Mbarara University Research Training Initiative (MURTI)

 描述(由申请者提供)：我们在姆巴拉拉科技大学(MUST)提出了姆巴拉拉大学培训倡议(MURTI)，以建设乌干达初级教员的能力，以开展专注于乌干达农村地区医疗保健差距的医学研究。撒哈拉以南非洲90%以上的人口生活在农村地区，由于获得卫生保健的机会有限，再加上教育有限和赤贫，农村地区的健康差距最大。由于其位于乌干达西南部的农村地区，与大多数位于城市中心的SSA研究机构相比，MUM处于独特的地位，可以促进改善SSA农村地区健康所需的科学研究。曼彻斯特大学是一所公立大学，成立于1989年，每年的研究经费超过300万美元，在研究生产率和发展中的初级教员队伍方面都呈现出指数级的增长。在过去的5年里，必须 科学生产力已经从每年30篇增长到80篇，每年产生300到1200次引用。基于这一增长，MUM目前在非洲大陆1306所大学中排名前5%。然而，这些科学生产力的大部分来自资深教员，培训下一代乌干达初级教员研究人员的迫切需求以及强大的潜力。穆尔蒂培训将涉及撒哈拉以南非洲具有重大公共卫生意义的三个科学领域：艾滋病毒/艾滋病、心血管疾病和精神健康障碍。这项培训计划还将培养研究管理和研究伦理方面的专门知识。拟议的穆尔蒂项目在重点建设农村地区的研究能力方面具有创新性。它将产生特别的影响，因为它将利用NIH、盖茨正在进行的每年150万美元的研究，以及与马萨诸塞州总医院(MGH)和哈佛公共卫生学院(HSPH)合作的慈善资助研究，为20名乌干达初级教员提供深入培训，他们将开展以公共部门调查为重点的农村卫生问题。为了实现我们的目标，我们提出了以下培训目标：(1)发展初级教员在艾滋病毒预防和治疗方面的研究专门知识，特别是在乌干达西南部农村；(2)建设乌干达初级教员的能力，以开发针对农村人口心血管疾病的新颖、循证的诊断和治疗策略；(3)为初级教员培养应对乌干达农村精神健康障碍的研究职业；以及(4)使初级教员具备必要的行政、研究伦理和研究沟通能力，以便成功地成为乌干达下一代独立调查人员。通过这些目标，穆尔蒂将建设必须初级教员进行尖端社会行为、生物医学和流行病学研究的能力。这四个目标将得到北美领先机构(MGH和HSPH)的技术专长的支持，这些机构与MIME和当地现有的专业知识建立了长达十年的合作关系。

 DESCRIPTION (provided by applicant): We propose the Mbarara University Training Initiative (MURTI) at the Mbarara University of Science and Technology (MUST) to build the capacity of Ugandan junior faculty to conduct medical research focusing on health care disparities in rural Uganda. Over 90% of the population in sub-Saharan Africa lives in rural settings where health disparities are greatest due to limited access to health care combined with limited education and extreme poverty. With its rural location in southwest Uganda, MUST is uniquely positioned to advance the science needed to improve health in rural SSA - in contrast to most SSA research institutions, which are located in urban centers. MUST is a public university founded in 1989 that, with more than $3 million in annual research funding, has shown exponential growth in both its research productivity and its pool of developing junior faculty. In the last 5 years, MUST scientific productivity has grown from 30 to 80 publications yearly, generating 300 to 1200 annual citations. Based on this growth, MUST is now ranked among the top 5% of the 1,306 universities on the African continent. However, most of this scientific productivity has come from senior faculty, and there is a pressing need - as well as strong potential - to train the next generation of Ugandan junior faculty researchers. MURTI training will address three scientific areas of great public health significance in sub- Saharan Africa: HIV/AIDS, cardiovascular diseases, and mental health disorders. This training initiative will also build expertise in researh administration and research ethics. The proposed MURTI is innovative in its focus on building research capacity in rural settings. It will have particular impact because it will leverage $1.5M/year in ongoing NIH, Gates, and philanthropically funded research in partnership with Massachusetts General Hospital (MGH) and the Harvard School of Public Health (HSPH) to provide in-depth training to 20 Ugandan junior faculty who will conduct public sector investigation focused rural health issues. To reach our goal, we propose the following training aims: (1) To develop junior faculty research expertise in HIV prevention and treatment, particularly in rural southwestern Uganda; (2) To build the capacity of Ugandan junior faculty to develop novel, evidence-based diagnostic and treatment strategies for cardiovascular diseases in rural populations; (3) To prepare junior faculty for research careers addressing mental health disorders in rural Uganda; and (4) To equip junior faculty with the administrative, research ethics, and research communications capacities necessary to succeed as the next generation of independent investigators in Uganda. Through these aims, the MURTI will build the capacity of MUST junior faculty to conduct cutting edge social-behavioral, biomedical, and epidemiologic research. These four aims will be supported by technical expertise from leading North American institutions (MGH and the HSPH) that have developed decade-long collaborations with MUST and locally available expertise.