FLYBASE: A DROSOPHILA GENOMIC AND GENETIC DATABASE

FlyBASE：摘要 在过去的24年里，FlyBase为果蝇的遗传和 基因组数据，使研究人员能够进一步研究。果蝇是最好的模特之一 并在阐明人类遗传病的病因方面提供具有成本效益的帮助。FlyBase有 三个主要目标。1.继续整理与果蝇研究有关的文献和试剂，以便 研究人员可以继续依靠FlyBase找到该领域的最新创新。我们将优先安排策展 与基因表达、细胞功能、信号通路和人类疾病相关的数据集，以及 以直观、集成、易于搜索的格式显示信息。2.将FlyBase的效用提高到 人类遗传学和人口遗传学社区，通过管理和整合相关数据集，以及 开发工具，以便更好地访问这些丰富的数据。作为基因组联盟的成员 研究(AGR)，FlyBase将与其他模式生物数据库(MODS)合作，将数据集和 开发工具以实现跨物种分析。这一努力将对苍蝇群落产生重大影响， 加快发展人类疾病模型。3.促进更全面的分析和 方法，FlyBase将继续扩大其作为集成和展示大规模 研究、转录组和蛋白质组学数据集。此外，FlyBase将改进工具的访问和显示 在社区内可用，并结合了最有用的数据集和工具来可视化复杂 数据集，使更多的研究人员能够采取更全球化的方法进行他们的基因研究。 好了！

FLYBASE: SUMMARY For the past twenty-four years, FlyBase has provided a centralized resource for Drosophila genetic and genomic data to enable researchers to further their research. Drosophila is one of the premier model organisms and provides cost-effective help in elucidating the etiology of human genetic diseases. FlyBase has three main goals. 1. To continue curation of literature and reagents relevant to Drosophila research, so that researchers can continue to rely on FlyBase to find the latest innovations in the field. We will prioritize curation of data sets relevant to gene expression, cellular functions, signaling pathways, and human diseases, and display the information in an intuitive, integrated, readily searchable format. 2. To improve FlyBase's utility to the human genetics and population genetics communities, by curating and integrating relevant data sets, and developing tools that enable better access to this wealth of data. As a member of the Alliance for Genomic Research (AGR), FlyBase will work with other Model Organism Databases (MODs) to integrate data sets and develop tools to enable cross-species analyses. This effort will have a major impact on the fly community, accelerating the development of models of human diseases. 3. To facilitate more integrative analyses and approaches, FlyBase will continue to expand its utility as a platform for integrating and displaying large-scale studies, transcriptomics and proteomics data sets. In addition, FlyBase will improve access and display of tools available within the community, and incorporate the most useful data sets and tools for visualizing complex data sets to enable more researchers to take a more global approach to their genetic research. !