The Johns Hopkins NeuroHIV Comorbidities Scholar Program

约翰·霍普金斯大学 NeuroHIV 合并症学者计划

• 批准号: 10586039
• 负责人: AMANDA MARIA BROWN
• 金额: $ 41.66万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-05-10 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10586039
• 关键词: Acquired Immunodeficiency Syndrome; Address; Affect; Age; Aging; Area; Awareness; Baltimore; Basic Science; Bioinformatics; Brain; Cardiovascular Diseases; Central Nervous System; Central Nervous System Infections; Clinic; Clinical; Clinical Research; Communication; Communities; Country; Curiosities; Development; Development Plans; Doctor of Philosophy; Education; Educational Status; Epidemic; Family; First Generation College Students; Frequencies; Funding; Future; Gonorrhea; HIV; HIV Infections; HIV-1; HIV/AIDS; Healthcare; High School Student; Incidence; Individual; Infection; Intervention; Kidney Diseases; Knowledge; Learning; Literature; Liver diseases; Malignant Neoplasms; Mental Health; Mentors; Metabolic dysfunction; Motivation; National Institute of Mental Health; Neurologic Dysfunctions; Neurosciences; Online Systems; Oral; Osteoporosis; Participant; Pathogenesis; Persons; Play; Population; Positioning Attribute; Prevalence; Psychiatry; Public Health Schools; Qualifying; Research; Research Personnel; Resources; Role; Scholars Program; Science; Scientist; Site; Source; Stereotyping; Syndrome; Syphilis; Touch sensation; Training; Training Programs; Travel; United States; Universities; Work; Writing; antiretroviral therapy; career; clinical care; college; comorbidity; demographics; design; early-career faculty; education research; ethnic minority; experience; faculty mentor; graduate student; high school; human capital; ideation; innovation; interest; multidisciplinary; nervous system disorder; neuroAIDS; next generation; opioid epidemic; programs; racial minority; real world application; recruit; rural area; skills; social stigma; student-centered approach; summer internship; tool; unconscious bias; undergraduate student; urban area

Even though the HIV/AIDS epidemic has been raging for over 30 years, the need for awareness, education, and research remains critically important. Many of our high school trainees, who are now college undergraduates, remain curious about HIV pathogenesis of the central nervous system and why a cure has been so difficult to develop. A few of these trainees have been touched directly, as they hail from countries in which the incidence and prevalence of HIV infection remains high and have observed firsthand its impact on individuals and families in these communities. Such experiences help inspire the development of a research scientist. However, in many regions of the USA, opportunities to do research as an undergraduate are not available locally. This is a critical gap as we know the transformative role that experiential research education experiences play in connecting didactic learning with real-world application and innovative ideation. We hypothesize that by exposing highly motivated undergraduates, particularly those that reside in high HIV-1 incidence/prevalence regions to an education-research mentoring institute focused on NeuroHIV and its associated comorbidities, there will be a significant increase in those who express strong motivation and persistence to pursue a research career in this field. This aim will be accomplished with a suite of tools, resources and human capital leveraged and integrated through our existing successful training programs which include: a didactic web-based course covering basic and clinical research on the complications of HIV infection of the central nervous system, subject area experts from the fields of NeuroHIV, aging, neuroscience, psychiatry and mental health, who will serve as research and career mentors, and as an initial source for recruitment, current undergraduates who participated as high school students in our NIMH-funded training program Project Pipeline Baltimore and showed a strong interest in HIV brain science research. Additional opportunities for education and/or clinical experiences will also be available through our School of Public Health, the Center for AIDS Research, the Bartlett Clinic and the AIDS/HIV Education Center. Through an innovative student-centered approach, the individual development plan approach will be used in one-on-one mentoring with expert faculty mentors to assist trainees in developing and planning their next career steps. Undergraduates will be introduced to cutting-edge topical areas of research necessary for them to develop the skills and knowledge that will enable them to work in a cross-disciplinary fashion. Through the completion of capstone projects and presentations, trainees will develop their abilities to read and understand the scientific literature, and gain practice in the communication of science in written and oral formats. Additional professional development will cover topics such as unconscious bias, stereotype threat, and imposter syndrome. The design of the proposed intervention will help position participants with the knowledge, skills, exposure and training needed for them to tackle and solve important research questions in NeuroHIV and its co-morbid conditions as future graduate students.

尽管艾滋病毒/艾滋病流行病已经肆虐了30多年，但需要提高认识， 教育和研究仍然至关重要。我们的许多高中实习生，谁现在是大学 大学生，仍然好奇艾滋病毒的中枢神经系统的发病机制，为什么治愈一直是 很难发展。这些受训人员中有一些人受到了直接影响，因为他们来自一些国家， 艾滋病毒感染的发生率和流行率仍然很高，并直接观察到其对个人的影响 这些社区的家庭。这些经历有助于激发研究科学家的发展。 然而，在美国的许多地区，作为本科生进行研究的机会在当地并不存在。 这是一个关键的差距，因为我们知道体验式研究教育体验所发挥的变革作用 将教学式学习与现实世界的应用和创新思维联系起来。我们假设 暴露积极性高的大学生，特别是那些居住在高HIV-1 发病率/流行地区的教育研究指导机构，重点是神经艾滋病毒及其 相关合并症，表达强烈动机的患者将显著增加 并坚持不懈地追求在这一领域的研究事业。这一目标将通过一套工具来实现， 通过我们现有的成功培训计划， 包括：一个基于网络的教学课程，涵盖艾滋病毒感染并发症的基础和临床研究 来自神经艾滋病、衰老、神经科学、精神病学等领域的学科领域专家 和心理健康，谁将担任研究和职业导师，并作为最初的招聘来源， 目前的本科生谁参加了我们的NIMH资助的培训计划项目的高中生 管道巴尔的摩，并表现出对艾滋病毒脑科学研究的浓厚兴趣。其他机会 教育和/或临床经验也将通过我们的公共卫生学院，中心， 艾滋病研究，巴特利特诊所和艾滋病/艾滋病毒教育中心。通过以学生为中心的创新 方法，个人发展计划方法将用于与专家教师一对一的指导 导师协助学员发展和规划他们的下一个职业步骤。本科生将被引入 到尖端的研究必要的专题领域，他们发展的技能和知识，使 让他们以跨学科的方式工作。通过完成顶点项目和演示， 学员将培养他们阅读和理解科学文献的能力，并在 以书面和口头形式进行科学交流。其他专业发展将涵盖以下主题 无意识偏见、刻板印象威胁和冒名顶替综合症。拟议干预措施的设计将 帮助学员掌握应对和解决问题所需的知识、技能、接触和培训 重要的研究问题，在神经艾滋病毒及其共病条件作为未来的研究生。