MICROFABRICATED DEVICES: A SIGNIFICANT ADVANCE FOR THE DETECTION AND MOLECULAR ANALYSES OF CIRCULATING CANCER CELLS?

微型设备：循环癌细胞检测和分子分析的重大进展？

• 批准号: nhmrc : 631939
• 负责人: Dr Catherine O'Doherty
• 金额: $ 28.15万
• 依托单位: University of South Australia
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/microfabricated-devices-significant-cancer-cells/77934
• 关键词: MICROFABRICATED; DEVICES; SIGNIFICANT; ADVANCE; DETECTION

Using advanced microfabrication concepts, this project aims to develop a platform technology able to capture tumour cells circulating in the blood of cancer patients. Although present only in extremely small numbers, these cells provide invaluable insights into the pathophysiology of the disease and consequently provide vital diagnostic and prognostic information. Molecular analyses of these cancer cells could ultimately enable the design of improved and personalized cancer treatment.

利用先进的微制造概念，该项目旨在开发一种能够捕获癌症患者血液中循环的肿瘤细胞的平台技术。虽然只有极少数细胞存在，但这些细胞对疾病的病理生理学提供了宝贵的见解，因此提供了重要的诊断和预后信息。对这些癌细胞的分子分析最终可能使改进和个性化癌症治疗的设计成为可能。