Targeting insomnia to improve outcomes in adults with problematic cannabis use

针对失眠,改善大麻使用问题成年人的结果

基本信息

  • 批准号:
    10557992
  • 负责人:
  • 金额:
    $ 73.24万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-09-15 至 2027-07-31
  • 项目状态:
    未结题

项目摘要

Cannabis use, heavy cannabis use, and cannabis-related problems are becoming increasingly common in the United States. Among those who use cannabis regularly, significant insomnia is common. For example, our data from 800 patients seeking medical cannabis indicate that insomnia is a chief comorbidity, with 80% of participants reporting that they regularly use cannabis to manage symptoms of insomnia. In addition, sleep problems are often a barrier to reducing cannabis use among those with Cannabis Use Disorders. Cognitive Behavioral Therapy for insomnia (CBTi) is highly effective in individuals with insomnia comorbid with other health conditions, including those with heavy and/or problematic use of substances; although it has not been fully tested in those with problematic cannabis use. In a recently-completed National Institute on Drug Abuse R34 randomized controlled pilot trial, our group found that, compared to a telemedicine-delivered Sleep Hygiene Education (SHE-TM) condition, a tailored telemedicine-delivered CBTi (CBTi-CB-TM) improved insomnia and daytime functioning and reduced cannabis use more during short-term follow-up among non- treatment-seeking adults using cannabis for sleep. In addition to important clinical questions related to the treatment of insomnia in those who use cannabis, the specific mechanisms linking heavy cannabis use and insomnia are poorly understood. We propose to evaluate whether a fundamental sleep regulatory system – homeostatic sleep drive – is dysregulated in subjects with problematic cannabis use and whether changes in this mechanism are associated with clinical outcomes. Thus, the aims of the proposed study are to recruit a sample of 200 adults with problematic cannabis use and insomnia to evaluate (1) the efficacy of CBTi-CB-TM vs. SHE-TM for sleep, cannabis use, and associated daytime symptoms and (2) the effects of CBTi-CB-TM on the homeostatic sleep system and its association with clinical outcomes. Building on the success of the recent R34, the proposed study will examine the longer-term outcomes associated with randomization to CBTi-CB-TM and utilize state-of-the-art measures of sleep homeostasis to examine the factors underlying the links between cannabis use, contents of the intervention, and objective sleep outcomes. These findings have important implications for understanding the relationship between cannabis use and sleep, as well as for identifying strategies to help improve outcomes in the large and growing group of individuals who report problematic cannabis use and sleep problems.
大麻使用、重度大麻使用以及与大麻相关的问题在美国越来越普遍

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

J. Todd Arnedt其他文献

J. Todd Arnedt的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('J. Todd Arnedt', 18)}}的其他基金

Targeting insomnia to improve outcomes in adults with problematic cannabis use
针对失眠,改善大麻使用问题成年人的结果
  • 批准号:
    10701928
  • 财政年份:
    2022
  • 资助金额:
    $ 73.24万
  • 项目类别:
Targeting sleep homeostasis to improve alcohol use disorder treatment outcomes
以睡眠稳态为目标,改善酒精使用障碍的治疗结果
  • 批准号:
    10019448
  • 财政年份:
    2019
  • 资助金额:
    $ 73.24万
  • 项目类别:
Targeting sleep homeostasis to improve alcohol use disorder treatment outcomes
以睡眠稳态为目标,改善酒精使用障碍的治疗结果
  • 批准号:
    9916265
  • 财政年份:
    2019
  • 资助金额:
    $ 73.24万
  • 项目类别:
Targeting sleep homeostasis to improve alcohol use disorder treatment outcomes
以睡眠稳态为目标,改善酒精使用障碍的治疗结果
  • 批准号:
    10487562
  • 财政年份:
    2019
  • 资助金额:
    $ 73.24万
  • 项目类别:
Targeting sleep homeostasis to improve alcohol use disorder treatment outcomes
以睡眠稳态为目标,改善酒精使用障碍的治疗结果
  • 批准号:
    10261433
  • 财政年份:
    2019
  • 资助金额:
    $ 73.24万
  • 项目类别:
Targeting sleep homeostasis to improve alcohol use disorder treatment outcomes
以睡眠稳态为目标,改善酒精使用障碍的治疗结果
  • 批准号:
    10687864
  • 财政年份:
    2019
  • 资助金额:
    $ 73.24万
  • 项目类别:
Reducing cannabis use for sleep among adults using medical cannabis
减少使用医用大麻的成年人用于睡眠的大麻使用
  • 批准号:
    9982845
  • 财政年份:
    2018
  • 资助金额:
    $ 73.24万
  • 项目类别:
Wireless sensor and telemedicine to screen for sleep apnea in elderly adults
无线传感器和远程医疗可筛查老年人的睡眠呼吸暂停
  • 批准号:
    9331733
  • 财政年份:
    2014
  • 资助金额:
    $ 73.24万
  • 项目类别:
Wireless sensor patch for reducing barriers to in-home sleep apnea screening
无线传感器贴片可减少家庭睡眠呼吸暂停筛查的障碍
  • 批准号:
    8723589
  • 财政年份:
    2014
  • 资助金额:
    $ 73.24万
  • 项目类别:
Wireless sensor and telemedicine to screen for sleep apnea in elderly adults
无线传感器和远程医疗可筛查老年人的睡眠呼吸暂停
  • 批准号:
    9202557
  • 财政年份:
    2014
  • 资助金额:
    $ 73.24万
  • 项目类别:

相似海外基金

Life outside institutions: histories of mental health aftercare 1900 - 1960
机构外的生活:1900 - 1960 年心理健康善后护理的历史
  • 批准号:
    DP240100640
  • 财政年份:
    2024
  • 资助金额:
    $ 73.24万
  • 项目类别:
    Discovery Projects
Development of a program to promote psychological independence support in the aftercare of children's homes
制定一项计划,促进儿童之家善后护理中的心理独立支持
  • 批准号:
    23K01889
  • 财政年份:
    2023
  • 资助金额:
    $ 73.24万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Integrating Smoking Cessation in Tattoo Aftercare
将戒烟融入纹身后护理中
  • 批准号:
    10452217
  • 财政年份:
    2022
  • 资助金额:
    $ 73.24万
  • 项目类别:
Integrating Smoking Cessation in Tattoo Aftercare
将戒烟融入纹身后护理中
  • 批准号:
    10670838
  • 财政年份:
    2022
  • 资助金额:
    $ 73.24万
  • 项目类别:
Aftercare for young people: A sociological study of resource opportunities
年轻人的善后护理:资源机会的社会学研究
  • 批准号:
    DP200100492
  • 财政年份:
    2020
  • 资助金额:
    $ 73.24万
  • 项目类别:
    Discovery Projects
Creating a National Aftercare Strategy for Survivors of Pediatric Cancer
为小儿癌症幸存者制定国家善后护理策略
  • 批准号:
    407264
  • 财政年份:
    2019
  • 资助金额:
    $ 73.24万
  • 项目类别:
    Operating Grants
Aftercare of green infrastructure: creating algorithm for resolving human-bird conflicts
绿色基础设施的善后工作:创建解决人鸟冲突的算法
  • 批准号:
    18K18240
  • 财政年份:
    2018
  • 资助金额:
    $ 73.24万
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists
Development of an aftercare model for children who have experienced invasive procedures
为经历过侵入性手术的儿童开发善后护理模型
  • 批准号:
    17K12379
  • 财政年份:
    2017
  • 资助金额:
    $ 73.24万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Development of a Comprehensive Aftercare Program for children's self-reliance support facility
为儿童自力更生支持设施制定综合善后护理计划
  • 批准号:
    17K13937
  • 财政年份:
    2017
  • 资助金额:
    $ 73.24万
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
Project#2 Extending Treatment Effects Through an Adaptive Aftercare Intervention
项目
  • 批准号:
    8742767
  • 财政年份:
    2014
  • 资助金额:
    $ 73.24万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了