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Molecular Genetics

分子遗传学

基本信息

批准号：
9335895
负责人：
Haotian Zhao
金额：
$ 14.21万
依托单位：
SANFORD RESEARCH/USD
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/9335895
关键词：
Address Affect Animals Biological Biological Assay Biomedical Research Capital Cells Centers of Research Excellence Child health care Childhood Core Facility Cultured Cells Custom DNA DNA Sequence Data Analyses Development Developmental Process Disease Environment Epigenetic Process Equipment Experimental Designs Fees Fostering Funding Gene Expression Gene Expression Profiling Gene Proteins Genes Genetic Genetic Services Genetic Variation Genome Genomic DNA Goals Growth Health Human Resources Individual Laboratories Manuscripts Medical Research Methods Mission Modification Molecular Molecular Biology Molecular Genetics Nature Nucleic Acids Pattern Pediatric Research Performance Physiological Preparation Protocols documentation RNA Reporter Genes Research Research Infrastructure Research Institute Research Personnel Resources Sampling Scientist Services South Dakota Techniques Technology Tissues Training Training Programs Transcript cell type data management design flexibility functional genomics gene function gene interaction genetic analysis multidisciplinary novel strategies programs translational study

项目摘要

PROJECT SUMMARY (See instructions): The major goal of this COBRE application is to foster the development of COBRE investigators in the Center of Pediatric Research and help them to succeed in their research programs. This will be carried out by a multidisciplinary group of researchers at Sanford Research/USD who are dedicated to basic and translational biomedical research. To promote the growth of the only multidisciplinary training program for pediatric basic and translational studies in South Dakota, the Sanford Research/USD will establish infrastructures to provide essential and centralized laboratory service to COBRE project leaders. The Molecular Genetics Core facility is a laboratory in the Children's Health Research Center offering efficient, high quality and affordable molecular genetics services for COBRE project leaders and other researchers in Sanford Research/USD. The state-of-the-art, high-throughput equipment in the laboratory will enable a wide range of molecular genetics assays, including extraction of nucleic acids from tissues and cells, quantitative and qualitative analysis of nucleic acid samples, gene expression analysis and training. The Molecular Genetics Core facility will provide personalized services for COBRE project leaders from experimental design to assay execution and data analysis. A plan is developed for a sustainable Molecular Genetics Core facility to serve the needs of COBRE project leaders and other researchers in Sanford Research/USD. By providing the funding, resources and core lab services, Sanford Research/USD will promote the advancement of this core group of scientists to build a stronger pediatric research program, and ultimately increase the number of NlH-funded biomedical researchers in South Dakota.

项目总结（见说明）：该COBRE应用程序的主要目标是促进儿科研究中心的COBRE研究人员的发展，并帮助他们在研究项目中取得成功。这将由桑福德研究/USD的多学科研究人员小组进行，他们致力于基础和转化生物医学研究。为了促进南达科他州儿科基础和转化研究的唯一多学科培训计划的发展，桑福德研究中心/USD将建立基础设施，为COBRE项目负责人提供必要的集中实验室服务。分子遗传学核心设施是儿童健康研究中心的一个实验室，为COBRE项目负责人和Sanford Research/USD的其他研究人员提供高效，高质量和负担得起的分子遗传学服务。实验室中最先进的高通量设备将实现广泛的分子遗传学检测，包括从组织和细胞中提取核酸、核酸样本的定量和定性分析、基因表达分析和培训。分子遗传学核心设施将为COBRE项目负责人提供从实验设计到分析执行和数据分析的个性化服务。一个可持续发展的分子遗传学核心设施的计划，以满足COBRE项目领导人和其他研究人员在桑福德研究/USD的需求。通过提供资金，资源和核心实验室服务，桑福德研究/USD将促进这一核心科学家群体的进步，以建立一个更强大的儿科研究计划，并最终增加南达科他州的NIH资助的生物医学研究人员的数量。