Malaria immunity and vaccines

疟疾免疫和疫苗

• 批准号: nhmrc : 1077636
• 负责人: Prof James Beeson
• 金额: $ 52.04万
• 依托单位: Macfarlane Burnet Institute for Medical Research and Public Health
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/malaria-immunity-vaccines/518524
• 关键词: Malaria; immunity; vaccines

The major objective of this research is to advance the development of highly effective malaria vaccines through i) defining mechanisms and targets of human immunity to malaria to establish a rational basis for vaccine design; ii) advancing the development of lead candidates and promising new candidates and combinations; iii) advancing vaccine platforms that induce potent protective immune responses; iv) develop and validate urgently-needed immunological assays for vaccine development and testing

这项研究的主要目标是通过以下方式推动高效疟疾疫苗的开发：i)确定人类对疟疾的免疫机制和目标，为疫苗设计建立合理的基础；ii)推进主要候选和有前景的新候选和组合的开发；iii)推进可诱导有效保护性免疫反应的疫苗平台；iv)开发和验证疫苗开发和测试急需的免疫学分析方法。