Antimicrobial resistance in enteric bacteria from retail meat in Iowa: A NARMS Retail Food Surveillance Project

项目摘要/摘要 爱荷华州零售肉类的肠道细菌耐药性：一家NARMS零售商 2食品监测项目 3抗菌素耐药性(AMR)是影响人类福祉的主要健康威胁， 4个动物，以及全世界的环境。强大而全面的监控系统 5.强调“一个健康”的方法是有效对抗AMR的必要之举。在 6美国，国家抗菌素耐药性监测系统的零售部门 7(NARMS)隶属于食品和药物管理局，兽医中心(FDA- 8 CVM)对选定的肠道细菌(非伤寒沙门氏菌、 9来自零售生肉(鸡肉，磨碎的鸡肉)的弯曲杆菌、肠球菌和大肠杆菌) 14个州的10个火鸡、牛肉和猪排)。NARMS计划做出了重大贡献 11监测食物链中AMR的来源和趋势。加强对……的努力 12抗击AMR，FDA最近建立了一项合作协议计划，以扩大 13 NARMS遍布美国的监视网络。在此应用程序中，我们建议建立一个 14与NARMS合作，成为爱荷华州AMR监测的网络实验室。 15由于爱荷华州目前没有参加NARMS监测计划，它被列为 16新地点将大幅增加和加强该中心的能力和成效 17日，国家对零售食品进行监督。我们将获取和处理生肉样本。 18个(鸡肉、猪排、碎牛肉和碎火鸡)来自爱荷华州的杂货店和文化 19份用于沙门氏菌、弯曲杆菌、大肠杆菌和肠球菌的分离，并提供 每月向FDA提交20个分离物用于监测。我们的伙伴关系将有助于 21个NARM实现所述零售食品监督计划的目标和目的 22在FOA PAR-16-099“NARMS合作协议方案中加强和加强 23零售食品样本中的抗生素耐药性监测(U01)“。这项协作工作 24将大大有助于缓解食物链中的AMR，从而改善食品 25安全和公共卫生。 26 27 28

Project Summary/Abstract 1 Antimicrobial resistance in enteric bacteria from retail meat in Iowa: A NARMS Retail 2 Food Surveillance Project 3 Antimicrobial resistance (AMR) is a major health threat affecting the well-being of humans, 4 animals, and the environment worldwide. Robust and comprehensive surveillance systems 5 emphasizing the “One Health” approach are necessary for effectively combatting AMR. In the 6 United States, the retail arm of the National Antimicrobial Resistance Monitoring System 7 (NARMS) under the Food and Drug Administration, Center for Veterinary Medicine (FDA- 8 CVM ) performs surveillance of AMR in select enteric bacteria (non-typhoidal Salmonella, 9 Campylobacter, Enterococcus and Escherichia coli) from retail raw meat (chicken, ground 10 turkey and beef, and pork chop) in 14 states. The NARMS program has contributed significantly 11 to monitoring the sources and trends of AMR in the food chain. To enhance the effort on 12 combating AMR, FDA has recently established a cooperative agreement program to expand the 13 NARMS surveillance network throughout the U.S. In this application, we propose to establish a 14 partnership with the NARMS and become a network laboratory for AMR surveillance in Iowa. 15 Since Iowa does not currently participate in the NARMS surveillance program, its inclusion as a 16 new site would substantially increase and strengthen the capacity and effectiveness of the 17 national surveillance program in retail food. We will obtain and process raw meat samples 18 (chicken, pork chop, ground beef, and ground turkey) from grocery stores in Iowa and culture 19 them for isolation of Salmonella, Campylobacter, E. coli and Enterococcus, and provide the 20 isolates to the FDA for surveillance purpose on a monthly basis. Our partnership will help the 21 NARMs achieve the objectives and goals of the Retail Food Surveillance Program as described 22 in the FOA PAR-16-099 “NARMS Cooperative Agreement Program to Enhance and Strengthen 23 Antibiotic Resistance Surveillance in Retail Food Specimens (U01)”. This collaborative work 24 will significantly contribute to mitigation of AMR in the food chain and thus will improve food 25 safety and public health. 26 27 28