The Johns Hopkins NeuroHIV Comorbidities Scholar Program

约翰·霍普金斯大学 NeuroHIV 合并症学者计划

• 批准号: 10372044
• 负责人: AMANDA MARIA BROWN
• 金额: $ 44.89万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-05-10 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10372044
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Affect; Age; Aging; Area; Awareness; Baltimore; Basic Science; Bioinformatics; Brain; Cardiovascular Diseases; Central Nervous System Infections; Clinic; Clinical; Clinical Research; Communication; Communities; Country; Development; Development Plans; Doctor of Philosophy; Education; Educational Status; Epidemic; Family; First Generation College Students; Frequencies; Funding; Future; Gonorrhea; HIV; HIV Infections; HIV-1; Healthcare; High School Student; Incidence; Individual; Infection; Institutes; Intervention; Kidney Diseases; Knowledge; Learning; Literature; Liver diseases; Malignant Neoplasms; Mental Health; Mentors; Metabolic dysfunction; Motivation; NCI Scholars Program; National Institute of Mental Health; Neuraxis; Neurologic Dysfunctions; Neurosciences; Online Systems; Oral; Osteoporosis; Participant; Pathogenesis; Persons; Play; Population; Positioning Attribute; Prevalence; Psychiatry; Public Health Schools; Research; Research Personnel; Resources; Role; Science; Scientist; Site; Source; Stereotyping; Syndrome; Syphilis; Touch sensation; Training; Training Programs; Training and Education; Travel; United States; Universities; Work; antiretroviral therapy; career; clinical care; college; comorbidity; demographics; design; early-career faculty; education research; ethnic minority; experience; faculty mentor; graduate student; high school; human capital; ideation; innovation; interest; multidisciplinary; nervous system disorder; neuroAIDS; next generation; opioid epidemic; programs; racial and ethnic; real world application; recruit; rural area; skills; social stigma; student-centered approach; summer internship; tool; unconscious bias; undergraduate student; urban area

Even though the HIV/AIDS epidemic has been raging for over 30 years, the need for awareness, education, and research remains critically important. Many of our high school trainees, who are now college undergraduates, remain curious about HIV pathogenesis of the central nervous system and why a cure has been so difficult to develop. A few of these trainees have been touched directly, as they hail from countries in which the incidence and prevalence of HIV infection remains high and have observed firsthand its impact on individuals and families in these communities. Such experiences help inspire the development of a research scientist. However, in many regions of the USA, opportunities to do research as an undergraduate are not available locally. This is a critical gap as we know the transformative role that experiential research education experiences play in connecting didactic learning with real-world application and innovative ideation. We hypothesize that by exposing highly motivated undergraduates, particularly those that reside in high HIV-1 incidence/prevalence regions to an education-research mentoring institute focused on NeuroHIV and its associated comorbidities, there will be a significant increase in those who express strong motivation and persistence to pursue a research career in this field. This aim will be accomplished with a suite of tools, resources and human capital leveraged and integrated through our existing successful training programs which include: a didactic web-based course covering basic and clinical research on the complications of HIV infection of the central nervous system, subject area experts from the fields of NeuroHIV, aging, neuroscience, psychiatry and mental health, who will serve as research and career mentors, and as an initial source for recruitment, current undergraduates who participated as high school students in our NIMH-funded training program Project Pipeline Baltimore and showed a strong interest in HIV brain science research. Additional opportunities for education and/or clinical experiences will also be available through our School of Public Health, the Center for AIDS Research, the Bartlett Clinic and the AIDS/HIV Education Center. Through an innovative student-centered approach, the individual development plan approach will be used in one-on-one mentoring with expert faculty mentors to assist trainees in developing and planning their next career steps. Undergraduates will be introduced to cutting-edge topical areas of research necessary for them to develop the skills and knowledge that will enable them to work in a cross-disciplinary fashion. Through the completion of capstone projects and presentations, trainees will develop their abilities to read and understand the scientific literature, and gain practice in the communication of science in written and oral formats. Additional professional development will cover topics such as unconscious bias, stereotype threat, and imposter syndrome. The design of the proposed intervention will help position participants with the knowledge, skills, exposure and training needed for them to tackle and solve important research questions in NeuroHIV and its co-morbid conditions as future graduate students.

尽管艾滋病毒/艾滋病的流行已经肆虐了30多年，但提高认识的必要性， 教育和研究仍然至关重要。我们的许多高中实习生，现在都上大学了 本科生，仍然好奇艾滋病毒的中枢神经系统的发病机制，以及为什么已经治愈 开发起来太难了。这些受训人员中的一些人直接受到了接触，因为他们来自以下国家 艾滋病毒感染的发病率和流行率仍然很高，并已第一手观察到其对个人的影响。 以及这些社区中的家庭。这样的经历有助于激励研究科学家的发展。 然而，在美国的许多地区，作为本科生进行研究的机会在当地是不存在的。 这是一个关键的差距，因为我们知道体验式研究教育经验所起的变革作用。 将授课学习与实际应用和创新思维相结合。我们假设，通过 接触积极进取的本科生，特别是那些居住在艾滋病毒-1高发区的学生 将发病/流行地区转移到一个专注于神经性艾滋病毒及其 相关的合并症，表现出强烈动机的人将显著增加 并坚持不懈地在这一领域从事研究事业。这一目标将通过一套工具来实现， 通过我们现有的成功培训计划利用和整合资源和人力资本 内容包括：以网络为基础的教学课程，涵盖艾滋病毒感染并发症的基础和临床研究 来自神经艾滋病毒、衰老、神经科学、精神病学等领域的学科领域专家 和心理健康，他们将担任研究和职业指导，并作为招聘的初始来源， 作为高中生参加我们NIMH资助的培训项目的应届本科生 巴尔的摩管道公司对艾滋病毒脑科学研究表现出了浓厚的兴趣。更多机会 教育和/或临床经验也将通过我们的公共卫生学院，中心 艾滋病研究、巴特利特诊所和艾滋病/艾滋病毒教育中心。通过以学生为中心的创新 方法，个人发展计划方法将用于与专家教师的一对一指导 辅导员帮助学员发展和规划他们下一步的职业发展。本科生将被介绍给 到尖端专题研究领域，这是他们发展技能和知识所必需的， 他们以跨学科的方式工作。通过完成顶石项目和演示， 学员将培养他们阅读和理解科学文献的能力，并在 以书面和口头形式进行科学交流。其他专业发展将涵盖以下主题 无意识的偏见、刻板印象的威胁和冒名顶替者综合症。拟议干预措施的设计将 帮助学员掌握解决问题所需的知识、技能、曝光度和培训 未来研究生对神经艾滋病毒及其共病的重要研究问题。