Interventional and Translational Core

介入和转化核心

基本信息

批准号：
10183231
负责人：
Andrea L Cherrington
金额：
$ 21.89万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-04-01 至 2023-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10183231
关键词：
African American Alabama Ambulatory Care American Basic Science Behavior Behavioral Risk Factor Surveillance System Biomedical Research Body mass index Cardiometabolic Disease Cardiovascular Diseases Clinic Clinical Sciences Clinical Trials Collaborations Communities Complications of Diabetes Mellitus Comprehensive Health Care Consultations Continuity of Patient Care County Data Development Diabetes Mellitus Diabetes prevention Diet Education Ethnic Origin European Evaluation Funding Geography Goals Health Services Health Technology Health system Human Resources Infrastructure Intervention Intervention Trial Knowledge Low income Measurement Metabolic Diseases Methods Minority Groups Obesity Outcomes Research Outpatients Overweight Patients Physical Exercise Physical activity Population Prevalence Prevention Process Quality Control Quality of life Race Research Research Personnel Research Support Resources Role Rural Community Science Scientific Evaluation Services Structure Targeted Research Testing Translational Research Translations Underinsured Underserved Population Uninsured United States Universities Vascular Diseases Visit Weight Work analytical tool base bench to bedside built environment clinical center clinical practice community based research community setting cultural competence data acquisition data quality design diabetes management effectiveness research effectiveness testing efficacy testing glycemic control health care service health disparity health management high risk population innovation mHealth medication compliance multidisciplinary obese person population health prevent programs psychosocial quality assurance racial and ethnic disparities randomized trial recruit research study safety net social culture statistics therapy development tool trial design weight loss intervention

项目摘要

The overall goal of the Interventions and Translation Core (ITC) is to provide expertise, tools, and infrastructure to assist investigators with the development, implementation, and evaluation of culturally appropriate interventions. Our objective is to create new knowledge regarding the prevention and management of diabetes and cardiometabolic disease, with an emphasis on reducing health disparities. The ITC’s 3 specific aims are to: 1. Provide expert consultation for intervention development in diabetes prevention and management (e.g., interventions to optimize weight, exercise/physical activity, medication adherence, and/or glycemic control). This expertise will facilitate translation of basic science findings into efficacy and effectiveness testing of interventions in both clinic-based and community-based trials. 2. Provide expertise and tools for evaluation and data acquisition, including measurement, quality control, quality assurance, and analytic support, for research to prevent and manage diabetes. Services include methods and tools regarding diet, physical activity, mobile health technology, behavior, psychosocial and sociocultural parameters, built environment, quality of life, and cultural competence. 3. Design and facilitate culturally appropriate strategies to enhance the recruitment and retention of minorities and underserved populations in diabetes-related research studies, with emphasis on African American and rural communities. These core services are based on the expressed needs of funded DRC investigators, and methods will rely on validated, state-of-the-art approaches with a high priority placed on data quality control. The ITC will leverage existing infrastructure for recruitment and community-based research and make cutting edge expertise in intervention development, implementation and evaluation available to the DRC research base, promoting innovation and advancing the science of diabetes prevention and management.

干预措施和翻译核心（ITC）的总体目标是提供专业知识，工具和基础架构协助调查人员的发展，实施和评估文化适当的干预措施。我们的目标是创建有关糖尿病预防和管理的新知识和心脏代谢疾病，重点是减少健康差异。 ITC的3个具体目标是： 1。提供有关预防糖尿病和管理干预开发的专家咨询（例如优化体重，运动/体育锻炼，药物依从性和/或血糖控制的干预措施。这种专业知识将有助于将基础科学发现转化为有效性和有效性测试干预基于诊所和基于社区的试验。 2。提供评估和数据获取的专业知识和工具，包括测量，质量控制，质量保证和分析支持，以预防和管理糖尿病。服务包括有关饮食，体育锻炼，移动健康技术，行为，社会心理和的方法和工具社会文化参数，建立环境，生活质量和文化能力。 3。设计和促进文化上适当的策略，以增强少数民族的招募和保留以及与糖尿病有关的研究中服务不足的人群，重点是非裔美国人和农村社区。这些核心服务基于资助的刚果民主共和国调查人员的表达需求，方法将依靠经过验证，最先进的方法在数据质量控制方面具有很高的优先级。 ITC将利用现有用于招聘和基于社区研究的基础设施，并在 DRC研究基础可提供的干预开发，实施和评估，促进创新和推进糖尿病预防和管理科学。