Functional Genomics and Bioinformatics Core
功能基因组学和生物信息学核心
基本信息
- 批准号:9767220
- 负责人:
- 金额:$ 27.17万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:
- 资助国家:美国
- 起止时间:至
- 项目状态:未结题
- 来源:
- 关键词:AddressApplications GrantsBindingBioinformaticsBiologicalBiological AssayCellsCenters of Research ExcellenceChildhoodChromatinClustered Regularly Interspaced Short Palindromic RepeatsComplexCore FacilityCustomDNADNA Sequencing FacilityDNA-Protein InteractionData AnalysesData SetDevelopmentDiseaseEnvironmentEpigenetic ProcessEquipmentEukaryotic CellExperimental DesignsFee-for-Service PlansFundingGene ExpressionGene Expression ProfilingGenesGeneticGenetic VariationGenomeGenome engineeringGenomic SegmentGenomicsGoalsGoldGuide RNAHigh-Throughput Nucleotide SequencingHuman ResourcesIn Situ HybridizationIndividualInfrastructureInstitutesInvestigationInvestigator-Initiated ResearchLaboratoriesManuscriptsMediatingMedicalMethodsMolecularMolecular BiologyNucleic AcidsPatternPediatric ResearchPerformancePhasePhysiciansPreparationPrincipal InvestigatorProtocols documentationPublicationsRNAResearchResearch PersonnelResearch SupportResourcesSamplingScientistServicesSignal TransductionSouth DakotaStructureSystemTechniquesTechnologyTimeTissuesTrainingTranscriptUnited States National Institutes of HealthWorkcell typechromatin immunoprecipitationdata managementdesignepigenetic variationepigenomeexperimental studyflexibilityfunctional genomicsgenome editinghigh throughput screeninghistone modificationmicrobialnovel strategiesnucleaseoperationpreclinical studyprogramstranscription factortranscriptometranscriptome sequencing
项目摘要
PROJECT SUMMARY
The Functional Genomics and Bioinformatics Core facility in the Center for Pediatric Research offers efficient,
high quality and flexible services in molecular and genomics assays for COBRE Project Leads and other
researchers in Sanford Research and regional institutes. The establishment and operation of the Core provides
a centralized resource for infrastructure, expertise, equipment and technical capabilities to perform molecular
and functional genomics studies proposed by COBRE Project Leads. The Functional Genomics and
Bioinformatics Core facility provides personalized services for investigators from experimental design to assay
execution and data analysis. The state-of-the-art, high-throughput equipment in the laboratory enables a wide
range of molecular and genomics assays, including nucleic acid isolation and quality analysis and
manipulation, quantitative real-time PCR analysis, RNA in situ hybridization, chromatin immunoprecipitation
studies, bioinformatics services, and to facilitate CRISPR/Cas9 mediated genome editing and. In addition, the
Core facilitates high-throughput sequencing and bioinformatics studies. These services provided by the Core
have contributed extensively to publications, grant applications, and preclinical studies by Project Leads. A
plan is developed for a sustainable Core facility beyond COBRE funding period to meet the research demands
of our scientists. By providing the support, resources and expert Core services, the Functional Genomics and
Bioinformatics Core will enhance the overall institutional research capacity and promote the advancement of
this core group of scientists and physicians to build a stronger pediatric research program, and ultimately
increase the number of NIH-funded biomedical researchers in South Dakota.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Haotian Zhao其他文献
Haotian Zhao的其他文献
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{{ truncateString('Haotian Zhao', 18)}}的其他基金
(PQ1) Molecular circuit of multi-ciliogenesis regulates choroid plexus differentiation and tumor development
(PQ1)多纤毛发生的分子回路调节脉络丛分化和肿瘤发展
- 批准号:
10228589 - 财政年份:2017
- 资助金额:
$ 27.17万 - 项目类别:
(PQ1) Molecular circuit of multi-ciliogenesis regulates choroid plexus differentiation and tumor development
(PQ1)多纤毛发生的分子回路调节脉络丛分化和肿瘤发展
- 批准号:
9754793 - 财政年份:2017
- 资助金额:
$ 27.17万 - 项目类别:
(PQ1) Molecular circuit of multi-ciliogenesis regulates choroid plexus differentiation and tumor development
(PQ1)多纤毛发生的分子回路调节脉络丛分化和肿瘤发展
- 批准号:
9617572 - 财政年份:2017
- 资助金额:
$ 27.17万 - 项目类别: