管他们的公民身份，超过320万美国出生的拉丁裔儿童的无证父母（即，中的那些 “混合身份的家庭”）经历与潜在或实际强迫驱逐其子女有关的长期压力。 父母相对于美国出生的拉丁裔儿童在文件的地位家庭，美国出生的拉丁裔儿童在混合- 地位家庭暴露于额外的急性和慢性压力源，使他们面临更高的风险， 物质使用、焦虑和抑郁。缺乏直接评估家庭的研究 文件状态阻碍了确定压力暴露及其健康的结构性负担的能力 后果此外，长期的压力，如移民家庭中的驱逐压力负担， 受文化约束和标准化的调查措施可能并不表明负面的健康影响， 家庭环境中的生理压力。这项研究的目的是确定潜在的 美国出生的拉丁裔青少年（12- 16岁）的精神和行为健康脆弱性， 父母这将通过一个基于社区中心原则的二元生物行为项目来完成- 基于研究。主要目的是描述拉丁美洲人的皮质醇同步性， 比较混合身份家庭与有文献记载家庭中二对子女的同步性。目标二是 描述在美国出生的拉丁裔中，混合身份和有文件身份的拉丁裔自我评价压力源的变化 移民-移民父母二人组。目标3将描述皮质醇同步性与 父母和青少年自我评估的压力源和青少年自我报告的物质使用，焦虑， 萧条本研究将入组n=25名美国出生的墨西哥裔移民父母二人组， 家庭和n=25个美国出生的墨西哥裔移民父母二人组，他们来自有文件证明的家庭， 住在休斯顿地区。将利用直接评估和自我报告的调查。唾液样本将 检测皮质醇。青少年和家长将报告驱逐出境的压力，文化适应压力（安全- R）和经济压力（HSI-A和HSI-2分量表）。青少年还将报告物质使用，焦虑 (PAI)抑郁症（CES-D）。本研究具有很强的创新性，原因有三：（1）明确关注 当代的一个主要问题--对在美国出生的儿童及其非法移民的管理 父母-前政府提出，但目前受到质疑;（2）虽然有 关于个体皮质醇昼夜模式的研究历史悠久，但缺乏使用 一种双元生物行为方法来捕获移民父母中皮质醇的同步性 家庭;（3）通过使用互补的客观和主观方法来改进方法 评估压力，以避免对健康影响的潜在模糊性，认识到驱逐出境的压力， 文化束缚。这项研究对未来以社区为基础的研究项目具有启示作用， 无证移民父母在美国出生的孩子，是美国增长最快的群体之一。