Genetic Counseling (GC)

遗传咨询（GC）

• 批准号: 9918298
• 负责人: Wendy K Kohlmann
• 金额: $ 1.11万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9918298
• 关键词: Abbreviations; Address; Advanced Malignant Neoplasm; Advisory Committees; Amendment; BRCA1 gene; BRCA2 gene; Back; Basic Science; Behavioral Research; Behavioral trial; Budgets; CDKN2A gene; Cancer Center; Cancer Center Support Grant; Clinical; Clinical Research; Clinical Trials; Communication; Community Health Education; Community Healthcare; Complex; Consultations; Counseling; Data; Distant; Early Diagnosis; Education; Environment; Ethical Issues; Ethics; Faculty; Family; Funding; Genes; Genetic; Genetic Counseling; Genetic Research; Genetic Services; Genetic screening method; Genetic study; Goals; Health Personnel; Hereditary Malignant Neoplasm; Individual; Infrastructure; Inheritance Patterns; Inherited; Institutes; Intervention; Investigation; Knowledge; Laboratories; Lead; Legal; Location; Malignant Neoplasms; Medical Genetics; Medical Records; Methodology; Mission; Modeling; Morbidity - disease rate; Outcome; Participant; Patient Education; Patient Recruitments; Patients; Peer Review; Penetrance; Persons; Play; Population Database; Population Research; Predisposition; Professional Education; Professional counselor; Protocols documentation; Provider; Psychosocial Influences; Publications; Recording of previous events; Research; Research Design; Research Personnel; Research Support; Resource Sharing; Resources; Risk; Risk Assessment; Role; Sampling; Services; Supervision; Surveys; Syndrome; Training Programs; Translating; Universities; Utah; Work; acronyms; behavioral outcome; behavioral study; cancer genetics; cancer prevention; cancer risk; cancer type; clinical care; clinical practice; cohort; cost; design; ethical legal social implication; experience; flexibility; gene discovery; genetic counselor; implementation research; improved; lectures; member; mortality; neoplasm resource; outreach; personalized cancer therapy; psychosocial; recruit; research study; satisfaction; success; symposium; translational research program

GENETIC COUNSELING SHARED RESOURCE ABSTRACT The Genetic Counseling (GC) Shared Resource provides cutting-edge genetic services and expertise at an affordable cost to University of Utah (U of U) investigators conducting research related to the inherited basis of cancer. The GC Shared Resource has provided clinical genetics services and supported genetic research at Huntsman Cancer Institute (HCI) since 2003. It was first competed for CCSG support in 2009. Wendy Kohlmann, MS, CGC, a senior genetic counselor, has managed the core since 2006; she oversees a team that includes four additional board-certified genetic counselors and support staff. To achieve its goal of advancing cancer genetics research, the GC Shared Resource provides services including: identifying and recruiting appropriate participants and controls for genetic studies, aiding in study design, addressing ethical and psychosocial issues associated with genetic research, collecting and interpreting family histories, stratifying risk, developing and implementing tailored genetic counseling interventions, and interpreting data. The GC team works individually with investigators to inform them about the services, expertise, infrastructure, data, and biospecimens available through the GC Shared Resource for genetic research and to determine the feasibility and appropriate design of potential studies. The Resource supports funded research through the course of the project, from study design to publication stages. Individuals and families with hereditary cancer susceptibilities are rare, and identifying and recruiting participants for genetic research has the potential to be cost prohibitive. The GC Shared Resource adds important value to the Cancer Center by identifying and maintaining cohorts of individuals and families with various cancer risk profiles so samples and data are readily available for investigators. The GC Shared Resource has also expanded research opportunities by providing infrastructure to return genetic findings back to participants. The GC Shared Resource contributes to a robust translational research program in which genetic discoveries lead to subsequent behavioral and clinical studies, thereby contributing to cancer genetic research at the U of U, as well as cancer prevention and personalized cancer treatment at HCI. The GC Shared Resource is a Cancer Center-managed facility with supervision from HCI Directors and a Faculty Advisory Committee. Surveys are used to assess user satisfaction. The Resource is located in HCI and is thus easily accessible to all Cancer Center members and other campus users. In 2013, use of the Resource by Cancer Center members with peer-reviewed funding exceeded 80%, while the CCSG budget request is only 6% ($37,894) of the total proposed budget.

遗传咨询共享资源 摘要 遗传咨询（GC）共享资源提供尖端的遗传服务和专业知识， 犹他州大学（U of U）研究人员进行与遗传基础相关的研究时， 癌GC共享资源提供临床遗传学服务，并支持遗传学研究， 亨斯迈癌症研究所（HCI）自2003年以来。它于2009年首次获得CCSG的支持。温迪 Kohlmann，MS，CGC，高级遗传顾问，自2006年以来一直管理核心;她监督一个团队， 包括四个额外的董事会认证的遗传咨询师和支持人员。 为了实现推进癌症遗传学研究的目标，GC共享资源提供服务 包括：确定和招募适当的参与者和对照进行遗传研究， 设计，解决与遗传研究有关的伦理和心理问题，收集和 解释家族史，风险分层，开发和实施定制的遗传咨询 干预和解释数据。GC团队与调查人员单独合作，告知他们 通过GC共享资源提供的服务、专业知识、基础设施、数据和生物标本， 基因研究，并确定可行性和适当的设计潜在的研究。资源 在整个项目过程中支持资助的研究，从研究设计到出版阶段。 具有遗传性癌症易感性的个人和家庭是罕见的， 遗传研究的参与者可能会因费用过高而望而却步。GC共享资源添加 通过识别和维护患有癌症的个人和家庭的队列，对癌症中心具有重要价值。 各种癌症风险特征，因此研究人员可以随时获得样本和数据。GC分享 资源还通过提供基础设施将遗传发现返回， 给参与者。GC共享资源有助于一个强大的翻译研究计划，其中 遗传学的发现导致了随后的行为和临床研究，从而有助于癌症的遗传学研究。 研究在U的U，以及癌症预防和个性化的癌症治疗在HCI。 GC共享资源是一个癌症中心管理的设施，由HCI董事和 一个教师咨询委员会。调查用于评估用户满意度。资源位于HCI 因此，所有癌症中心成员和其他校园用户都可以轻松访问。2013年，使用 癌症中心成员的资源与同行评审的资金超过80%，而CCSG预算 这一要求仅占拟议预算总额的6%（37，894美元）。