Eunice Kennedy Shriver NICHD Cooperative Multicenter Neonatal Research Network

尤尼斯·肯尼迪·施赖弗 (Eunice Kennedy Shriver) NICHD 合作多中心新生儿研究网络

• 批准号: 10348090
• 负责人: Ravi Mangal Patel
• 金额: $ 23.32万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10348090
• 关键词: Address; Administrator; Admission activity; Advocate; Applications Grants; Area; Biology; Birth; Cardiovascular system; Caring; Centers for Disease Control and Prevention (U.S.); Cesarean section; Child; Child Health; Child Welfare; Child health care; Childhood; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communicable Diseases; Communities; Country; Data Collection; Development; Discipline of obstetrics; Disease; Doctor of Philosophy; Environment; Faculty; Family; Financial Support; Fostering; Funding; Future; Goals; Grant; Gynecology; Health; Healthcare; Healthcare Systems; Hematological Disease; Hospitals; Immunology; Infant; Infrastructure; Institutes; Institution; International; Laboratories; Lead; Leadership; Letters; Link; Liquid substance; Lung; Malignant Neoplasms; Maternal-fetal medicine; Medical; Medical Staff; Medicine; Mission; Mucosal Immunity; Multicenter Neonatal Research Network; National Institute of Child Health and Human Development; Neonatal; Neonatal Mortality; Neonatology; Neurodevelopmental Impairment; Neurosciences; Newborn Infant; Nursing Research; Observational Study; Operative Surgical Procedures; Outcome; Pathology; Patients; Pediatrics; Peer Review; Perinatal; Perinatal Infection; Personal Satisfaction; Physiology; Population Heterogeneity; Premature Infant; Prevention; Process; Productivity; Progress Reports; Public Health Nursing; Publications; Research; Research Personnel; Research Priority; Research Project Grants; Risk Factors; Role; Science; Scientist; Services; Site; Sodium; Strategic Planning; Talents; Time; Training; Translating; Translational Research; Transplantation; United States National Institutes of Health; Universities; University Hospitals; Very Low Birth Weight Infant; Work; biomedical referral center; clinical care; clinical center; drug development; epidemiology study; experience; fetal; follow-up; high risk; high risk infant; improved; inflammatory disease of the intestine; innovation; interest; lung injury; maternal risk; medical schools; metropolitan; mortality; multidisciplinary; neonatal care; neonatal morbidity; pediatric department; perinatal medicine; professor; programs; public health relevance; recruit; research facility; response; success; survival outcome; vaccine development

 DESCRIPTION (provided by applicant): This application highlights the ability and commitment of Emory University's Division of Neonatology to continue its 24 year participation in the Eunice Kennedy Shriver NICHD Multicenter Neonatal Research Network (NRN). An overview of the robust research environment at Emory and the active research programs of the Division are detailed. We provide medical services and recruit study patients at three hospitals in metropolitan Atlanta, which include: Grady Memorial Hospital, the largest hospital in Georgia; Emory University Hospital Midtown, a high-risk maternal center; and Children's Healthcare of Atlanta at Egleston, a tertiary referral center. These sites care for over 7,000 births, 1,750 neonatal admissions and 350 surgical cases per year, with a diverse population with unparalleled pathology, providing an excellent setting to address important research questions. The Neonatal Division has collaborated effectively with the other Pediatric divisions and departments at Emory and at other institutions. A unique strength is our close academic link to scientists at the Centers for Disease Control and Prevention as well as strong institutional research strength and programs in the neurosciences; developmental lung biology; transplant/immunology; infectious diseases, particularly neonatal-perinatal infections; drug and vaccine development; mucosal immunity/intestinal inflammation; cancer and blood disorders; cardiovascular development and biology; and epidemiologic studies and clinical trials in neonatal-perinatal medicine. In response to the RFA, our grant application reviews Emory's participation in the NRN; clinical and research facilities; obstetrical and neonatal cooperation; medical staff and support services; the diverse population available for clinical research; maternal-fetal medicine; perinatal data collection; the high-risk infant follow-up program; our superb experienced research nurses; neonatologist research and staffing; and special research strengths of Emory and Atlanta. Dr. David Carlton, Alternate-PI since 2007, will lead the Emory site as PD/PI. He is a recognized lung biologist, with demonstrated ability to work collaboratively with other investigators, clinical centers, and scientific groups. Dr. Lucky Jain, an established clinical investigator and internationally renowned researcher in the area of lung fluid clearance, will resume his role as alternate PD/PI. Dr. Ira Adams-Chapman, NRN follow-up PI, is an established follow-up investigator who has made important contributions to the NRN. Dr. Carlton and our entire Neonatal Division are enthusiastic in their commitment to the NRN and the advancement of neonatal medicine through collaborative NRN studies.

 描述（由申请人提供）：本申请突出了埃默里大学新生儿科的能力和承诺，继续其24年的参与尤尼斯肯尼迪施莱佛NICHD多中心新生儿研究网络（NRN）。埃默里大学强大的研究环境和该司的积极研究计划的概述进行了详细说明。我们在亚特兰大大都市的三家医院提供医疗服务并招募研究患者，其中包括：格雷迪纪念医院，格鲁吉亚最大的医院;埃默里大学医院市中心，一个高风险的孕产妇中心;和亚特兰大埃格尔斯顿儿童保健中心，三级转诊中心。这些研究中心每年护理超过7，000名新生儿，1，750名新生儿入院和350例手术病例，具有无与伦比的病理学的多样化人口，为解决重要的研究问题提供了绝佳的环境。新生儿部与埃默里大学和其他机构的其他儿科部门进行了有效的合作。一个独特的优势是我们与疾病控制和预防中心的科学家密切的学术联系，以及强大的机构研究实力和神经科学计划;发育肺生物学;移植/免疫学;传染病，特别是围产期感染;药物和疫苗开发;粘膜免疫/肠道炎症;癌症和血液疾病;心血管发育和生物学;以及围产期医学的流行病学研究和临床试验。在回应RFA，我们的赠款申请审查埃默里大学的参与NRN;临床和研究设施;产科和新生儿合作;医务人员和支持服务;可用于临床研究的不同人群;母胎医学;围产期数据收集;高危婴儿随访计划;我们的高超经验丰富的研究护士;产科医生的研究和人员配备;以及埃默里和亚特兰大的特殊研究优势。大卫卡尔顿博士，自2007年以来的替代PI，将领导埃默里研究中心作为PD/PI。他是一位公认的肺部生物学家，具有良好的协作能力 与其他研究人员、临床中心和科学团体合作。Lucky Jain博士是一位成熟的临床研究者，也是肺液清除领域的国际知名研究者，他将继续担任替代PD/PI。伊拉·亚当斯-查普曼博士，NRN随访PI，是一名成熟的随访研究者，为NRN做出了重要贡献。Carlton博士和我们的整个新生儿部门都热衷于他们对NRN的承诺，并通过合作NRN研究促进新生儿医学的发展。