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Imaging Core

成像核心

基本信息

批准号：
9922633
负责人：
ARTHUR W TOGA
金额：
$ 47.85万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-01 至 2025-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/9922633
关键词：
Alzheimer&apos s Disease Alzheimer&apos s disease diagnosis Alzheimer&apos s disease risk Archives Biomedical Engineering Blood Vessels Cerebrovascular system Collaborations Communities Data Data Collection Dementia Development Early Diagnosis Family Practice Functional disorder Genomics Gerontology Goals Grain Human Hybrids Image Imaging Device Imaging Techniques Impaired cognition MRI Scans Magnetic Resonance Imaging Medicine Metabolic Mission Modernization Neurology Neurosciences Noise Pathogenesis Pharmacology Physical therapy Physics Physiologic pulse Positron-Emission Tomography Postdoctoral Fellow Protocols documentation Psychology Quality Control Research Research Design Research Personnel Resources Risk Factors Risk Reduction Role Scanning Signal Transduction Standardization Structure Training Training and Education Vascular Cognitive Impairment Vascular Diseases analytical tool base cohort connectome contrast enhanced data dissemination data management data quality graduate student neuroimaging neurovascular novel open data protocol development recruit repository research study statistics training opportunity vascular contributions vascular risk factor vector

项目摘要

PROJECT ABSTRACT As a part of the USC Alzheimer Disease Research Center competitive renewal, the Imaging Core will continue to serve the overall mission to provide high-quality MR and PET imaging resources to the local and broader AD research community. The ADRC Imaging Core will provide core resources, including MR physics and PET expertise, multi-scanner sequence and protocol development, image data quality control and management, research collaboration, and a global framework for conducting AD neuroimaging research. The Imaging Core is led by a well-integrated and collaborative team, including Arthur Toga (Core Leader), Judy Pa (Core Co-Leader), Meredith Braskie, Danny JJ Wang, Nasim Sheikh-Bahaei, and Paul Thompson, who together provide expertise in vascular, functional, and structural imaging and its analyses for 3T and 7T MRI, and PET. We propose 5 specific aims that provide an imaging framework for all ADRC projects; perform high quality control of all imaging data; develop technical and scientific approaches for ultra- high field 7T MRI; assist in PET protocol development and quality control; and conduct education and training in modern imaging techniques. Taken together, these goals will serve the USC ADRC’s unifying scientific theme of vascular contributions to Alzheimer disease: risk factors, neurovascular and metabolic mechanisms, and risk reduction.

项目摘要