Biostatistics Shared Resources Core

生物统计学共享资源核心

基本信息

  • 批准号:
    10378565
  • 负责人:
  • 金额:
    $ 86.36万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    1997
  • 资助国家:
    美国
  • 起止时间:
    1997-04-01 至 2024-02-29
  • 项目状态:
    已结题

项目摘要

PROJECT SUMMARY/ABSTRACT— Biostatistics Shared Resource The Biostatistics Shared Resource (BSR) is a SJCCC managed shared resource with the overarching mission of impacting pediatric cancer through biostatistics collaboration and consulting, and through comprehensive, effective, and timely biostatistical support to Center members. BSR has a highly experienced and interactive team of biostatisticians who work collaboratively with researchers who are conducting leading edge basic science, clinical research, and population and survivorship research from the 5 SJCCC Programs. This is evidenced by the high level of collaborative publications and key scientific contributions in high-impact journals such as Journal of Clinical Oncology (n=31), Cancer (n=31), Nature Genetics (n=9), and Lancet Oncology (n=4). In addition, BSR biostatisticians are well integrated into the clinical trial teams providing statistical support throughout the life cycle of the research project from concept development through publication. During the last funding period, 85% of all SJCCC publications used the BSR and 77% (n=358/468) of all collaborative publications with a biostatistician as a co-author were associated with SJCCC programs. These included papers from all 5 of the programs: CCSP (n = 103), CBP (n = 1), DBSTP (n = 66), NBTP (n = 83), and HMP (n = 105). A total of 125 St. Jude investigators and their staff used the BSR during the index year (FY2017). Of those, 71 (57%) were SJCCC members. The BSR faculty also offer workshops, office consultations, lectures, seminars, Grand Rounds, and courses on study design, analysis methods, and software implementation to fellows, research staff, and faculty. The BSR is led by Dr. Deo Kumar Srivastava who has more than 23 years' experience in the statistical design and analysis of cancer research and cancer clinical trials. He is supported by 9 faculty biostatisticians and 13 master's-level trained staff, ensuring that BSR support is available to investigators throughout all 5 programs. During our most recent funding period, BSR has witnessed growth driven by the strengthening of the scientific programs, research in genomic characterization of pediatric cancers, and focus on complex precision medicine SJCCC investigator-initiated multisite trials. Goals for the next funding period include continuing to provide state-of-the-art statistical support to all SJCCC investigators including new investigators, and targeted recruitment of biostatisticians to strengthen expertise in personalized medicine, immunotherapy, and in expansion of high-throughput big data. Lastly, BSR will closely partner with the Information Services department in the implementation of the new software provided by the Clinical Trials Management System.
项目总结/摘要-生物统计学共享资源 生物统计学共享资源(BSR)是一种由SJCCC管理的共享资源,其首要使命是 通过生物统计学合作和咨询,以及通过全面的, 为中心成员提供有效和及时的生物统计支持。BSR拥有一个经验丰富的互动 一个生物统计学家团队,他们与从事前沿基础研究的研究人员合作, 科学,临床研究,以及人口和生存率研究,来自5个SJCCC项目。这是 高水平的合作出版物和高影响力期刊上的关键科学贡献证明了这一点 如Journal of Clinical Oncology(n=31)、Cancer(n=31)、Nature Genetics(n=9)和Lancet Oncology(n=4)。 此外,BSR生物统计学家很好地融入了临床试验团队,提供统计支持 在研究项目的整个生命周期中,从概念开发到出版。在过去 在资助期间,85%的SJCCC出版物使用了BSR,77%(n=358/468)的所有合作出版物使用了BSR。 生物统计学家作为合著者的出版物与SJCCC项目相关。其中包括文件 来自所有5个程序:CCSP(n = 103)、CBP(n = 1)、DBSTP(n = 66)、NBTP(n = 83)和HMP(n = 105)。 在索引年(2017财年),共有125名St. Jude研究者及其工作人员使用了BSR。其中,71 (57%)是SJCCC成员。BSR教师还提供研讨会,办公室咨询,讲座,研讨会, 大圆桌会议,并为研究员提供研究设计、分析方法和软件实施课程, 研究人员和教职员工。BSR由Deo Kumar Srivastava博士领导,他拥有超过23年的经验 具有癌症研究和癌症临床试验的统计设计和分析经验。他得到了 9名生物统计学家和13名经过硕士培训的工作人员,确保生物统计学研究支持可用于 在所有5个项目中进行调查。在我们最近的融资期间,BSR见证了增长 在加强科学方案的推动下,对儿科癌症的基因组特征进行研究, 并专注于复杂的精准医学SJCCC治疗仪启动的多中心试验。下一次融资的目标 期间包括继续为所有SJCCC研究者提供最先进的统计支持,包括新的 研究人员,并有针对性地招聘生物统计学家,以加强个性化医疗的专业知识, 免疫疗法,以及高通量大数据的扩展。最后,BSR将与 政府新闻处在推行由临床试验所提供的新软件时, 管理系统.

项目成果

期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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MOTOMI MORI其他文献

MOTOMI MORI的其他文献

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{{ truncateString('MOTOMI MORI', 18)}}的其他基金

Biostatistics Shared Resources Core
生物统计学共享资源核心
  • 批准号:
    10116300
  • 财政年份:
    2020
  • 资助金额:
    $ 86.36万
  • 项目类别:
Biostatistics Shared Resources Core
生物统计学共享资源核心
  • 批准号:
    9883738
  • 财政年份:
    2020
  • 资助金额:
    $ 86.36万
  • 项目类别:
BIOSTATISTICS SHARED RESOURCE
生物统计共享资源
  • 批准号:
    8340108
  • 财政年份:
    2011
  • 资助金额:
    $ 86.36万
  • 项目类别:
CORE--Biostatistics
核心--生物统计学
  • 批准号:
    7109839
  • 财政年份:
    2005
  • 资助金额:
    $ 86.36万
  • 项目类别:
CORE--BIOSTATISTICS AND BIOINFORMATICS
核心——生物统计学和生物信息学
  • 批准号:
    6783960
  • 财政年份:
    2004
  • 资助金额:
    $ 86.36万
  • 项目类别:
Biostatistics Shared Resource
生物统计共享资源
  • 批准号:
    10205358
  • 财政年份:
    1997
  • 资助金额:
    $ 86.36万
  • 项目类别:
Biostatistics Shared Resources Core
生物统计学共享资源核心
  • 批准号:
    10582652
  • 财政年份:
    1997
  • 资助金额:
    $ 86.36万
  • 项目类别:
IMPLICATIONS OF HLA POLYMORPHISM FOR DONOR RECRUITMENT
HLA 多态性对捐赠者招募的影响
  • 批准号:
    2234923
  • 财政年份:
    1996
  • 资助金额:
    $ 86.36万
  • 项目类别:
IMPLICATIONS OF HLA POLYMORPHISM FOR DONOR RECRUITMENT
HLA 多态性对捐赠者招募的影响
  • 批准号:
    2901242
  • 财政年份:
    1996
  • 资助金额:
    $ 86.36万
  • 项目类别:
IMPLICATIONS OF HLA POLYMORPHISM FOR DONOR RECRUITMENT
HLA 多态性对捐赠者招募的影响
  • 批准号:
    2685483
  • 财政年份:
    1996
  • 资助金额:
    $ 86.36万
  • 项目类别:

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