Non-Invasive Venous Waveform Analysis (NIVA) in patients with Heart Failure (HF)

容量超负荷（充血）发生在心力衰竭（HF）患者中，是主要原因 全世界老年人的住院率。不幸的是，临床体征和症状; 实验室值;现有的诊断工具在提供准确评估方面不可靠 卷的状态。使用独特的生理信号，无创静脉波形分析 （尼瓦），VolumeWatch已经开发了一种专有设备（“VasaWatch”）和算法， 用于监测HF患者的容量状态。人类和实验中的概念数据证明 动物模型，证明VasaWatch提供了可靠的血管内 卷状态。本快速通道SBIR中的研究将确定VasaWatch是一种安全， 一种灵敏、廉价的方法，用于HF患者的无创容量状态监测。

Volume overload (congestion) occurs in patients with heart failure (HF) and is the leading cause of hospitalization in the elderly worldwide. Unfortunately, clinical signs and symptoms; laboratory values; and existing diagnostic tools are unreliable in providing accurate assessment of volume status. Using a unique physiologic signal, Non-Invasive Venous waveform Analysis (NIVA), VoluMetrix has developed a proprietary device (“VasaWatch”) and algorithm designed for monitoring volume status in HF patients. Proof of concept data in humans and experimental animal models, demonstrate that VasaWatch provides a reliable indication of intravascular volume status. The studies in this Fast Track SBIR will establish that VasaWatch is a safe, sensitive, inexpensive method for non-invasive volume status monitoring in patients with HF.