BIOSTATISTICS SHARED RESOURCE

生物统计共享资源

• 批准号: 8340108
• 负责人: MOTOMI MORI
• 金额: $ 10.11万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-20 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8340108
• 关键词: Address; Adopted; Applications Grants; Award; Back; Basic Science; Biometry; Biostatistics Shared Resource; Budgets; Cancer Biology; Cancer Center; Cancer Center Support Grant; Cancer Research Project; Categories; Charge; Clinical Protocols; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Concept Formation; Consult; Consultations; Data; Data Analyses; Development; Education; Educational workshop; Environment; Epidemiology; Etiology; Experimental Designs; Funding; Genetic; Genomics; Goals; Grant; Health; Hour; Individual; Institutes; Institution; Instruction; Journals; K-Series Research Career Programs; Knowledge; Laboratories; Malignant Neoplasms; Manuscripts; Medical center; Mentors; Monitor; Pilot Projects; Play; Population Sciences; Preparation; Prevention; Proteomics Shared Resource; Protocols documentation; Public Health; Publications; Publishing; Research; Research Design; Research Infrastructure; Research Personnel; Research Support; Resource Sharing; Review Committee; Role; Safety; Sample Size; Staging; System; Training; Training Activity; Training and Education; Triage; United States National Institutes of Health; anticancer research; cost effective; data management; meetings; member; new technology; operation; programs

The Biostatistics Shared Resource (BSR) of the Knight Cancer Institute (Knight) is a cancer-center managed shared resource and provides biostatistics support to basic, clinical and population science researchers who conduct cancer research at OHSU and partner institutions (e.g., Portland VA Medical Center, Kaiser Permanente Center for Health Research). In addition to providing support to individual researchers, the BSR also assists other Knight shared resources in addressing their biostatistics needs. The BSR strives to enhance the scientific quality and statistical sophistication of cancer research through tailored professional consultation at every level and stage of cancer research. By leveraging CCSG support, the Knight institutional commitment, and other cancer specific grant support, the BSR provides a wide range of biostatistics expertise and supports cancer researchers in a cost-effective manner. Support activities are divided into four major categories: (1) pre-award support, (2) post-award support, (3) infrastructure support, and (4) education and training. Pre-award support includes consultation on study and experimental designs, sample size and power analysis, and statistical analysis plan for investigator-initiated clinical protocols and grant proposals. Post-award support includes protocol implementation, data management, statistical analysis, and manuscript preparation. Infrastructure support refers to collaborative projects with other shared resources to enhance the overall research infrastructure, including development and implementation of statistical protocols for high-throughput genetics/genomics studies, clinical research support through participation in the Protocol Review and Monitorihg^System (i.e., Clinical Research Review Committee and Data and Safety Monitoring Committee). Education and training activities include participation in various cancer journal clubs, research-in-progress meetings, short-term biostatistics workshops, didactic courses in clinical trials and statistical genetics, and professional development activities for BSR members. The BSR is highly utilized and has contributed significantly to cancer research conducted at the Knight. In 2009 the BSR assisted a total of 129 projects from 55 investigators from all four research programs, provided a total of 2,562 consulting hours for investigator-support activities. Between 2005 and 2010, the BSR assisted 65 cancer relevant publications (65 published, 9 in press, revision or submitted). The BSR emphasizes research collaboration at the earliest stage possible as most productive research is conducted under a collaborative research environment

奈特癌症研究所 (Knight) 的生物统计共享资源 (BSR) 是一个癌症中心管理的 共享资源，并为在 OHSU 和合作机构（例如波特兰 VA 医疗中心、凯撒医疗机构健康研究中心）进行癌症研究的基础、临床和人口科学研究人员提供生物统计支持。除了为个别研究人员提供支持外，BSR 还协助其他 Knight 共享资源来满足他们的生物统计需求。 BSR 致力于 通过在癌症研究的各个层面和阶段提供量身定制的专业咨询，提高癌症研究的科学质量和统计复杂性。通过利用 CCSG 支持、Knight 机构承诺和其他癌症特定拨款支持，BSR 提供​​广泛的生物统计学专业知识，并以具有成本效益的方式支持癌症研究人员。支持活动分为四大类：（1）授标前支持，（2）授标后支持，（3）基础设施支持，以及（4）教育和培训。授予前支持包括研究和实验设计、样本量和功效分析以及研究者发起的临床方案和资助提案的统计分析计划的咨询。获奖后支持包括方案实施、数据管理、统计分析和稿件准备。基础设施支持是指与其他共享资源的合作项目，以增强整体研究基础设施，包括高通量遗传学/基因组学研究统计方案的开发和实施，通过参与方案审查和监测系统（即临床研究审查委员会和数据和安全监测委员会）提供临床研究支持。教育和培训活动包括参加各种 癌症期刊俱乐部、正在进行的研究会议、短期生物统计学研讨会、临床试验和统计遗传学教学课程以及 BSR 成员的专业发展活动。 BSR 得到高度利用，并为 Knight 进行的癌症研究做出了重大贡献。 2009 年，BSR 总共协助了来自所有四个研究计划的 55 名研究人员的 129 个项目，总共提供了 2,562 小时的调查员支持活动咨询时间。 2005年至2010年间，BSR协助了65篇癌症相关出版物（65篇已发表，9篇正在出版、修订或提交）。 BSR 强调尽早进行研究合作，因为大多数富有成果的研究都是在合作研究环境下进行的