Bio-Behavioral and Community Science Core

项目总结/摘要 生物行为和社区科学核心（核心J） 我们建议继续生物行为和社区科学核心，以前称为行为和 社会科学核心，为哈佛大学艾滋病研究中心（HU CFAR）。自2014年以来，这一核心 为CFAR成员提供咨询和其他支持，以设计研究报告， 采用最先进的方法，制定干预措施，限制艾滋病毒传播，提高血清状况 意识，参与护理和药物依从性，同时解决社会和 阻碍实现这些目标的结构性因素。该核心的工作已产生4 HU CFAR 发展奖和25个NIH K-或R-系列奖，以早期职业研究者和多个跨 在当前供资期间的CFAR合作。核心小组还领导了若干举措，包括 建立了与埃默里CFAR共同领导的CFAR间预防抗逆转录病毒工作组， 并积极参与trans-CFAR行为和社会科学研究网络。这个核心有 也越来越注重社区参与，核心领导层致力于参与 受影响社区参与研究进程，并让所有关键利益攸关方参与， 整合生物行为，社会和社区为基础的研究，在艾滋病毒的治疗，预防，治愈， 疫苗研发。最后，本核心对协商的需求增加表明， 有兴趣整合这项研究。因此，我们提出了一个生物行为和社区科学的核心， 以下目标：1）为HU CFAR成员提供行为方面的合作和咨询服务， 艾滋病毒预防、治疗和转化研究的社会、结构和社区科学方面; 2） 利用HU CFAR临床研究的基础设施，促进新的综合行为/社会和 社区科学研究; 3）通过社区，促进可持续的学术-社区伙伴关系 从事研究，包括指导初级研究人员，教育和研究传播。 具体而言，核心小组将提供赠款建议方面的援助; 研究，干预发展，定量评估发展，混合方法研究， 社区参与式研究。核心将继续通过促进 通过在早期干预中整合行为/社会科学，使生物医学试验取得成功 设计;通过催化结合行为/社会和生物医学研究的想法;并通过促进强有力的 学术界与社区的伙伴关系，并获得社区的支持，以减少不信任， 新技术进入社区。

PROJECT SUMMARY/ABSTRACT Bio-Behavioral and Community Science Core (Core J) We propose to continue the Bio-behavioral and Community Science Core, formerly called the Behavioral and Social Sciences Core, for the Harvard University Center for AIDS Research (HU CFAR). Since 2014, this Core has provided consultations and other support to CFAR members for the design of research studies that utilize state-of-the-art methodologies to develop interventions to limit HIV transmission, and increase serostatus awareness, engagement in care, and medication adherence, while simultaneously addressing the social and structural factors that impede achieving these goals. The work of this Core has resulted in 4 HU CFAR Developmental awards and 25 NIH K- or R-series awards to Early Career Investigators and multiple inter- CFAR collaborations during the current funding period. The Core has also led several initiatives, including the establishment of the inter-CFAR Antiretrovirals for Prevention Working Group, co-led with the Emory CFAR, and active engagement in the trans-CFAR Behavioral and Social Science Research Network. This Core has also been increasingly focused on community engagement, and the Core leadership is dedicated to engaging affected communities in the research process and to engaging all key stakeholders about the need for integration of bio-behavioral, social, and community-based research in HIV treatment, prevention, cure, and vaccine development. Finally, the increased demand for consultations by this Core indicates a greater interested in integrating this research. Thus, we propose a Bio-behavioral and Community Science Core with the following goals: 1) To provide collaborative and consultation services to HU CFAR members on behavioral, social, structural, and community science aspects of HIV prevention, treatment, and translational research; 2) To leverage infrastructure from HU CFAR clinical research to facilitate new integrative behavioral/social and community science studies; 3) To foster sustainable academic-community partnerships through community engaged research including mentorship of junior investigators, education, and research dissemination. Specifically, the Core will offer assistance with grant proposals; consultations on methods for qualitative research, intervention development, quantitative assessment development, mixed-method research, and community-based participatory research. The Core will continue to add value to the HU CFAR by facilitating the success of biomedical trials through the integration of behavioral/social sciences early in intervention design; by catalyzing ideas for combined behavioral/social and biomedical research; and by facilitating strong academic-community partnerships and obtaining community buy-in, to reduce mistrust and to the hasten the reach of new technologies into communities.