Eunice Kennedy Shriver NICHD Cooperative Multicenter Neonatal Research Network

 描述(由申请者提供)：这份申请突显了埃默里大学新生儿学部继续参与尤尼斯·肯尼迪·施莱弗NICHD多中心新生儿研究网络(NRN)24年的能力和承诺。详细介绍了埃默里健全的研究环境和该司积极的研究计划。我们在亚特兰大大都市的三家医院提供医疗服务并招募研究患者，其中包括：佐治亚州最大的格雷迪纪念医院；高风险孕产妇中心埃默里大学医院中城；以及第三转诊中心埃格尔斯顿的亚特兰大儿童医疗保健。这些网站每年照顾超过7,000名新生儿、1,750名新生儿入院和350例手术病例，人口多样化，病理异常，为解决重要的研究问题提供了绝佳的环境。新生儿科与埃默里和其他机构的其他儿科和科室进行了有效的协作。我们独特的优势是与疾病控制和预防中心的科学家建立了密切的学术联系，并在以下领域拥有强大的机构研究实力和项目：神经科学；发育肺生物学；移植/免疫学；传染病，特别是新生儿-围产期感染；药物和疫苗开发；粘膜免疫/肠道炎症；癌症和血液疾病；心血管发育和生物学；以及新生儿-围产期医学的流行病学研究和临床试验。作为对RFA的回应，我们的赠款申请审查了Emory在NRN中的参与情况；临床和研究设施；产科和新生儿合作；医务人员和支持服务；可用于临床研究的多样化人口；母婴医学；围产期数据收集；高风险婴儿随访计划；我们经验丰富的研究护士；新生儿研究和人员配备；以及Emory和Atlanta的特殊研究优势。David Carlton博士自2007年起担任候补PI，将作为PD/PI领导Emory站点。他是一位公认的肺部生物学家，具有协作工作的能力。 与其他研究人员、临床中心和科学团体合作。Lucky Jain博士是一位在肺液清除领域享有盛誉的临床研究员和国际知名研究员，他将重新担任PD/PI的候补角色。艾拉·亚当斯-查普曼博士，NRN后续PI，是一位为NRN做出重要贡献的知名后续调查员。Carlton博士和我们整个新生儿科都热衷于致力于NRN，并通过合作的NRN研究促进新生儿医学的发展。

 DESCRIPTION (provided by applicant): This application highlights the ability and commitment of Emory University's Division of Neonatology to continue its 24 year participation in the Eunice Kennedy Shriver NICHD Multicenter Neonatal Research Network (NRN). An overview of the robust research environment at Emory and the active research programs of the Division are detailed. We provide medical services and recruit study patients at three hospitals in metropolitan Atlanta, which include: Grady Memorial Hospital, the largest hospital in Georgia; Emory University Hospital Midtown, a high-risk maternal center; and Children's Healthcare of Atlanta at Egleston, a tertiary referral center. These sites care for over 7,000 births, 1,750 neonatal admissions and 350 surgical cases per year, with a diverse population with unparalleled pathology, providing an excellent setting to address important research questions. The Neonatal Division has collaborated effectively with the other Pediatric divisions and departments at Emory and at other institutions. A unique strength is our close academic link to scientists at the Centers for Disease Control and Prevention as well as strong institutional research strength and programs in the neurosciences; developmental lung biology; transplant/immunology; infectious diseases, particularly neonatal-perinatal infections; drug and vaccine development; mucosal immunity/intestinal inflammation; cancer and blood disorders; cardiovascular development and biology; and epidemiologic studies and clinical trials in neonatal-perinatal medicine. In response to the RFA, our grant application reviews Emory's participation in the NRN; clinical and research facilities; obstetrical and neonatal cooperation; medical staff and support services; the diverse population available for clinical research; maternal-fetal medicine; perinatal data collection; the high-risk infant follow-up program; our superb experienced research nurses; neonatologist research and staffing; and special research strengths of Emory and Atlanta. Dr. David Carlton, Alternate-PI since 2007, will lead the Emory site as PD/PI. He is a recognized lung biologist, with demonstrated ability to work collaboratively with other investigators, clinical centers, and scientific groups. Dr. Lucky Jain, an established clinical investigator and internationally renowned researcher in the area of lung fluid clearance, will resume his role as alternate PD/PI. Dr. Ira Adams-Chapman, NRN follow-up PI, is an established follow-up investigator who has made important contributions to the NRN. Dr. Carlton and our entire Neonatal Division are enthusiastic in their commitment to the NRN and the advancement of neonatal medicine through collaborative NRN studies.