Reducing cannabis use for sleep among adults using medical cannabis

项目摘要/摘要 近年来，推动医用大麻合法化的运动在美国兴起 现在29个州和哥伦比亚特区都有条款允许将大麻用于医疗 理由。无论寻求医用大麻的具体原因是什么，接受评估的成年人 医用大麻认证报告与睡眠有关的严重问题以及频繁使用大麻 解决他们的睡眠问题。大麻用于睡眠是干预措施的一个关键潜在目标，因为 研究发现，在患有大麻使用障碍的人中，睡眠不佳是维持健康的障碍 大麻使用后的缓解。认知行为疗法(CBT)治疗失眠对个体非常有效 失眠与其他健康状况并存，包括物质使用障碍；然而， 疗效试验还没有具体评估它对那些使用大麻治疗失眠的人的好处。网络的影响 因此，CBT对医用大麻使用者的睡眠或大麻使用失眠的治疗尚不清楚。这个 该项目的目标是调整和定制一种电话传递的CBT，用于治疗失眠的成年人 (cbti-cb)，并评价这一干预措施的可接受性和可行性。定性的 并将收集定量数据，以完善现有的CBTi-CB协议，并进行试点测试 对使用医用大麻的成年人进行改进的干预。寻求医用大麻认证的成年人将 在等待预约时被接近，并对失眠和大麻使用情况进行筛查 睡吧。在最初的定性访谈和Beta测试之后，符合条件的参与者(N=40)将被随机分配到 CBTI-CB或睡眠教育控制(SE)条件，通过电话提供。参与者将提供自我 关于睡眠/失眠、功能和大麻使用情况的报告数据以及关于睡眠质量的客观数据将是 通过动作记录仪来测量。这项研究将评估自我报告和客观测量的睡眠的变化， 在治疗期间和治疗后18周期间使用大麻的功能和频率/数量-- 基线。研究目标的完成将提供未来全面动力所需的所有要素 CBTi-CB在医用大麻患者中长期疗效的随机试验。这一行 研究将是第一个评估以睡眠为重点的高效干预并确定其效果的研究 关于睡眠相关和非睡眠相关的大麻在非寻求治疗人群中的使用情况。

Project Summary/Abstract In recent years, the movement to promote the legalization of medical cannabis has grown in the United States and now 29 States and the District of Columbia have provisions that allow for the use of cannabis for medical reasons. Irrespective of the specific reasons for seeking medical cannabis, adults who have been evaluated for medical cannabis certification report significant sleep-related problems as well as frequent use of cannabis to address their sleep problems. Cannabis use for sleep is a key potential target for interventions given that prior research has found that, among individuals with cannabis use disorders, poor sleep is a barrier to sustained remission from cannabis use. Cognitive Behavioral Therapy (CBT) for insomnia is highly effective in individuals with insomnia comorbid with other health conditions, including substance use disorders; however, existing efficacy trials have not specifically evaluated its benefit in those who use cannabis for insomnia. The impact of CBT for insomnia on either sleep or cannabis use in medical cannabis users is, therefore, unknown. The objectives of this project are to adapt and tailor a telephone-delivered CBT for insomnia for adults who use medical cannabis (CBTi-CB) and to evaluate the acceptability and feasibility of this intervention. Qualitative and quantitative data will be collected to refine an existing CBTi-CB protocol and conduct a pilot test of the modified intervention in adults who use medical cannabis. Adults seeking certification for medical cannabis will be approached while waiting for their appointment and screened for insomnia as well as cannabis use for sleep. After initial qualitative interviews and beta testing, eligible participants (N = 40) will be randomized to CBTi-CB or Sleep Education Control (SE) condition, delivered over the telephone. Participants will provide self- report data on sleep/insomnia, functioning and cannabis use and objective data on sleep quality will be measured by actigraphy. The study will evaluate changes in self-reported and objectively measured sleep, functioning and frequency/quantity of cannabis use during treatment and over the course of 18-weeks post- baseline. Completion of the study aims will provide all of the elements required for a future fully-powered randomized trial of the longer-term efficacy of CBTi-CB among those with medical cannabis. This line of research would be the first to evaluate a highly effective sleep-focused intervention and determine the effects on sleep-related and non-sleep-related cannabis use in a non-treatment seeking population.