Native Research and Resource Core
本土研究和资源核心
基本信息
- 批准号:9921710
- 负责人:
- 金额:$ 17.1万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-06-01 至 2025-04-30
- 项目状态:未结题
- 来源:
- 关键词:AddressAlaska NativeAlzheimer&aposs DiseaseAlzheimer&aposs disease related dementiaAmerican IndiansCaregiversClinicalCodeCollaborationsCommunitiesCongressesDataEducational workshopEnrollmentFinancial compensationFocus GroupsFundingGoalsGovernmentHealthHelicopterIndividualInterviewKnowledgeLeadLearningLife ExpectancyMagnetic Resonance ImagingMass MediaModelingNational Institute on AgingNative-BornParticipantPerceptionPhasePopulationPovertyProtocols documentationPublicationsQualitative ResearchReportingResearchResearch PersonnelResourcesRewardsRuralServicesTimeTranslatingTribesUniversitiesWashingtonWorkbiological heterogeneitycommunity based participatory researchcommunity involvementdata sharingdesigneffectiveness evaluationexpectationexperienceflyhealth disparityinformantinnovationinterestmembernative elderneglectneuroimagingprogramspromoterrecruitrepositoryrural Americanstribal Nation
项目摘要
Abstract
Many American Indians and Alaska Natives (AI/ANs) view research with skepticism and mistrust, in part because
research has historically been done in or on communities rather than with them. As a result, partnerships with
Native communities are challenged by distrust of scientific research, misunderstandings, and competing priorities
between researchers and community members. We have shown that factors significantly increasing odds of
participation in research include conduct of the study by a tribal entity, involving the community in its design,
having an AI/AN project lead, offering compensation, focusing on problems important to the community, and
providing services. Inclusion of disparity populations in Alzheimer's disease and related dementias (ADRD)
research has emerged as a priority for the National Plan to Address Alzheimer's Disease. Yet, the Clinical Cores
(CC) of the Alzheimer's Disease Research Centers (ADRCs) have recruited only 248 (0.06%) AI/ANs over 30+
years; the University of Washington ADRC has enrolled only 3 AI/ANs during this time. CC participants are
evaluated according to a single protocol, which may hinder enrolling AI/ANs if the content, approach, and
compensation are not salient to, or aligned with, their experiences, expectations, or culture. Partnerships for
Native Health, one of the nation's largest groups conducting health research in Native communities, has
collaborated with the UW ADRC for the past 5 years. We are now poised to enroll AI/ANs into the Native
Research and Resource Core (NRRC) by conducting 2 complementary activities. In PY01-02, we will conduct
qualitative research with AI/AN stakeholders to review the standard UW CC protocol and identify facilitators and
barriers to participation. Next, the CC will help design alternative protocols for use in the NRRC. With the National
Congress on American Indians, the largest organization serving tribal governments, we will host 4 workshops
that assemble investigators and urban and tribal nation representatives to discuss tribal-academic research
partnerships, including possible strategies for data-sharing. In PY03-05, we will use the alternative protocols
developed in Phase 1 to recruit AI/ANs into NRRC. Our Specific Aims are to: 1) Conduct focus groups and key
informant interviews with urban and rural AI/AN elders and other stakeholders to understand barriers to and
promoters of participation in the UW CC and create alternative NRRC protocols that retain essential CC
components; 2) Conduct workshops with stakeholders in tribal-academic partnerships to explore strategies that
might allow data collected from AI/AN participants in the NRRC to be shared with the National Alzheimer's
Coordinating Center; 3) Evaluate the effectiveness of the alternative, culturally informed protocols for increasing
AI/AN recruitment into the NRRC; and 4) Work with ADRC Cores to promote NRRC participation, appraise
protocols, conduct examinations, perform neuroimaging, and assign UW identification codes to participants.
NRRC is a first step toward remedying the underrepresentation of AI/ANs in ADRD research, addressing
decades of neglect and recent calls for diversity. This effort could serve as a resource and a model for all ADRCs.
摘要
许多美国印第安人和阿拉斯加原住民(AI/AN)以怀疑和不信任的态度看待研究,部分原因是
研究历来是在社区内或对社区进行的,而不是与社区一起进行的。因此,与
土著社区面临着对科学研究的不信任、误解和相互竞争的优先事项的挑战
研究人员和社区成员之间。我们已经表明,显著增加
参与研究包括由部落实体进行研究,让社区参与研究设计,
有一个AI/AN项目负责人,提供补偿,专注于对社区重要的问题,
提供服务。纳入阿尔茨海默病和相关痴呆(ADRD)的差异人群
研究已经成为国家计划的优先事项,以解决阿尔茨海默氏症。然而,临床核心
(CC)的阿尔茨海默病研究中心(ADRC)仅招募了248名(0.06%)30岁以上的AI/AN
年;华盛顿大学ADRC在此期间仅招募了3名AI/AN。CC参与者是
根据单一方案进行评估,如果内容、方法和
薪酬与他们的经验、期望或文化并不突出,也不一致。伙伴关系
土著健康,全国最大的团体之一,在土著社区进行健康研究,
在过去的五年里,我与UW ADRC合作。我们现在准备将AI/AN注册到Native
研究和资源核心(NRRC),开展2项互补活动。在PY 01 -02,我们将进行
与AI/AN利益相关者进行定性研究,以审查标准UW CC协议并确定促进者,
参与的障碍。接下来,CC将帮助设计用于NRRC的替代协议。与国家
美国印第安人大会,最大的服务于部落政府的组织,我们将举办4个研讨会
该组织聚集了调查人员和城市及部落民族代表,讨论部落学术研究
伙伴关系,包括可能的数据共享战略。在PY 03 -05中,我们将使用替代方案
在第一阶段开发,以招募AI/AN进入NRRC。我们的具体目标是:1)进行焦点小组和关键
与城市和农村的人工智能/人工智能老年人和其他利益攸关方进行信息访谈,以了解
促进参与UW CC,并创建保留基本CC的替代NRRC协议
2)与部落-学术伙伴关系中的利益攸关方举办讲习班,探讨
可能允许从NRRC中的AI/AN参与者收集的数据与国家阿尔茨海默氏症
3)评估替代的、文化上知情的协议的有效性,以增加
4)与ADRC核心合作,促进NRRC的参与,评估
协议,进行检查,进行神经成像,并为参与者分配UW识别代码。
NRRC是纠正ADRD研究中AI/AN代表性不足的第一步,
几十年的忽视和最近对多样性的呼吁。这一努力可以成为所有发展成果中心的一种资源和模式。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
DEDRA S BUCHWALD其他文献
DEDRA S BUCHWALD的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('DEDRA S BUCHWALD', 18)}}的其他基金
Community Health and Aging in Native Groups of Elders Resource Center for Minority Aging Research (CHANGE RCMAR)
土著老年人群体的社区健康和老龄化少数民族老龄化研究资源中心 (CHANGE RCMAR)
- 批准号:
10730130 - 财政年份:2023
- 资助金额:
$ 17.1万 - 项目类别:
相似海外基金
NNA Research: Collaborative Research: Towards resilient water infrastructure in Alaska Native communities through knowledge co-production
NNA 研究:合作研究:通过知识共同生产为阿拉斯加原住民社区打造具有复原力的水基础设施
- 批准号:
2220518 - 财政年份:2023
- 资助金额:
$ 17.1万 - 项目类别:
Standard Grant
NNA Research: Collaborative Research: Towards resilient water infrastructure in Alaska Native communities through knowledge co-production
NNA 研究:合作研究:通过知识共同生产为阿拉斯加原住民社区打造具有复原力的水基础设施
- 批准号:
2220516 - 财政年份:2023
- 资助金额:
$ 17.1万 - 项目类别:
Standard Grant
NNA Research: Collaborative Research: Towards resilient water infrastructure in Alaska Native communities through knowledge co-production
NNA 研究:合作研究:通过知识共同生产为阿拉斯加原住民社区打造具有复原力的水基础设施
- 批准号:
2220517 - 财政年份:2023
- 资助金额:
$ 17.1万 - 项目类别:
Standard Grant
Deep molecular and cellular profiling of colorectal cancer tumor and immune microenvironment in Alaska Native people
阿拉斯加原住民结直肠癌肿瘤和免疫微环境的深入分子和细胞分析
- 批准号:
10651205 - 财政年份:2023
- 资助金额:
$ 17.1万 - 项目类别:
Development of an Instrument for Assessment of Indigenous Historical Trauma as a Social Determinant of Health Among American Indian/Alaska Native Populations
开发一种评估土著历史创伤作为美洲印第安人/阿拉斯加原住民健康社会决定因素的工具
- 批准号:
10736011 - 财政年份:2023
- 资助金额:
$ 17.1万 - 项目类别:
Understanding cancer and comorbidities among American Indian and Alaska Native people
了解美洲印第安人和阿拉斯加原住民的癌症和合并症
- 批准号:
10722119 - 财政年份:2023
- 资助金额:
$ 17.1万 - 项目类别:
Urban American Indian/Alaska Native Cultural Eating Values and Behaviors: Community-based, mixed methods research to inform a holistic and culturally-informed diabetes prevention intervention program
城市美洲印第安人/阿拉斯加原住民文化饮食价值观和行为:基于社区的混合方法研究,为全面且文化丰富的糖尿病预防干预计划提供信息
- 批准号:
10679529 - 财政年份:2023
- 资助金额:
$ 17.1万 - 项目类别:
Planning Grant: Moving Forward Together - Transforming Arctic Geosciences for Alaska Native Sovereignty and Science
规划拨款:共同前进 - 为阿拉斯加原住民主权和科学转变北极地球科学
- 批准号:
2228064 - 财政年份:2023
- 资助金额:
$ 17.1万 - 项目类别:
Standard Grant
Alaska Native Communities Advancing Vaccine Uptake
阿拉斯加原住民社区促进疫苗接种
- 批准号:
10504537 - 财政年份:2022
- 资助金额:
$ 17.1万 - 项目类别:
Alaska Native Family-Based, Financial Incentives Intervention for Smoking Cessation: an RCT
基于阿拉斯加原住民家庭的戒烟经济激励干预措施:随机对照试验
- 批准号:
10612408 - 财政年份:2022
- 资助金额:
$ 17.1万 - 项目类别: