权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Update and Novel Validation of the Pregnancy Physical Activity Questionnaire (PPAQ)

妊娠体力活动问卷 (PPAQ) 的更新和新颖验证

基本信息

批准号：
9766345
负责人：
LISA CHASAN-TABER
金额：
$ 22.77万
依托单位：
UNIVERSITY OF MASSACHUSETTS AMHERST
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-20 至 2021-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9766345
关键词：
Accelerometer Algorithms Behavior Calibration Categories Cellular Phone Classification Clip Data Detection Disease Dose Enrollment Etiology Exercise Fetal Diseases First Pregnancy Trimester Gestational Diabetes Goals Guidelines Hip region structure Household Image Intervention Studies Light Locomotion Measurement Measures Methods Monitor Non-Insulin-Dependent Diabetes Mellitus Occupational Outcome Participant Patient Self-Report Performance Persons Physical activity Physical assessment Population Postpartum Period Pre-Eclampsia Pregnancy Pregnancy Trimesters Pregnant Women Premature Birth Prevention Prospective cohort Public Health Questionnaires Research Risk Factors Sample Size Second Pregnancy Trimester Sports Standardization Strenuous Exercise Surveillance Methods System Tablets Text Text Messaging Third Pregnancy Trimester Time Transportation Update Validation Validity and Reliability Validity of Self Report Work Wrist actigraphy adverse pregnancy outcome caregiving cost design disorder prevention early pregnancy epidemiology study ethnic diversity exercise intervention fetal gestational weight gain high risk improved innovation instrument laboratory experiment lifestyle factors light intensity novel physical inactivity population based recruit sedentary sedentary lifestyle social media surveillance study therapy design tool tv watching

项目摘要

Project Summary Physical inactivity during pregnancy is an urgent public health concern and is implicated in excessive gestational weight gain, gestational diabetes, pre-eclampsia, and preterm birth. Self-reported assessments of physical activity (PA) continue to be the most common method for surveillance, epidemiological, and intervention studies of pregnancy PA given low compliance with activity monitor wear during pregnancy, need for large sample sizes, and the high cost of monitors. Therefore, it is critical that PA questionnaires be both valid and reliable. The Pregnancy Physical Activity Questionnaire (PPAQ) was developed by our group in 2004 (R03HD039341) as the first validated pregnancy PA questionnaire and has since become one of the most widely used instruments for assessing PA in this population. However, the PPAQ was validated using algorithms derived from accelerometers worn on the hip during fixed-duration simulated laboratory activities, which have been shown to perform poorly in free-living settings, particularly in the detection of sedentary and light intensity activity. Since that time, advances have been made in accelerometer and direct observation calibration and validation methods used to determine the validity of self-reported PA and sedentary behavior (SB). This is important as SB has recently emerged as an important new risk factor for adverse pregnancy outcomes independent of PA. Therefore, we are at a key point in time where innovative validation methods can be used to evaluate PPAQ performance in free-living settings and update and refine this widely used self-report tool. Our highly qualified research team will first update the PPAQ to include contemporary SB options (Aim #1). We will then recruit an ethnically diverse prospective cohort of 50 pregnant women in early pregnancy. In each trimester, participants will complete the updated PPAQ, then wear a wrist-worn Actigraph GT3XP-BTLE and a wearable camera over 7-d of free-living activity. Wearable camera images are the best objective method currently available to categorize the context of accelerometer- defined episodes of free-living activity. Using these data, we will: 1) Create a new short-form version of the PPAQ (PPAQ-SF) to reduce participant burden in studies which measure a wide range of other lifestyle factors (Aim #2); 2) Determine the accuracy and precision of the updated PPAQ and PPAQ-SF to estimate time spent in type (e.g., household/caregiving, occupational, sports/exercise, transportation, locomotion) and intensity classification (light, moderate, vigorous) of PA, and SB in a free-living setting (Aim #3). Thus, the updated PPAQ and new PPAQ-SF developed from this work will be the first questionnaires validated in free-living settings to provide accurate and precise estimates of PA and SB in pregnant women. These tools will be critical for: 1) surveillance studies assessing compliance with PA guidelines, 2) etiologic studies of PA and maternal-fetal outcomes designed to identify the optimal dose of pregnancy PA for the prevention of these disorders, and 3) to determine the efficacy of exercise interventions designed to increase PA in pregnancy.

项目概要怀孕期间缺乏身体活动是一个紧迫的公共卫生问题，并且与过度运动有关妊娠期体重增加、妊娠期糖尿病、先兆子痫和早产。自我报告的评估体力活动 (PA) 仍然是监测、流行病学和诊断的最常用方法鉴于怀孕期间佩戴活动监测仪的依从性较低，需要进行妊娠 PA 干预研究对于大样本量和监视器的高成本。因此，PA 问卷既要有效、可靠。妊娠体力活动问卷（PPAQ）是我们课题组于2004年开发的（R03HD039341）作为第一个经过验证的妊娠 PA 问卷，此后成为最有效的妊娠 PA 问卷之一广泛使用的工具来评估该人群的 PA。然而，PPAQ 已使用以下方法进行验证：在固定持续时间的模拟实验室活动期间，源自佩戴在臀部的加速度计的算法，已被证明在自由生活环境中表现不佳，特别是在检测久坐和光强度活动。从那时起，加速计和直接测量技术取得了进步。用于确定自我报告的 PA 有效性的观察校准和验证方法久坐行为（SB）。这一点很重要，因为 SB 最近已成为一个重要的新风险因素不良妊娠结局与 PA 无关。因此，我们正处于创新的关键时期。验证方法可用于评估自由生活环境中的 PPAQ 性能并更新和完善这个广泛使用的自我报告工具。我们高素质的研究团队将首先将 PPAQ 更新为包括当代 SB 选项（目标#1）。然后，我们将招募 50 名不同种族的前瞻性队列怀孕初期的孕妇。在每个三个月中，参与者将完成更新的 PPAQ，然后佩戴腕戴式 Actigraph GT3XP-BTLE 和可穿戴相机进行超过 7 天的自由生活活动。穿戴式相机图像是目前可用于对加速度计环境进行分类的最佳客观方法 - 自由生活活动的定义片段。使用这些数据，我们将： 1) 创建一个新的简短版本 PPAQ (PPAQ-SF) 可减轻测量各种其他生活方式因素的研究中参与者的负担（目标#2）； 2) 确定更新的 PPAQ 和 PPAQ-SF 的准确度和精密度以估计所花费的时间类型（例如家庭/看护、职业、运动/锻炼、交通、运动）和强度在自由生活环境中对 PA 和 SB 进行分类（轻度、中度、剧烈）（目标#3）。因此，更新后的根据这项工作开发的 PPAQ 和新的 PPAQ-SF 将是第一个在自由生活中验证的问卷设置以提供准确且精确的孕妇 PA 和 SB 估计。这些工具将对于以下方面至关重要：1) 评估 PA 指南遵守情况的监测研究，2) PA 的病因学研究和母婴结局旨在确定妊娠 PA 的最佳剂量，以预防这些情况疾病，以及 3) 确定旨在增加妊娠期 PA 的运动干预措施的功效。