Kentucky Women's Justice Community Opioid Innovation Network (WJCOIN)

肯塔基州妇女司法社区阿片类药物创新网络 (WJCOIN)

• 批准号: 10616702
• 负责人: Michele Staton
• 金额: $ 172.35万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10616702
• 关键词: Affect; Benefits and Risks; Climate; Clinical; Clinical Research; Communities; Community Healthcare; Cost Analysis; Criminal Justice; Death Rate; Development; Drug abuse; Drug usage; Effectiveness; Eligibility Determination; Exposure to; Funding; Goals; Health Services Accessibility; High Risk Woman; Imprisonment; Intervention; Jail; Justice; Kentucky; Lead; Leadership; Life; Link; Maintenance; Methods; Modeling; National Institute of Drug Abuse; Opioid; Outcome; Overdose; Perception; Persons; Pharmaceutical Preparations; Physicians; Positioning Attribute; Public Health; Quality of Care; Randomized; Recording of previous events; Recovery; Relapse; Reporting; Research; Research Personnel; Rewards; Safety; Self Medication; Services; Site; System; Time; Treatment Cost; United States National Institutes of Health; Universities; Woman; arm; community reentry; compare effectiveness; comparison group; cost; cost effectiveness; cost-effectiveness ratio; effectiveness/implementation trial; experience; follow-up; high risk; improved; incremental cost; incremental cost-effectiveness; innovation; innovative technologies; intervention cost; medication for opioid use disorder; member; men; opioid epidemic; opioid exposure; opioid injection; opioid mortality; opioid use disorder; organizational readiness; overdose death; pain sensitivity; peer; programs; recidivism; safety outcomes; services as usual; telehealth; treatment as usual

ABSTRACT The opioid crisis continues to ravage US communities with overdose deaths at an all-time high. Women are disproportionately affected by the opioid crisis due to increased pain sensitivity, physician prescribing practices, and self-medication, as well as a faster trajectory from opioid exposure to the development of opioid use disorder (OUD). The opioid overdose death rate among women has risen 492% since 1999, a higher rate than men (404%). However, research on approaches to increase initiation of life-saving medications for opioid use disorder (MOUD) among women is limited. The University of Kentucky proposes to establish the Women’s Clinical Research Center as part of the NIDA Justice Community Opioid Innovation Network (W-JCOIN). The overall goal of the W-JCOIN is to increase initiation and maintenance of MOUD among high-risk justice-involved women in the transition from jail to the community to reduce opioid relapse and overdose. As part of this NIH collaborative network, the W-JCOIN will lead a type 1 hybrid effectiveness and implementation trial to examine an innovative MOUD pre-treatment model using telehealth (alone and in combination with peer navigators) for justice-involved women in transition from jail to the community in 6 experimental and 3 comparison (Services as Usual-SAU) sites. The following aims guide the study: (1) Compare the effectiveness of MOUD Pre-Treatment Telehealth (alone versus in combination with Peer Navigators) to increase MOUD initiation and maintenance among high- risk, justice-involved women in the community after release relative to services as usual (SAU). (2) Estimate the incremental cost and cost effectiveness of MOUD Pre-Treatment Telehealth (alone and in combination with Peer Navigators) relative to SAU for high-risk justice involved women with OUD in achieving desired changes in clinical, public health, and public safety outcomes over one-year post-release. (3) Examine temporal changes in key implementation constructs hypothesized by the EPIS framework to influence successful innovation implementation. This application is supported by an experienced team of NIH funded investigators with a track record of engaging in NIH justice research cooperative. The research team is well-positioned to be active members of the JCOIN network to rapidly conduct studies on quality care for OUD, with special focus on underserved and understudied justice-involved women. The KY W-JCOIN has the potential for significant impact on the OUD treatment field by contributing empirical evidence on the effectiveness and implementation of innovative technologies to increase initiation and maintenance of life-saving medications during a critical, high-risk time of community re-entry among vulnerable, justice-involved women in both urban and non-urban communities. The long-term goal of this research is to increase the capacity for the justice system to respond to the opioid crisis through increased access to treatment to reduce opioid relapse and overdose.

摘要 阿片类药物危机继续肆虐美国社区，过量死亡人数创历史新高。女人是 由于疼痛敏感度增加而受到阿片类药物危机的不成比例的影响，医生开处方， 和自我用药，以及从阿片类药物暴露到阿片类药物使用障碍发展的更快轨迹 (有声)。自1999年以来，女性的阿片类药物过量死亡率上升了492%，高于男性 (404%)。然而，关于增加阿片类药物使用障碍救命药物启动的方法的研究 (Moud)在女性中的比例有限。肯塔基大学提议建立女性诊所 作为NIDA司法社区阿片类药物创新网络(W-JCOIN)的一部分的研究中心。整体而言 W-JCOIN的目标是在参与司法的高危妇女中增加MMOD的启动和维护 在从监狱到社区的过渡中，以减少阿片类药物的复发和过量。作为NIH合作项目的一部分 网络，W-JCOIN将领导类型1混合有效性和实施试验，以检查创新的 利用远程医疗(单独和与同行导航员相结合)进行司法介入的MOD前处理模式 从监狱过渡到社区的妇女在6个实验和3个比较中(服务照常--SAU) 网站。本研究的指导目标如下：(1)比较MOD治疗前远程健康的效果 (单独使用还是与Peer Navigator结合使用)，以增加高 风险、正义--相对于照常服务(SAU)，被释放后参与社区的妇女。(2)估算 Moud预处理远程医疗(单独和与Peer联合使用)的增量成本和成本效益 导航员)相对于SAU来说，高风险的正义让患有OUD的妇女参与实现预期的变化 发布后一年内的临床、公共卫生和公共安全结果。(3)检查时间变化 EPIS框架假设的影响成功创新的关键实施结构 实施。此应用程序由经验丰富的NIH资助的调查团队提供支持，该团队具有 参加美国国立卫生研究院司法研究合作社的记录。研究团队处于很好的地位，可以成为活跃的成员 JCOIN网络，以迅速开展对妇幼保健服务质量的研究，特别关注服务不足和 未得到充分研究的涉足司法的女性。KY W-JCOIN有可能对OUD产生重大影响 通过为治疗领域创新的有效性和实施提供经验证据 在关键的高风险时期增加救命药物的启动和维持的技术 城市和非城市社区的弱势、参与司法的妇女重返社区。这个 这项研究的长期目标是提高司法系统应对阿片类药物危机的能力。 通过增加获得治疗的机会来减少阿片类药物的复发和过量。

项目成果

Kentucky Women's Justice Community Opioid Innovation Network (JCOIN): A type 1 effectiveness-implementation hybrid trial to increase utilization of medications for opioid use disorder among justice-involved women.

• DOI: 10.1016/j.jsat.2021.108284
• 发表时间: 2021-09
• 期刊: Journal of substance abuse treatment
• 影响因子: 3.9
• 作者: Staton M;Webster JM;Leukefeld C;Tillson M;Marks K;Oser C;Bush HM;Fanucchi L;Fallin-Bennett A;Garner BR;McCollister K;Johnson S;Winston E
• 通讯作者: Winston E

Identifying and Treating Incarcerated Women Experiencing Substance Use Disorders: A Review.

• DOI: 10.2147/sar.s409944
• 发表时间: 2023
• 期刊: SUBSTANCE ABUSE AND REHABILITATION
• 影响因子: 1.8
• 作者: Staton, Michele;Tillson, Martha;Levi, Mary M.;Dickson, Megan;Webster, Matt;Leukefeld, Carl
• 通讯作者: Leukefeld, Carl

Scales for participant Alliance with Recovery Coach (SPARC): initial development and pilot test.

参与者与恢复教练联盟 (SPARC) 的规模：初始开发和试点测试。

• DOI: 10.1080/16066359.2023.2182881
• 发表时间: 2024
• 期刊: Addiction research & theory
• 影响因子: 2.9
• 作者: Fallin-Bennett,Amanda;Tillson,Martha;Webster,JMatthew;Oser,CarrieB;Becan,JenniferEdwards;Knight,Kevin;Byard,Jeremy;Staton,Michele
• 通讯作者: Staton,Michele

Providing peer navigation services to women with a history of opioid misuse pre- and post-release from jail: A program description.

• DOI: 10.1017/cts.2022.441
• 发表时间: 2022
• 期刊: JOURNAL OF CLINICAL AND TRANSLATIONAL SCIENCE
• 影响因子: 2.6
• 作者: Tillson, Martha;Fallin-Bennett, Amanda;Staton, Michele
• 通讯作者: Staton, Michele

Impacts of COVID-19 at the intersection of substance use disorder treatment and criminal justice systems: findings from three states.

• DOI: 10.1186/s40352-022-00184-8
• 发表时间: 2022-08-04
• 期刊: Health & justice
• 影响因子: 3.5