The Johns Hopkins NeuroHIV Comorbidities Scholar Program

约翰·霍普金斯大学 NeuroHIV 合并症学者计划

• 批准号: 10586039
• 负责人: AMANDA MARIA BROWN
• 金额: $ 41.66万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-05-10 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10586039
• 关键词: Acquired Immunodeficiency Syndrome; Address; Affect; Age; Aging; Area; Awareness; Baltimore; Basic Science; Bioinformatics; Brain; Cardiovascular Diseases; Central Nervous System; Central Nervous System Infections; Clinic; Clinical; Clinical Research; Communication; Communities; Country; Curiosities; Development; Development Plans; Doctor of Philosophy; Education; Educational Status; Epidemic; Family; First Generation College Students; Frequencies; Funding; Future; Gonorrhea; HIV; HIV Infections; HIV-1; HIV/AIDS; Healthcare; High School Student; Incidence; Individual; Infection; Intervention; Kidney Diseases; Knowledge; Learning; Literature; Liver diseases; Malignant Neoplasms; Mental Health; Mentors; Metabolic dysfunction; Motivation; National Institute of Mental Health; Neurologic Dysfunctions; Neurosciences; Online Systems; Oral; Osteoporosis; Participant; Pathogenesis; Persons; Play; Population; Positioning Attribute; Prevalence; Psychiatry; Public Health Schools; Qualifying; Research; Research Personnel; Resources; Role; Scholars Program; Science; Scientist; Site; Source; Stereotyping; Syndrome; Syphilis; Touch sensation; Training; Training Programs; Travel; United States; Universities; Work; Writing; antiretroviral therapy; career; clinical care; college; comorbidity; demographics; design; early-career faculty; education research; ethnic minority; experience; faculty mentor; graduate student; high school; human capital; ideation; innovation; interest; multidisciplinary; nervous system disorder; neuroAIDS; next generation; opioid epidemic; programs; racial minority; real world application; recruit; rural area; skills; social stigma; student-centered approach; summer internship; tool; unconscious bias; undergraduate student; urban area

Even though the HIV/AIDS epidemic has been raging for over 30 years, the need for awareness, education, and research remains critically important. Many of our high school trainees, who are now college undergraduates, remain curious about HIV pathogenesis of the central nervous system and why a cure has been so difficult to develop. A few of these trainees have been touched directly, as they hail from countries in which the incidence and prevalence of HIV infection remains high and have observed firsthand its impact on individuals and families in these communities. Such experiences help inspire the development of a research scientist. However, in many regions of the USA, opportunities to do research as an undergraduate are not available locally. This is a critical gap as we know the transformative role that experiential research education experiences play in connecting didactic learning with real-world application and innovative ideation. We hypothesize that by exposing highly motivated undergraduates, particularly those that reside in high HIV-1 incidence/prevalence regions to an education-research mentoring institute focused on NeuroHIV and its associated comorbidities, there will be a significant increase in those who express strong motivation and persistence to pursue a research career in this field. This aim will be accomplished with a suite of tools, resources and human capital leveraged and integrated through our existing successful training programs which include: a didactic web-based course covering basic and clinical research on the complications of HIV infection of the central nervous system, subject area experts from the fields of NeuroHIV, aging, neuroscience, psychiatry and mental health, who will serve as research and career mentors, and as an initial source for recruitment, current undergraduates who participated as high school students in our NIMH-funded training program Project Pipeline Baltimore and showed a strong interest in HIV brain science research. Additional opportunities for education and/or clinical experiences will also be available through our School of Public Health, the Center for AIDS Research, the Bartlett Clinic and the AIDS/HIV Education Center. Through an innovative student-centered approach, the individual development plan approach will be used in one-on-one mentoring with expert faculty mentors to assist trainees in developing and planning their next career steps. Undergraduates will be introduced to cutting-edge topical areas of research necessary for them to develop the skills and knowledge that will enable them to work in a cross-disciplinary fashion. Through the completion of capstone projects and presentations, trainees will develop their abilities to read and understand the scientific literature, and gain practice in the communication of science in written and oral formats. Additional professional development will cover topics such as unconscious bias, stereotype threat, and imposter syndrome. The design of the proposed intervention will help position participants with the knowledge, skills, exposure and training needed for them to tackle and solve important research questions in NeuroHIV and its co-morbid conditions as future graduate students.

即使艾滋病毒/艾滋病流行已经肆虐已有30多年了，但需要意识， 教育和研究至关重要。我们许多高中学员，他们现在正在大学 本科生对中枢神经系统的艾滋病毒发病机理保持好奇，以及为什么治愈 如此难以发展。这些受训者中有一些是直接触及的，因为他们来自 艾滋病毒感染的发病率和患病率仍然很高，并直接观察到它对个体的影响 和这些社区的家庭。这种经验有助于激发研究科学家的发展。 但是，在美国的许多地区，作为本科研究的机会在当地不可用。 这是一个关键的差距，因为我们知道经验研究教育经历的变革性角色 在将教学学习与现实世界应用和创新构想联系起来。我们通过 揭露高度动机的本科生，尤其是居住在高HIV-1中的本科生 教育研究指导学院的发病率/患病率专注于神经hiv及其 相关的合并症，那些表达强大动力的人将大幅度提高 并坚持从事这一领域的研究职业。这个目标将通过一套工具来实现， 资源和人力资本通过我们现有的成功培训计划利用和整合，这些计划 包括：基于教学的网络课程，涵盖了有关HIV感染并发症的基本和临床研究 中枢神经系统，神经hiv，衰老，神经科学，精神病学领域的主题专家 和心理健康，将担任研究和职业导师，并作为招聘的最初来源， 当前作为高中生参加NIMH资助的培训计划项目的本科生 巴尔的摩管道对HIV脑科学研究表现出强烈的兴趣。其他机会 教育和/或临床经验也将通过我们的公共卫生学院获得 艾滋病研究，巴特利特诊所和艾滋病/艾滋病毒教育中心。通过以创新的学生为中心 方法，个人发展计划方法将用于与专家教师的一对一指导 指导者协助学员制定和计划其下一步的职业步骤。将介绍本科生 为他们开发技能和知识所必需的尖端局部研究领域 他们以跨学科的方式工作。通过完成顶峰项目和演示文稿， 学员将发展自己的能力来阅读和理解科学文献，并在 以书面和口头格式进行科学的交流。额外的专业发展将涵盖此类主题 作为无意识的偏见，刻板印象威胁和冒名顶替综合症。拟议干预的设计将 帮助参与者对他们解决和解决所需的知识，技能，曝光和培训 Neurohiv及其作为未来研究生的合并状况的重要研究问题。