Mechanism of Flightless I function in burn injury and scar formation
Mechanism of Flightless I function in burn injury and scar formation
批准号:
nhmrc : 565004
负责人:
A/Pr Ruth Arkell
金额:
$36.36万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2012-12-31
中文摘要
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英文摘要
Extensive scarring is a major clinical problem often resulting from burn injuries. We have previously shown that the cytoskeletal protein, Flightless I (FliI), is an important regulator of wound repair. We now plan to investigate whether FliI is also be the mechanistic link between cytoskeletal remodelling and induction of TGF-betas post-wounding leading to scar formation.
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依托单位:
海外基金