The 5th Stevens Conference on Bacteria-Material Interactions

第五届史蒂文斯细菌-材料相互作用会议

• 批准号: 9763260
• 负责人: Matthew Libera
• 金额: $ 1万
• 依托单位: STEVENS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-06-01 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9763260
• 关键词: Address; Antibiotic Resistance; Area; Bacteria; Biocompatible Materials; Chronic; Clinical; Communities; Country; Development; Devices; Discipline; Doctor of Philosophy; Engineering; Failure; Financial Support; Future; Grant; Healthcare Systems; Human; In Vitro; Industrialization; Infection; Infrastructure; Methods; Microbial Biofilms; Nationalities; Patients; Performance; Personal Satisfaction; Postdoctoral Fellow; Research; Research Support; Science; Scientist; Students; Surface; Tissues; Travel; age group; career; career development; design; doctoral student; hip replacement arthroplasty; implantable device; in vivo evaluation; knee replacement arthroplasty; pressure; research and development; symposium

Project Summary This grant provides financial support for the 5th Stevens Conference on Bacteria-Material Interactions being held in June of 2019. The interaction of bacteria with synthetic materials is an important emerging research area, because biomaterials-associated infection (BAI) has become a leading failure mechanism associated with tissue-contacting biomedical devices. Common examples are hip and knee replacements, but all devices are susceptible to infection. BAI occurs when bacteria colonize a biomaterial surface, develop into antibiotic-resistant surface-attached biofilms, and chronically infect the surrounding tissue. Most often, these infections can be resolved only by removing the implanted device, resolving the infection, and reinstalling a second device, all of which can have very significant both on patient wellbeing and on rapidly escalating expenses within the healthcare systems. This Conference brings together a cross-disciplinary group of academicians, clinicians, industrial scientists and engineers, and regulators from around the country and world to present and discuss the most recent research findings associated with the design, development, and use of infection-resisting biomaterials. As a result, the most important problems for future study are identified and can be addressed in the most impactful manner. The Conference also addresses one of the central and very practical issues of how to develop appropriate in vitro and in vivo tests that can be used to quantify and validate performance. Specifically, this grant partially supports the travel expenses associated with PhD research students, post-doctoral students, and early-career professionals who are establishing their careers in areas associated with biofilm research and infection- resisting biomaterials. Participation in the Conference by all of these younger scientists will provide them with important opportunities for networking and scientific exchange across nationalities, disciplines, and professional age groups that will enhance their career development as well as strengthen the overall human infrastructure within this rapidly growing and clinically impactful field of research and development.

项目摘要 该赠款为第五届史蒂文斯细菌材料会议提供财政支持 互动将于2019年6月举行。细菌与合成材料的相互作用是 一个重要的新兴研究领域，因为生物材料相关感染（BAI） 成为与组织接触生物医学装置相关的主要失效机制。 常见的例子是髋关节和膝关节置换，但所有设备都容易感染。 当细菌在生物材料表面定居，发展成耐药性时， 表面附着的生物膜，并慢性感染周围组织。通常，这些 感染只能通过取出植入器械、解决感染以及 重新安装第二个设备，所有这些都可能对患者的健康和 在医疗系统内迅速上升的费用。这次会议汇集 一个由院士、临床医生、工业科学家和工程师组成的跨学科小组， 来自全国和世界各地的监管机构介绍和讨论最新研究 与抗感染生物材料的设计、开发和使用相关的发现。 因此，未来研究的最重要的问题被确定，并可以在 最有影响力的方式。会议还讨论了一个核心和非常重要的问题， 如何开发适当的体外和体内试验的实际问题， 量化和验证性能。具体而言，这笔赠款部分支持差旅费 与博士研究生，博士后学生和早期职业专业人员有关 他们在生物膜研究和感染相关领域建立了自己的职业生涯， 抵抗生物材料。所有这些年轻科学家参加会议， 为他们提供了重要的机会，以建立网络和科学交流， 国籍、学科和专业年龄组，这将提高他们的职业生涯 发展，并在这一快速增长的社会中加强整体人力基础设施。 和临床上有影响力的研发领域。