Dyadic yoga Program for Patients with Lung Cancer Undergoing Radiotherapy and their Family Caregivers
为接受放射治疗的肺癌患者及其家庭照顾者提供二元瑜伽课程
基本信息
- 批准号:9979799
- 负责人:
- 金额:$ 36.6万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-08-09 至 2023-07-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAdult ChildrenAffectBehavior TherapyBehavioralBehavioral SciencesBiological MarkersBloodCancer PatientCaregiversCaringDataDiseaseDistressDoseDyspneaEducationEffectivenessEmotionalEndocrineEvidence based interventionFamilyFamily CaregiverFatigueFutureGoalsHealth educationHydrocortisoneImmuneInflammatoryInterventionIntervention StudiesInvestigationKnowledgeLightLinkLiteratureLung diseasesMalignant NeoplasmsMalignant neoplasm of lungMeasuresMediatingMediator of activation proteinMeditationMental DepressionModelingNatureNon-Small-Cell Lung CarcinomaOutcomeParticipantPatientsPerformancePeriodicityPhysical FunctionPhysical PerformancePopulationPrognostic FactorQualitative MethodsQuality of CareQuality of lifeRadiation therapyRandomizedRandomized Controlled TrialsRehabilitation therapyReportingResearchRespiratory physiologySF-36SalivaSamplingScientific Advances and AccomplishmentsSiblingsSleep disturbancesSourceSpousesSubgroupSupportive careSymptomsTaxesTestingTreatment EfficacyUnited StatesVulnerable PopulationsWalkingWomanWorkYogaarmattentional controlbasebody-mindcancer therapycancer typecaregivingclinical careclinically relevantclinically significantcommon symptomcomparison groupcytokinedepressive symptomsdesignefficacy trialevidence baseexperiencefollow up assessmentimprovedinformal caregivinginnovationintervention effectmalignant breast neoplasmmenpatient populationphysical symptomprimary outcomeprogramspsychologicpsychological distresspsychological symptomsecondary outcomeskillssurvival predictionsymptom managementsymptomatic improvementtreatment durationtreatment optimizationtreatment planningtreatment responsetrial comparingusual care arm
项目摘要
PROJECT SUMMARY/ABSTRACT
Patients with lung cancer, the most prevalent cancer in United States affecting both men and women, experience
more debilitating physical and psychological symptoms than patients with other types of cancer. Common
symptoms include reduced lung function, dyspnea, fatigue, sleep disturbances, and depression compromising
their quality of life (QOL). In light of these symptoms, patients have a high need for care and support. Patients’
family caregivers are their most important and valued source of support and care; yet, caregiving is physically
and emotionally taxing. In fact, family caregivers report high rates of psychological distress, fatigue, and sleep
disturbances, which may compromise the quality of care they are able to provide to the patient. Given the
interdependent nature of QOL in families, poor caregiver QOL may undermine patient QOL. Therefore, there is
a need to established evidence-based dyadic supportive care programs targeting both patient and caregiver
outcomes. Based on the promising findings of our pilot data, we proposed to examine a dyadic yoga program
in patients with lung cancer (LC) and their family caregivers. To determine efficacy of a yoga program, the
proposed research will randomly assign patient-caregiver dyads to either a dyadic yoga or a dyadic education
group. Prior to randomization, both patients and caregivers will complete standard QOL measures. We will also
collect biomarkers from blood and saliva samples. Patients will complete objective measures of physical
performance. Based on their group assignment, dyads will either attend yoga sessions or health education
sessions together. Both groups will receive the same intervention exposure (15 sessions, 60 min each) over the
course of patients’ 6-week radiation treatment (RT) plans. During the treatment period, we will weekly assess
patients’ symptoms. At the end of RT, 1, 2, 3, and 6-months later, dyads in both groups will be re-assessed. At
the 3-month follow-up assessment, we will also collect qualitative samples to further understand participants’
experiences. The primary goal of this research is to demonstrate that, in the yoga group, patients will show
better objective physical performance both patients and caregivers will report greater improvements in QOL
compared to those in the dyadic education group. Secondary goals are to examine improvements in symptom
burden, endocrine and immune dysregulation and symptom management and if these improvements mediate
the physical function and QOL outcomes. Lastly, we examine factors that may moderate interventions effects,
which will inform future studies expanding this program of research. This project represents a major step towards
managing physical performance and QOL in lung cancer patients and their caregivers, a vulnerable yet
understudied population.
项目总结/摘要
肺癌是美国最常见的癌症,影响男性和女性,
比其他类型的癌症患者更虚弱的身体和心理症状。共同
症状包括肺功能下降、呼吸困难、疲劳、睡眠障碍和抑郁症,
生活质量(QOL)。鉴于这些症状,患者非常需要护理和支持。患者
家庭照顾者是他们最重要和最有价值的支持和照顾来源;然而,
和情感负担事实上,家庭照顾者报告说,心理困扰,疲劳和睡眠的比例很高
干扰,这可能会影响他们能够为患者提供的护理质量。鉴于
由于家庭生活质量的相互依赖性,照顾者生活质量差可能会损害患者的生活质量。因此有
需要建立以证据为基础的双重支持性护理计划,目标是患者和护理人员
结果。基于我们的试点数据的有希望的发现,我们建议检查一个二元瑜伽计划,
肺癌(LC)患者及其家庭照顾者。为了确定瑜伽课程的效果,
拟议的研究将随机分配病人-护理人员的二人组,要么是二人瑜伽,要么是二人教育
组在随机化之前,患者和护理人员都将完成标准QOL测量。我们还将
从血液和唾液样本中收集生物标志物。患者将完成客观的身体测量,
性能根据他们的小组任务,二人组将参加瑜伽课程或健康教育
会议在一起。两组将接受相同的干预暴露(15次,每次60分钟),
患者为期6周的放射治疗(RT)计划过程。在治疗期间,我们将每周评估
患者的症状。在RT结束时,1、2、3和6个月后,将重新评估两组中的二联体。在
在3个月的跟进评估中,我们亦会收集定性样本,以进一步了解参与者的
经验这项研究的主要目的是证明,在瑜伽组,患者将显示
更好的客观身体表现,患者和护理人员都将报告生活质量的更大改善
与二元教育组相比,次要目标是检查症状的改善
内分泌和免疫失调和症状管理,如果这些改善介导
身体功能和QOL结果。最后,我们研究了可能缓和干预效果的因素,
这将为未来的研究提供信息,扩大这一研究计划。该项目是朝着
管理肺癌患者及其护理人员的身体表现和生活质量,
被忽视的人群
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Kathrin Milbury其他文献
Kathrin Milbury的其他文献
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{{ truncateString('Kathrin Milbury', 18)}}的其他基金
Psycho-Spiritual Management for Patients with Advanced Cancer and their Family Caregivers
晚期癌症患者及其家庭照顾者的心理精神管理
- 批准号:
10734689 - 财政年份:2023
- 资助金额:
$ 36.6万 - 项目类别:
Simulation-Based Caregiving Skills Training for Family Members of High Grade Glioma Patients
高级别胶质瘤患者家属的模拟护理技能培训
- 批准号:
10509910 - 财政年份:2022
- 资助金额:
$ 36.6万 - 项目类别:
Simulation-Based Caregiving Skills Training for Family Members of High Grade Glioma Patients
高级别胶质瘤患者家属的模拟护理技能培训
- 批准号:
10693312 - 财政年份:2022
- 资助金额:
$ 36.6万 - 项目类别:
Parenting Intervention for Caregivers who Parent a Young Child while Caring for a Spouse with an Incurable Cancer.
针对在照顾患有无法治愈癌症的配偶时养育幼儿的护理人员的育儿干预。
- 批准号:
10301442 - 财政年份:2021
- 资助金额:
$ 36.6万 - 项目类别:
Improving Health Utilization and Quality of Life in Head and Neck Cancer Patients Undergoing Chemoradiation and their Family Caregivers
改善接受放化疗的头颈癌患者及其家庭护理人员的健康利用和生活质量
- 批准号:
10040568 - 财政年份:2020
- 资助金额:
$ 36.6万 - 项目类别:
Improving Health Utilization and Quality of Life in Head and Neck Cancer Patients Undergoing Chemoradiation and their Family Caregivers
改善接受放化疗的头颈癌患者及其家庭护理人员的健康利用和生活质量
- 批准号:
10684253 - 财政年份:2020
- 资助金额:
$ 36.6万 - 项目类别:
Improving Health Utilization and Quality of Life in Head and Neck Cancer Patients Undergoing Chemoradiation and their Family Caregivers
改善接受放化疗的头颈癌患者及其家庭护理人员的健康利用和生活质量
- 批准号:
10454943 - 财政年份:2020
- 资助金额:
$ 36.6万 - 项目类别:
Improving Health Utilization and Quality of Life in Head and Neck Cancer Patients Undergoing Chemoradiation and their Family Caregivers
改善接受放化疗的头颈癌患者及其家庭护理人员的健康利用和生活质量
- 批准号:
10263936 - 财政年份:2020
- 资助金额:
$ 36.6万 - 项目类别:
Dyadic yoga Program for Patients with Lung Cancer Undergoing Radiotherapy and their Family Caregivers
为接受放射治疗的肺癌患者及其家庭照顾者提供二元瑜伽课程
- 批准号:
9761506 - 财政年份:2018
- 资助金额:
$ 36.6万 - 项目类别:
Dyadic yoga Program for Patients with Lung Cancer Undergoing Radiotherapy and their Family Caregivers
为接受放疗的肺癌患者及其家人提供的二元瑜伽课程
- 批准号:
10214568 - 财政年份:2018
- 资助金额:
$ 36.6万 - 项目类别:
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