权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Kentucky Women's Justice Community Opioid Innovation Network (WJCOIN)

肯塔基州妇女司法社区阿片类药物创新网络 (WJCOIN)

基本信息

批准号：
9978015
负责人：
Michele Staton
金额：
$ 178.34万
依托单位：
UNIVERSITY OF KENTUCKY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-15 至 2024-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9978015
关键词：
Affect Benefits and Risks Caring Climate Clinical Clinical Research Communities Cost Analysis Criminal Justice Death Rate Development Drug abuse Drug usage Effectiveness Exposure to Funding Goals Health Services Accessibility High Risk Woman Hybrids Imprisonment Intervention Jail Justice Kentucky Lead Leadership Life Link Maintenance Methods Modeling National Institute of Drug Abuse Opioid Outcome Overdose Perception Pharmaceutical Preparations Physicians Positioning Attribute Public Health Quality of Care Randomized Readiness Recording of previous events Recovery Relapse Reporting Research Research Personnel Rewards Safety Savings Self Medication Services Site System Time Treatment Cost United States National Institutes of Health Universities Woman arm base community reentry compare effectiveness comparison group cost cost effectiveness cost-effectiveness ratio effectiveness implementation trial experience follow-up high risk improved incremental cost-effectiveness innovation innovative technologies intervention cost member men opioid epidemic opioid exposure opioid injection opioid mortality opioid use disorder overdose death pain sensitivity peer prescription opioid programs recidivism safety outcomes telehealth treatment as usual

项目摘要

ABSTRACT The opioid crisis continues to ravage US communities with overdose deaths at an all-time high. Women are disproportionately affected by the opioid crisis due to increased pain sensitivity, physician prescribing practices, and self-medication, as well as a faster trajectory from opioid exposure to the development of opioid use disorder (OUD). The opioid overdose death rate among women has risen 492% since 1999, a higher rate than men (404%). However, research on approaches to increase initiation of life-saving medications for opioid use disorder (MOUD) among women is limited. The University of Kentucky proposes to establish the Women’s Clinical Research Center as part of the NIDA Justice Community Opioid Innovation Network (W-JCOIN). The overall goal of the W-JCOIN is to increase initiation and maintenance of MOUD among high-risk justice-involved women in the transition from jail to the community to reduce opioid relapse and overdose. As part of this NIH collaborative network, the W-JCOIN will lead a type 1 hybrid effectiveness and implementation trial to examine an innovative MOUD pre-treatment model using telehealth (alone and in combination with peer navigators) for justice-involved women in transition from jail to the community in 6 experimental and 3 comparison (Services as Usual-SAU) sites. The following aims guide the study: (1) Compare the effectiveness of MOUD Pre-Treatment Telehealth (alone versus in combination with Peer Navigators) to increase MOUD initiation and maintenance among high- risk, justice-involved women in the community after release relative to services as usual (SAU). (2) Estimate the incremental cost and cost effectiveness of MOUD Pre-Treatment Telehealth (alone and in combination with Peer Navigators) relative to SAU for high-risk justice involved women with OUD in achieving desired changes in clinical, public health, and public safety outcomes over one-year post-release. (3) Examine temporal changes in key implementation constructs hypothesized by the EPIS framework to influence successful innovation implementation. This application is supported by an experienced team of NIH funded investigators with a track record of engaging in NIH justice research cooperative. The research team is well-positioned to be active members of the JCOIN network to rapidly conduct studies on quality care for OUD, with special focus on underserved and understudied justice-involved women. The KY W-JCOIN has the potential for significant impact on the OUD treatment field by contributing empirical evidence on the effectiveness and implementation of innovative technologies to increase initiation and maintenance of life-saving medications during a critical, high-risk time of community re-entry among vulnerable, justice-involved women in both urban and non-urban communities. The long-term goal of this research is to increase the capacity for the justice system to respond to the opioid crisis through increased access to treatment to reduce opioid relapse and overdose.

摘要