Genetic Counseling (GC)

遗传咨询共享资源 摘要 遗传咨询共享资源（GC）促进基础科学，临床和行为研究 将遗传学发现转化为临床护理的必要性。GC提供临床遗传学服务， 自2003年以来，我一直支持亨斯迈癌症研究所（HCI）的遗传研究（由癌症中心支持 自2009年以来一直由Wendy Kohlmann，MS，CGC指导。GC是 HCI的使命的精髓，并建立在HCI的基因发现的悠久历史，通过领先的实践改变 研究致力于确定基因检测的临床效用，风险沟通的最佳方法 提供遗传咨询，以及管理遗传性癌症风险的策略 倾向GC是癌症中心的主要目标之一，将科学发现带到临床 and into applications应用for the population人口. GC提供翻译遗传学所必需的几个关键服务， 研究，包括为基因研究或综合征研究确定患者队列;帮助 研究人员设计研究，以最佳地纳入遗传信息， 与遗传分析有关的法律的和社会问题;提供遗传咨询干预;收集 临床表型和纵向结果数据。GC的目标是1）提供癌症遗传学 专业知识，遗传咨询服务和干预措施，以及2）支持科学研究目标， 癌症中心，特别是在遗传学翻译到临床和人口的背景下。 获得研究遗传咨询服务使癌症中心成员能够研究新的 提供遗传信息的方法，并包括我们整个流域的参与者，国家 来自犹他州。GC通过确保所有癌症中心都能获得遗传学专业知识，为癌症中心增加价值。 成员和临床研究者。GC在HCI中的广泛影响由其对61 自2014年以来出版。拥有同行评审资金的癌症中心成员占用户的53%， GC的工作100%与癌症有关。 HCI建立高质量、以研究为导向的遗传咨询共享资源，具有高度的 创新和独特的国家癌症研究所癌症中心。联合国共同基金会主任和工作人员 资源参与国家委员会，他们通过整合 研究结果转化为遗传性癌症的基因检测和管理指南。GC允许HCI在所有方面都出类拔萃 遗传性癌症研究领域，并成为遗传发现和将发现转化为 临床实施和人口政策。

GENETIC COUNSELING SHARED RESOURCE ABSTRACT The Genetic Counseling Shared Resource (GC) facilitates basic science, clinical, and behavioral research necessary to translate genetic discoveries into clinical care. GC has provided clinical genetics services and supported genetic research at Huntsman Cancer Institute (HCI) since 2003 (supported by the Cancer Center Support Grant since 2009) and has been directed by Wendy Kohlmann, MS, CGC, since 2006. GC is quintessential to HCI’s mission and builds on HCI’s long history of gene discovery by leading practice-changing research endeavors to determine the clinical utility of genetic testing, optimal methods for risk communication and delivery of genetic counseling, and strategies to manage risk conveyed by inherited cancer predispositions. GC is integral to a major goal of the Cancer Center, bringing scientific discoveries to the clinic and into applications for the population. GC provides several key services necessary for translational genetic research, including identifying cohorts of patients for gene research or studies of syndromes; helping investigators design studies to optimally incorporate genetic information and to anticipate and address ethical, legal, and social issues related to genetic analysis; providing genetic counseling interventions; and collecting clinical phenotypes and longitudinal outcomes data. The aims of GC are 1) to provide cancer genetics expertise, genetic counseling services, and interventions, and 2) to support the scientific research objectives of the Cancer Center, especially in the context of translation of genetics to the clinic and population. Access to research genetic counseling services has allowed Cancer Center members to study novel approaches for providing genetic information and to include participants across our catchment area, the State of Utah. GC adds value to the Cancer Center by ensuring genetics expertise is available to all Cancer Center members and clinical investigators. The broad impact of GC across HCI is indicated by its contribution to 61 publications since 2014. Cancer Center members with peer-reviewed funding comprise 53% of the users, and 100% of GC’s work is cancer-related. HCI’s establishment of a top-quality, research-oriented Genetic Counseling Shared Resource is highly innovative and unique among National Cancer Institute cancer centers. The Director and staff of the Shared Resource participate in national committees, and they extend the impact of HCI research by incorporating findings into guidelines for genetic testing and management of hereditary cancer. GC allows HCI to excel in all areas of hereditary cancer research and to be a leader in genetic discoveries and translation of findings into clinical implementation and population policy.